Results 21 to 30 of about 1,229,293 (285)

Diffuse axonal injury predicts neurodegeneration after moderate–severe traumatic brain injury [PDF]

, 2020
Traumatic brain injury is associated with elevated rates of neurodegenerative diseases such as Alzheimer’s disease and chronic traumatic encephalopathy. In experimental models, diffuse axonal injury triggers post-traumatic neurodegeneration, with axonal ...
Bourke, NJ, Schott, JM, Graham, NSN, Jolly, A, Cole, JH, Scott, G, Zimmerman, K, Sharp, DJ   +7 more
core   +2 more sources

White matter damage and cognitive impairment after traumatic brain injury [PDF]

, 2010
White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent.
Powell, Jane Hilary, Leech, R, K. M. Kinnunen, Counsell, Serena Jane; id_orcid, Bonnelle, V., Sharp, D. J., Kinnunen, K. M., Hawkins, Peter Charlie; id_orcid, Patel, Maneesh Chandrakant, Patel, MC, M. C. Patel, Sharp, David James, Greenwood, Richard, D. J. Sharp, Hawkins, PC, Leech, R., Patel, M. C., Powell, Jane H., Greenwood, R, J. H. Powell, Counsell, S. J., Sharp, DJ, P. C. Hawkins, Counsell, SJ, Powell, JH, R. Greenwood, Kinnunen, KM, R. Leech, Bonnelle, Valerie, Leech, Robert, V. Bonnelle, Kinnunen, Kirsi Maria, Hawkins, R. C., S. J. Counsell   +33 more
core   +1 more source

Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments

Frontiers in Cellular Neuroscience, 2014
Traumatic brain injury from penetrating or closed forces to the cranium can result in a range of forms of neural damage, which culminate in mortality or impart mild to significant neurological disability.
Declan Guenter Siedler, Declan Guenter Siedler, Meng Inn Chuah, Meng Inn Chuah, Matthew T.K. Kirkcaldie, Matthew T.K. Kirkcaldie, James C Vickers, James C Vickers, Anna eKing, Anna eKing   +9 more
doaj   +1 more source

Ballooned neurons in semi-recent severe traumatic brain injury

Acta Neuropathologica Communications, 2023
Traumatic brain injury (TBI) is now recognized as an insult triggering a dynamic process of degeneration and regeneration potentially evolving for years with chronic traumatic encephalopathy (CTE) as one major complication.
Jean Michaud, Isabelle Plu, Jacqueline Parai, André Bourgault, Caroline Tanguay, Danielle Seilhean, John Woulfe   +6 more
doaj   +1 more source

Behavioral Deficits and Axonal Injury Persistence after Rotational Head Injury Are Direction Dependent [PDF]

, 2013
Pigs continue to grow in importance as a tool in neuroscience. However, behavioral tests that have been validated in the rodent model do not translate well to pigs because of their very different responses to behavioral stimuli.
Propert, Kathleen J, Sullivan, Sarah, Friess, Stuart H, Smith, Colin; id_orcid, Margulies, Susan S, Rapp, Paul E, Ralston, Jill   +6 more
core   +1 more source

Purkinje cell vulnerability induced by diffuse traumatic brain injury is linked to disruption of long-range neuronal circuits

Acta Neuropathologica Communications, 2022
Cerebellar dysfunction is commonly observed following traumatic brain injury (TBI). While direct impact to the cerebellum by TBI is rare, cerebellar pathology may be caused by indirect injury via cortico-cerebellar pathways.
Ilknur Özen, Hongcheng Mai, Alessandro De Maio, Karsten Ruscher, Georgios Michalettos, Fredrik Clausen, Michael Gottschalk, Saema Ansar, Sertan Arkan, Ali Erturk, Niklas Marklund   +10 more
doaj   +1 more source

Prognosis of diffuse axonal injury with traumatic brain injury [PDF]

Journal of Trauma and Acute Care Surgery, 2018
BACKGROUND Determine the prognostic impact of magnetic resonance imaging (MRI)-defined diffuse axonal injury (DAI) after traumatic brain injury (TBI) on functional outcomes, quality of life, and 3-year mortality. METHODS This retrospective single center cohort included adult trauma ...
Stephen S, Humble, Laura D, Wilson, Li, Wang, Drew A, Long, Miya A, Smith, Jonathan C, Siktberg, Mina F, Mirhoseini, Aashim, Bhatia, Sumit, Pruthi, Matthew A, Day, Susanne, Muehlschlegel, Mayur B, Patel   +11 more
openaire   +2 more sources

Neurological consequences of traumatic brain injuries in sports. [PDF]

, 2015
Traumatic brain injury (TBI) is common in boxing and other contact sports. The long term irreversible and progressive aftermath of TBI in boxers depicted as punch drunk syndrome was described almost a century ago and is now widely referred as chronic ...
Zetterberg, H, Ling, Helen, Zetterberg, Henrik,, Ling, H, Hardy, J, Hardy, John   +5 more
core   +1 more source

Damage to Myelin and Oligodendrocytes: A Role in Chronic Outcomes Following Traumatic Brain Injury?

Brain Sciences, 2013
There is increasing evidence in the experimental and clinical traumatic brain injury (TBI) literature that loss of central myelinated nerve fibers continues over the chronic post-traumatic phase after injury.
William L. Maxwell
doaj   +1 more source

Folic Acid Enhances Early Functional Recovery in a Piglet Model of Pediatric Head Injury [PDF]

, 2010
For stroke and spinal cord injury, folic acid supplementation has been shown to enhance neurodevelopment and to provide neuroprotection. We hypothesized that folic acid would reduce brain injury and improve neurological outcome in a neonatal piglet model
Jill Ralston, Friess, Stuart, Susan S. Margulies, Naim, Maryam Y., Colin Smith, Helfaer, Mark A., Maryam Y. Naim, Karen Ryall, Ryall, Karen, Margulies, Susan S., Smith, Colin; id_orcid, Mark A. Helfaer, Ralston, Jill, Stuart Friess   +13 more
core   +1 more source