Results 41 to 50 of about 22,114 (260)
On the translation-proper of toponyms in Romanian translations at the beginning of the 19th century [PDF]
Diacronia, 2018 The translation of certain toponyms that had not yet been assimilated to the Romanian language at the beginning of the 19th century represented a real challenge for translators at that time.
Dinu Moscal
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„Idegen szülöttet […] csempész a családi név alá”
Névtani Értesítő, 2021 “Smuggling an illegitimate child […] into the family” Name and names in literary approaches to translation The study formulates hypotheses for a more extensive historical examination of the connections and relations of names and translation ...
ILDIKÓ JÓZAN
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Proper Names: Translating Reference and Application
Journal of the College of Basic Education, 2022 غالبًا ما تُعتبر ترجمة أسماء العلم عملية آلية بسيطة للترجمة من لغة إلى أخرى ، نظرًا لوجهة النظر القائلة بأن الأسماء الصحيحة ليست سوى تسميات تُستخدم لتعريف شخص أو شيء حتى لا تتطلب ترجمتها على أنها ليس لها معنى ولا تحمل حواس.قد يكون هذا الافتراض خاطئًا لأن معظم الأسماء الصحيحة ليست مجرد تحديد للتسميات بل لها نوع من المعاني أو المعاني الخاصة بها والتي ...
openaire +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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Névtani Értesítő, 2015 The aim of this study is to present the problems that may be raised by the translation of proper names on different levels of context, and the methods with which translators can solve these issues.
Vermes, Albert
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
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