Results 1 to 10 of about 1,026 (124)

Noninvasive quantification of granzyme B in cardiac allograft rejection using targeted ultrasound imaging [PDF]

Frontiers in Immunology, 2023
ObjectiveEndomyocardial biopsy is the gold standard method for the diagnosis of cardiac allograft rejection. However, it causes damage to the heart.
Yunjie Jin, Yunjie Jin, Peng Gao, Lifei Liang, Lifei Liang, Yuhang Wang, Jiawei Li, Jiawei Li, Jiyan Wang, Jiyan Wang, Jiangang Hou, Cheng Yang, Cheng Yang, Cheng Yang, Xiaolin Wang   +14 more
doaj   +2 more sources

Two Compartment Evaluation of Liver Grafts During Acellular Room Temperature Machine Perfusion (acRTMP) in a Rat Liver Transplant Model [PDF]

Frontiers in Medicine, 2022
BackgroundSubnormothermic machine perfusion (SNMP) of liver grafts is currently less clinically developed than normothermic and hypothermic approaches, but may have logistical advantages.
Nader Abraham, Min Zhang, Paul Cray, Qimeng Gao, Kannan P. Samy, Ryan Neill, Greta Cywinska, JonCarlo Migaly, Riley Kahan, Arya Pontula, Samantha E. Halpern, Caroline Rush, Jude Penaflor, Samuel J. Kesseli, Madison Krischak, Mingqing Song, Matthew G. Hartwig, Justin J. Pollara, Andrew S. Barbas   +18 more
doaj   +2 more sources

Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse [PDF]

Cells, 2020
Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient ...
Salim Oulghazi, Sarah K. Wegner, Gabriele Spohn, Nina Müller, Sabine Harenkamp, Albrecht Stenzinger, Thalia Papayannopoulou, Halvard Bonig   +7 more
doaj   +2 more sources

Immunosuppressive protocols with tacrolimus after cryopreserved aortal allotransplantation in rats. [PDF]

PLoS ONE, 2018
OBJECTIVES AND DESIGN:The aim of our study was to simulate in rats all aspects and techniques used in our new clinical program of cryopreserved alloarterial transplantation and investigate the influence of two immunosuppressive protocols with tacrolimus ...
Rudolf Spunda, Jan Hruby, Pavel Mericka, Mikulas Mlcek, Ondrej Pecha, Kathrin Splith, Moritz Schmelzle, Felix Krenzien, Jaroslav Lindner, Ivan Matia, Miroslav Spacek   +10 more
doaj   +2 more sources

The role of HIF-1α-VEGF pathway in bronchiolitis obliterans after lung transplantation [PDF]

Journal of Cardiothoracic Surgery, 2019
Background Graft function may be affected if the organ is exposed to hypoxia. We hypothesized that bronchiolitis obliterans (BO) after lung transplantation is associated with hypoxia-inducible factor-1α (HIF-1α). This study compares the expression of HIF-
Haichao Xu, Abudumailamu Abuduwufuer, Wang Lv, Zhenyu Zhou, Yunhai Yang, Chong Zhang, Jian Hu   +6 more
doaj   +2 more sources

DIEP Flap Transplantation in Monozygotic Twins for Breast Reconstruction: A Case Report and Literature Review

Journal of Reconstructive Microsurgery Open, 2023
Background Composite tissue allotransplants are performed for various defects when local, or distant reconstructive options are limited. Though this type of transplant replaces similar tissue, it is complicated by immunosuppression.
Cemile Nurdan Ozturk, Arvind D. Manisundaram, Mariangela Rivera, Can Ozturk, Wong Moon   +4 more
doaj   +1 more source

Role of Hyperglycemia in Isogeneic Islet Transplantation: An Experimental Animal Study [PDF]

Experimental and Clinical Endocrinology & Diabetes, 2008
Study the role of hyperglycemia-induced beta cell loss on grafted islet destruction.Male inbred rats were made diabetic by streptozotocin administration and used as islet donors and/or isograft recipients to probe directly the role of hyperglycemia as an important determinant of transplanted islet fate, following exclusion of immune-related causes of ...
I, Nomikos, K, Kalogerakos, E, Athanasiou, E, Plakokefalos, E, Plakokefales, D, Sioutopoulou, M, Satra, N C, Vamvakopoulos   +7 more
openaire   +2 more sources

Cuff Anastomosis of Both Renal Artery and Vein to Minimize Thrombosis: A Novel Method of Kidney Transplantation in Mice

Journal of Investigative Surgery, 2022
Objectives Anastomosis of renal artery and renal vein in mouse models of kidney transplantation is technically challenging. Conventional technique using suture may result in vascular thrombosis.
Yi Yu, Jun Li, Zirong Bi, Chenglin Wu, Shicong Yang, Qifeng Jiang, Ronghai Deng, Qian Fu, Longshan Liu, Changxi Wang   +9 more
doaj   +1 more source

High-dose atorvastatin reduces oxidative stress of ischemia/reperfusion injury after isogeneic kidney transplantation in rats: in vivo, preclinical, case–control, open-label study

Renal Replacement Therapy, 2023
Background Renal ischemia/reperfusion injury is an unavoidable event in transplantation in which free radical-mediated injury determines release of pro-inflammatory cytokines and activation of innate immunity.
Giacomo Cusumano, Edoardo Cola, Gionata Spagnoletti, Anna Severino, Simona Giubilato, Egidio Stigliano, Maria Emiliana Caristo, Gisella Vischini, Giovanna Liuzzo, Maria Paola Salerno, Filippo Crea, Jacopo Romagnoli   +11 more
doaj   +1 more source

The glomerular filtration rate of isogeneically transplanted rat kidneys

Kidney International, 1982
The glomerular filtration rate (GFR) was determined in rats with an isogeneic kidney transplant and compared with that of unilaterally nephrectomized rats. Experiments were carried out in adult rats, 3 months of age, weighing approximately 300 g, as well as in juvenile rats, 6 to 8 weeks of age, weighing approximately 170 g.
Provoost, Abraham P., de Keijzer, Marinus H., Kort, Wil J., Wolff, Erik D., Molenaar, Jan C.   +4 more
openaire   +2 more sources