Results 11 to 20 of about 1,026 (124)

Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Delayed Wound Healing in Diabetic Rats

Journal of Diabetes Research, 2013
In this paper, we established a delayed wound healing model on diabetic rat to mimic the pathophysiology of clinical patients who suffered from diabetic foot ulcers.
Jiangbo Wan, Liulu Xia, Wenjia Liang, Yi Liu, Qian Cai   +4 more
doaj   +2 more sources

Nanotherapeutics in transplantation: How do we get to clinical implementation? [PDF]

Am J Transplant, 2022
Patients undergoing organ transplantation transition from one life‐altering issue (organ dysfunction) to a lifelong commitment—immunosuppression. Regimens of immunosuppressive agents (ISAs) come with significant side effects and comorbidities. Recently, the use of nanoparticles (NPs) as a solution to the problems associated with the long‐term and ...
Plumblee L, Atkinson C, Jaishankar D, Scott E, Tietjen GT, Nadig SN.   +5 more
europepmc   +2 more sources

Whole‐Genome Sequencing Revealed a Late‐Maturing Isogenic Rice Koshihikari Integrated with Hd16 Gene Derived from an Ise Shrine Mutant

International Journal of Genomics, Volume 2022, Issue 1, 2022., 2022
We identified the key genes controlling the late maturation of the Japonica cultivar Isehikari, which was found at Ise Jingu Shrine and matures 6 days later than Koshihikari. We conducted a genetics‐based approach through this study. First, the latest mature plants, which flowered later than Isehikari, were segregated in the F2 and F3 generations of ...
Motonori Tomita, Ryotaro Tokuyama, Shosuke Matsumoto, Kazuo Ishii, Vijay Gahlaut   +4 more
wiley   +1 more source

A Comprehensive Update of Cerebral Organoids between Applications and Challenges

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
The basic technology of stem cells has been developed and created organoids, which have established a strong interest in regenerative medicine. Different cell types have been used to generate cerebral organoids, which include interneurons and oligodendrocytes (OLs). OLs are fundamental for brain development.
Xiaodong Li, Abdullah Shopit, Jingmin Wang, Sandra Moreno   +3 more
wiley   +1 more source

Intrauterine Transplantation of Isogenic Pancreatic Islets in Experimental Diabetic Rats.

Journal of Veterinary Medical Science, 1994
The effect of intrauterine transplantation (IU group) as a potential immunologically privileged site on the diabetic state of the recipient was compared with that of conventional intraperitoneal transplantation (IP group) using Fisher 344 rats. Islets were isolated from the pancreata of normal rats and transplanted into the uterus and peritoneal cavity
I, Sakonju, Y, Taura, M, Nakaichi, S, Nakama, S, Kagabu   +4 more
openaire   +3 more sources

Transplante isogênico de ilhotas de Langerhans no fígado de ratos: metodologia para separação e purificação das ilhotas de Langerhans Isogenic islet transplantation on the rat liver: Method for isolation and purification of the rat islets

Arquivos de Gastroenterologia, 2000
A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina mantendo os níveis glicêmicos dentro da normalidade.
Eleazar CHAIB, Apostolos PAPALOIS, Ingrid G. M. BRONS, Roy Y. CALNE   +3 more
doaj   +1 more source

Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF‐α‐Smurf1‐Akt‐mTOR‐P70S6K pathway

Journal of Cellular and Molecular Medicine, Volume 23, Issue 8, Page 5390-5402, August 2019., 2019
Abstract Allograft interstitial fibrosis was characterized by massive extracellular matrix deposition caused by activated fibroblasts and myofibroblasts. Epithelial‐mesenchymal transition (EMT) is recognized as an important source of myofibroblasts contributing to the pathogenesis of allograft interstitial fibrosis.
Jiajun Zhou, Hong Cheng, Zijie Wang, Hao Chen, Chuanjian Suo, Hengcheng Zhang, Jiayi Zhang, Yanhao Yang, Liang Geng, Ming Gu, Ruoyun Tan   +10 more
wiley   +1 more source

Effects of Iso and Xeno Fetal Liver Fragments Transplantation on Acute and Chronic Liver Failure in Rats

Cell Transplantation, 1994
Isogeneic (rat) and xenogeneic (swine) fetal liver fragments (FLF) transplantation into the omentum was performed for d-galactosamine (d-Gal)-induced acute and carbon tetrachloride (CCI 4 )-induced chronic hepatic failure in rats. The recipients that had
M. Hagihara, T. Shimura, K. Takebe, B. Munkhbat, K. Tsuji   +4 more
doaj   +1 more source

Renal Allograft Rejection: Noninvasive Ultrasound‐ and MRI‐Based Diagnostics

Contrast Media &Molecular Imaging, Volume 2019, Issue 1, 2019., 2019
To date, allogeneic kidney transplantation remains the best available therapeutic option for patients with end‐stage renal disease regarding overall survival and quality of life. Despite the advancements in immunosuppressive drugs and protocols, episodes of acute allograft rejection, a sterile inflammatory process, continue to endanger allograft ...
Ulrich Jehn, Katharina Schuette-Nuetgen, Dominik Kentrup, Verena Hoerr, Stefan Reuter, Sarah Ohrndorf   +5 more
wiley   +1 more source

Storage and allogeneic transplantation of peripheral nerve using a green tea polyphenol solution in a canine model

Journal of Brachial Plexus and Peripheral Nerve Injury, 2010
Background In our previous study, allogeneic-transplanted peripheral nerve segments preserved for one month in a polyphenol solution at 4°C could regenerate nerves in rodents demonstrated the same extent of nerve regeneration as isogeneic fresh nerve ...
Noguchi Takashi, Fujita Satoshi, Ohta Soichi, Yamakawa Tomoyuki, Ikeguchi Ryosuke, Kakinoki Ryosuke, Nakayama Ken, Duncan Scott FM, Hyon Suong-Hyu, Nakamura Takashi   +9 more
doaj   +1 more source