Results 31 to 40 of about 281,980 (313)

Evaluation of the partners in research course: a patient and researcher co-created course to build capacity in patient-oriented research

open access: yesResearch Involvement and Engagement, 2021
Plain English Summary Patient-oriented research (POR) is the meaningful inclusion of patients as active contributing partners in research. In meaningful POR, patients are engaged and valued as contributory members of the research team throughout the ...
Melissa Courvoisier   +5 more
doaj   +1 more source

Large-scale reordering model for statistical machine translation using dual multinomial logistic regression [PDF]

open access: yes, 2014
Phrase reordering is a challenge for statistical machine translation systems. Posing phrase movements as a prediction problem using contextual features modeled by maximum entropy-based classifier is superior to the commonly used lexicalized reordering ...
Niranjan, Mahesan   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Working with Bilingual Corpora to Enhance Legal Translation Competence

open access: yesRomanian Journal of English Studies, 2018
Although there has been harmonisation work on translator training, different programmes still show a different focus. The current paper frames a training project aiming at developing Master’s students specialised translation competence while working with
Oțăt Diana
doaj   +1 more source

Accuracy-based scoring for phrase-based statistical machine translation [PDF]

open access: yes, 2010
Although the scoring features of state-of-the-art Phrase-Based Statistical Machine Translation (PB-SMT) models are weighted so as to optimise an objective function measuring translation quality, the estimation of the features themselves does not have ...
Galron, Daniel   +3 more
core  

Translation as human-computer interaction [PDF]

open access: yes, 2012
This paper seeks to characterise translation as a form of human-computer interaction. The evolution of translator-computer interaction is explored and the challenges and benefits are enunciated.
O'Brien, Sharon, O\u27Brien, Sharon
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPACTS OF GLOBAL PANDEMIC ON TRANSLATOR’S CAREER AND TRANSLATOR TRAINING

open access: yesCurrent Trends in Translation Teaching and Learning E, 2021
The translation market as well as many other businesses and activities have been affected by the lockdown of economies in the whole world since the beginning of 2019. Under the impacts of COVID-19 pandemic, translator’s career has undergone some major and minor transformations.
Kasperė, Ramunė   +1 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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