Results 11 to 20 of about 212,475 (307)

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition [PDF]

open access: yes, 2014
Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage.
A Micheli   +27 more
core   +13 more sources

Regulatory T-cells and allogeneic hematopoietic stem cell transplantation

open access: yesТрансплантология (Москва), 2022
The article has summarized the available data about regulatory T cells, describing in-detail the stages of their studying, their development, classification, mechanisms of immunosuppression in general terms and also in the context of allogeneic ...
O. S. Karavaeva   +2 more
doaj   +1 more source

Tissue Tregs [PDF]

open access: yesAnnual Review of Immunology, 2016
The immune system is responsible for defending an organism against the myriad of microbial invaders it constantly confronts. It has become increasingly clear that the immune system has a second major function: the maintenance of organismal homeostasis. Foxp3+CD4+regulatory T cells (Tregs) are important contributors to both of these critical activities,
Marisella, Panduro   +2 more
openaire   +2 more sources

Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance

open access: yesThe Journal of Reproduction and Development, 2021
Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN   +6 more
doaj   +1 more source

Facilitating Success: Using Self-Regulated Learning and Servant Leadership in the College Classroom

open access: yesJournal of Teaching and Learning with Technology, 2020
Student-centered pedagogy shifts the power dynamics, function of content, role of the educator, responsibility for learning, and purpose of evaluation (Weimer, 2013) within the classroom.
Michelle Lynn Clemons, Treg Hopkins
doaj   +1 more source

LKB1 Positively Regulates Dendritic Cell-induced T Cell Immunity and Suppresses Tumor Development [PDF]

open access: yesIranian Journal of Immunology, 2023
Background: The functions of dendritic cells (DCs) are influenced by their intracellular metabolism, in which liver kinase B1 (LKB1) plays an important role.
Wenjie Zhang   +6 more
doaj   +1 more source

ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases [PDF]

open access: yesFrontiers in Immunology, 2020
Recent studies have reported the pathological effect of ICOS+ T cells, but ICOS signals also widely participate in anti-inflammatory responses, particularly ICOS+ regulatory T (Treg) cells. The ICOS signaling pathway endows Tregs with increased generation, proliferation, and survival abilities.
Dan-Yang Li   +3 more
openaire   +3 more sources

How sphingolipids affect T cells in the resolution of inflammation

open access: yesFrontiers in Pharmacology, 2022
The concept of proper resolution of inflammation rather than counteracting it, gained a lot of attention in the past few years. Re-assembly of tissue and cell homeostasis as well as establishment of adaptive immunity after inflammatory processes are the ...
Jennifer Christina Hartel   +4 more
doaj   +1 more source

Evaluation of the functional activity of CD39 ectonucleotidase in regulatory T cells in children with inflammatory bowel diseases

open access: yesМедицинская иммунология, 2023
In connection with the increasing incidence and prevalence of inflammatory bowel disease (IBD), the search for prognostic markers of the effectiveness of therapy is an urgent problem. An imbalance between Th17 lymphocytes and regulatory T cells (Treg) is
T. V. Radygina   +6 more
doaj   +1 more source

Treg Cells in Ischemic Stroke: A Small Key to a Great Orchestrion [PDF]

open access: yesКлиническая практика, 2023
Ischemic stroke is a global medical problem and one of the leading causes of death or disability worldwide. The main approach of ischemic stroke therapy in the most acute period, which can prevent or minimize the development of a neurological deficit, is
Oksana A. Zhukova   +5 more
doaj   +1 more source

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