Results 61 to 70 of about 8,613,368 (310)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM) : study protocol for a randomized controlled trial [PDF]

, 2014
Background In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated ...
Squire, Stephen Bertel, Squire, S Bertel, Patrick PJ Phillips, Madan, Jason, Rusen, I. D., Chiang, Chen-Yuan, Armand Van Deun, Chiang, Chen Yuan, Gabriela Torrea, Phillips, P. (Patrick), Van Deun, Armand, Rusen, ID, Meredith, Sarah K, Jason Madan, Meredith, Sarah K., Nunn, Andrew J, ID Rusen, Nunn, Andrew J., Squire, Bertie, Torrea, Gabriela, Chen-Yuan Chiang, Sarah K Meredith, Phillips, Patrick PJ, Andrew J Nunn, Phillips, Patrick P.J., S Bertel Squire   +25 more
core   +2 more sources

The Role of Astrocytes in the Molecular Pathophysiology of Schizophrenia: Between Neurodevelopment and Neurodegeneration

Biomolecules
Schizophrenia is a chronic and severe psychiatric disorder affecting approximately 1% of the global population, characterized by disrupted synaptic plasticity and brain connectivity.
Licia Vellucci, Benedetta Mazza, Annarita Barone, Anita Nasti, Giuseppe De Simone, Felice Iasevoli, Andrea de Bartolomeis   +6 more
doaj   +1 more source

Treatment Resistant Hypertension

Ethnicity & Disease, 2015
<p>Treatment resistant hypertension (TRH) is defined by office blood pressure (BP) uncontrolled on ≥3 or controlled on ≥4 antihypertensive medications, preferably at optimal doses and including a diuretic. Apparent (a)TRH is used when optimal therapy, adherence, and measurement artifacts are unknown.
openaire   +3 more sources

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Hepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trials [PDF]

, 2012
Background: In patients with genotype 1 chronic hepatitis C infection, telaprevir (TVR) in combination with peginterferon and ribavirin (PR) significantly increased sustained virologic response (SVR) rates compared with PR alone.
Bambang Adiwijaya, Joan Spanks, Ann Tigges (171451), Ann Tigges, Joan Spanks (171460), Zhang Eileen Z., Maria Beumont, Bartels Doug J., De Meyer, Sandra, Jacobson, Ira M., Ira M. Jacobson (171497), Kieffer Tara L., Ghys Anne, Min Jiang, Sullivan James C., James C Sullivan, Doug J Bartels, Beumont, Maria, Dorrian Jennifer, Dierynck, Inge, Nathalie Adda, Adiwijaya, Bambang, Kauffman, Robert S., Kwong, Ann D., Min Jiang (56794), Jennifer Dorrian (171464), James C. Sullivan (13811), Bambang Adiwijaya (171470), Sherman, Kenneth E., Dierynck Inge, Ann D. Kwong (171515), Ghys, Anne, Tara L Kieffer, Gaston Picchio, Maria Beumont (171481), Spanks Joan, Inge Dierynck, Kenneth E Sherman, Robert S Kauffman, Adda Nathalie, Sherman Kenneth E., Stefan Zeuzem (22856), Stefan Zeuzem, Inge Dierynck (171456), Jiang, Min, Robert S. Kauffman (171487), Gaston Picchio (171523), Kwong Ann D., Zhang, Eileen Z., Sandra De Meyer (171427), Tigges, Ann, Zeuzem Stefan, Dorrian, Jennifer, Kenneth E. Sherman (171505), Sandra De Meyer, Nathalie Adda (171493), Jacobson Ira M., Adiwijaya Bambang, Ira M Jacobson, Bartels, Doug J., Doug J. Bartels (171434), Eileen Z Zhang, Jennifer Dorrian, De Meyer Sandra, Tigges Ann, Sullivan, James C., Picchio, Gaston, Ann D Kwong, Anne Ghys (171476), Adda, Nathalie, Eileen Z. Zhang (171445), Kieffer, Tara L., Spanks, Joan, Picchio Gaston, Kauffman Robert S., Anne Ghys, Tara L. Kieffer (171419), Jiang Min, Zeuzem, Stefan, Beumont Maria   +79 more
core   +1 more source

The effectiveness of cognitive behavioral therapy on treatment-resistant depression

Chronic Diseases Journal, 2020
BACKGROUND: Treatment-resistant depression (TRD) is a severe and chronic form of major depression. It poses significant clinical, personal, and economic burden and does not respond to antidepressants. Psychotherapy can be a suggested option.
Rezvan Sadrmohammadi, Simin Gholamrezaei
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Treating cisplatin-resistant cancer: a systematic analysis of oxaliplatin or paclitaxel salvage chemotherapy [PDF]

, 2009
Objective: To examine the pre-clinical and clinical evidence for the use of oxaliplatin or paclitaxel salvage chemotherapy in patients with cisplatin-resistant cancer.
Pavlakis, Nick, Ross Davey, Davey, Ross, Nick Pavlakis, Britta Stordal, Stordal, Britta   +5 more
core   +2 more sources