Results 51 to 60 of about 22,114 (260)

Bella signora dai capelli turchini czy może o kruczoczarnych włosach – przekład nazw własnych w polskiej wersji dubbingowej Pinocchia Roberta Benigniego

open access: yesMiędzy Oryginałem a Przekładem, 2014
Bella signora dai capelli turchini, or maybe o kruczoczarnych włosach – the translation of proper names in the Polish dubbed version of Roberto Benigni’s Pinocchio The translation of proper names depends to a great extent on cultural marking, on the ...
Werona Król‑Gierat
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Fordítsam vagy ne?

open access: yesNévtani Értesítő, 2015
To translate or not to translate? A literary translator’s dilemmas of proper names with respect to speculative fiction     The paper attempts to list the dilemmas proper names present to literary translators based on the author’s own and others ...
Anikó Sohár
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Translation of Onomatopoetic Component in Onomastics

open access: yesRussian journal of linguistics: Vestnik RUDN, 2015
This article covers the topic of the description of translation strategies of onomatopoetic component of proper names. The term of onomatopoetic proper names is introduced for the first time.
Anna V Sokolova
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

A személynevek fordítása Mikszáth Kálmán Szent Péter esernyője című regényének legújabb szlovák kiadásában

open access: yesNévtani Értesítő, 2015
Examining personal names in the latest Slovakian translation of the novel entitled St. Peter’s Umbrella by Kálmán Mikszáth     The paper discusses the translatability and untranslatability of personal names in connection with the latest ...
Flóra Peťovská
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

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