Results 61 to 70 of about 359,220 (298)
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Névtani Értesítő, 2015 The aim of this study is to present the problems that may be raised by the translation of proper names on different levels of context, and the methods with which translators can solve these issues.
Vermes, Albert
doaj
, 2006 A history of the notion of PROPERHOOD in philosophy and linguistics is given. Two long-standing ideas, (i) that proper names have no sense, and (ii) that they are expressions whose purpose is to refer to individuals, cannot be made to work ...
Coates, Richard
core +2 more sources
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock +4 more
wiley +1 more source
THE TRANSLATION ANALYSIS OF PROPER NAMES IN FANTASY FILM “THE HOBBIT: AN UNEXPECTED JOURNEY” :A Case Study of English – Indonesian Translation: [PDF]
, 2014 The present research entitled The Translation Analysis of Proper Names in Fantasy Film “The Hobbit: An Unexpected Journey” aims at discovering types of proper names and analyzing the translation procedures dealing with the proper names in the film.
Yulianto, Dimas
core
Observing Users - Designing clarity a case study on the user-centred design of a cross-language information retrieval system [PDF]
, 2004 This paper presents a case study of the development of an interface to a novel and complex form of document retrieval: searching for texts written in foreign languages based on native language queries.
Ballesteros +40 more
core +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Między Oryginałem a Przekładem, 2014 Bella signora dai capelli turchini, or maybe o kruczoczarnych włosach – the translation of proper names in the Polish dubbed version of Roberto Benigni’s Pinocchio The translation of proper names depends to a great extent on cultural marking, on the ...
Werona Król‑Gierat
doaj +1 more source