Results 51 to 60 of about 1,229,293 (285)

Current contribution of diffusion tensor imaging in the evaluation of diffuse axonal injury

Arquivos de Neuro-Psiquiatria
Traumatic brain injury (TBI) is the number one cause of death and morbidity among young adults. Moreover, survivors are frequently left with functional disabilities during the most productive years of their lives.
Daphine Centola Grassi, David Macedo da Conceição, Claudia da Costa Leite, Celi Santos Andrade   +3 more
doaj   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon

Neurobiology of Disease, 2013
Axonal injury and degeneration, whether primary or secondary, contribute to the morbidity and mortality seen in many acquired and inherited central nervous system (CNS) and peripheral nervous system (PNS) disorders, such as traumatic brain injury, spinal
Marek Ma
doaj   +1 more source

Axonal Response to Traumatic Brain Injury: Reactive Axonal Change, Deafferentation, and Neuroplasticity

, 1992
Axonal injury appears to be a feature common to all traumatic brain injuries, and has been linked to much of the morbidity seen in head-injured patients.
Daniel E. Erb, John T. Povlishock, Juan Astruc   +2 more
core   +1 more source

Social behavior following traumatic brain injury and its association with emotion recognition, understanding of intentions, and cognitive flexibility. [PDF]

, 2008
Although the adverse consequences of changes in social behavior following traumatic brain injury (TBI) are well documented, relatively little is known about possible underlying neuropsychological deficits.
Crawford, John R, Ietswaart, Magdalena, MAGDALENA IETSWAART, Milders, Maarten, Crawford, John R., JOHN R. CRAWFORD, Currie, David, MAARTEN MILDERS, DAVID CURRIE   +8 more
core   +1 more source

Evaluating the effect of post-traumatic hypoxia on the development of axonal injury following traumatic brain injury in sheep [PDF]

, 2023
Damage to the axonal white matter tracts within the brain is a key cause of neurological impairment and longterm disability following traumatic brain injury (TBI).
Quarrington, R.D., Kaukas, L., Sharkey, J.M., Krieg, J.L., Jones, C.F., Corrigan, F., Turner, R.J., Leonard, A.   +7 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Neuropsychological, functional and behavioural outcome and predictors of outcome in a sample of traumatic brain injury litigants [PDF]

, 2008
Includes abstract.Includes bibliographical references (leaves 147-162).Generally, this study aimed to explore whether financial settlement in litigation influences outcome and recovery from closed head injury in a sample of traumatic brain injured (TBI ...
Gouse, Hetta
core   +1 more source

Placebo-controlled trial of oral amantadine and zolpidem efficacy on the outcome of patients with acute severe traumatic brain injury and diffuse axonal injury

Caspian Journal of Internal Medicine, 2022
Background: A constituent of diffuse axonal injury (DAI) is supposed to be present in about 1/3 of all severe traumatic brain injury (TBI) as specified by pathologic documents.
sajad shafiee, Saeed Ehteshami, Mahmoodd Moosazadeh, Saeed Aghapour, Kaveh Haddadi   +4 more
doaj