Results 31 to 40 of about 10,052 (217)
Frontiers in Cellular and Infection Microbiology, 2017 Mycobacterium bovis (M. bovis) is the pathogen of animals and humans that can replicate in the phagosomes of myeloid cells. Cytosolic detection of bacterial products plays a crucial role in initiating the innate immune response, including autophagy ...
Liu Chunfa +6 more
doaj +1 more source
Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]
, 2009 Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card +21 more
core +1 more source
Neuropathological and molecular comparison between clinical and asymptomatic bovine spongiform encephalopathy cases [PDF]
, 2018 Interest in the proper neuropathological and molecular characterization of bovine spongiform encephalopathy (BSE) has increased since asymptomatic and atypical cases were detected in the cattle population by active disease surveillance.
Sisó, Silvia +6 more
core +2 more sources
Methods for differentiating prion types in food-producing animals [PDF]
, 2015 Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by the conformation of the disease form of the prion protein (PrPSc).
Gough, Kevin C. +3 more
core +2 more sources
Advanced survival models for risk-factor analysis in scrapie [PDF]
, 2007 Because of the confounding effects of long incubation duration and flock management, accurate epidemiological studies of scrapie outbreaks are difficult to carry out.
Andréoletti, Olivier +6 more
core +4 more sources
People and Nature, EarlyView.Abstract Pastoral practices remain a widespread economic activity across European mountain regions. However, the viability of this activity may be threatened by the recovery of large wild vertebrates associated with passive rewilding, leading to the so‐called human–wildlife conflicts.
P. Acebes +4 more
wiley +1 more source
The Molecular Pathology of Prion Diseases [PDF]
, 2004 Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen +2 more
core
An overview of animal prion diseases
Virology Journal, 2011 Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion diseases is associated with the accumulation of aggregates of misfolded conformers of host-encoded cellular prion ...
Imran Muhammad, Mahmood Saqib
doaj +1 more source
Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease. [PDF]
PLoS ONE, 2013 Prion diseases are rare but invariably fatal neurodegenerative disorders. They are associated with spongiform encephalopathy, a histopathology characterized by the presence of large, membrane-bound vacuolar structures in the neuropil of the brain.
Derek Silvius +8 more
doaj +1 more source
microRNA-146a as a biomarker for transmissible spongiform encephalopathy
Folia Neuropathologica, 2022 The pro-inflammatory, innate-immune system ribonucleic acid mediator microRNA-146a, constitutively expressed in the brain and central nervous system (CNS) of both the mouse and the human, is pathologically up-regulated in multiple transmissible ...
Aileen Pogue, Yuhai Zhao, Walter Lukiw
doaj +1 more source