Results 11 to 20 of about 4,874,341 (306)
The role of Treg cells in colorectal cancer and the immunotherapy targeting Treg cells [PDF]
Frontiers in ImmunologyColorectal cancer (CRC) is among the most prevalent and lethal cancers globally, accounting for approximately 10% of all cancer cases and deaths. Regulatory T (Treg) cells, which accumulate in CRC tissue, suppress anti-tumor immune responses and facilitate tumor progression.
Hanqing Yu +4 more
openaire +4 more sources
Isolation Of Treg Cells And Treg Cell Suppression/Death Assay
, 2015 In vitro Treg suppression assays are performed to determine the functional effect of Treg cells on CD4 T cells. They are performed by co-culturing the responding population (Tresp) with the Treg cells or control CD4 cells (Tcon cells).
sprotocols
openaire +2 more sources
Adoptive Transfer of Treg Cells Combined with Mesenchymal Stem Cells Facilitates Repopulation of Endogenous Treg Cells in a Murine Acute GVHD Model. [PDF]
PLoS ONE, 2015 Therapeutic effects of combined cell therapy with mesenchymal stem cells (MSCs) and regulatory T cells (Treg cells) have recently been studied in acute graft-versus-host-disease (aGVHD) models.
Eun-Sol Lee +6 more
doaj +2 more sources
Nanotechnology as a New Therapeutic Approach to Prevent the HIV-Infection of Treg Cells. [PDF]
PLoS ONE, 2016 BACKGROUND:HIV-1 has proved to infect regulatory T cells (Treg) modifying their phenotype and impairing their suppressive capacity. As Treg cells are a crucial component in the preservation of the immune homeostasis, we researched that the antiviral ...
Didiana Jaramillo-Ruiz +4 more
doaj +3 more sources
Fragile Treg cells: Traitors in immune homeostasis?
Pharmacological ResearchRegulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue homeostasis. However, in some disease microenvironments, Treg cells exhibit fragility, which manifests as preserved FoxP3 expression accompanied by inflammation and loss
Xiyu Song +7 more
doaj +2 more sources
Treg-NASHcm and HFMCDm increased the inflammasome and inhibited the proliferative H9c2 cells.
, 2022 Flow cytometry-assessed relative intracellular levels (/buffer group) of (A) FXR, IL-10R, IL-10, (B) NLRP3, caspase-1 among various CM pre-treated H9c2. Bar graph of (C) immunofluorescence-assessed Ki-67+cells (red color), TUNEL+ cells (green color), and
Tzu-Hao Li (2183854) +7 more
core +1 more source
Characterization of lymph node stromal cells during Treg-mediated tolerance [PDF]
, 2013 Solid organs transplantation is therapy of choice for several human diseases. The success of this treatment is determined by the recipientÕs ability to prevent rejection.
Broggi, Maria Anna Sofia
core +1 more source
Treg cells to the rescue [PDF]
Arthritis & Rheumatism, 2012 In this issue of Arthritis & Rheumatism, Kong and colleagues report that collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA), can be effectively treated by systemic injection of Treg cells (1). These results raise several questions: Are there defects in Treg cell numbers or function in RA?
openaire +3 more sources
Cell Reports, 2020 Summary: Regulatory T (Treg) cells integrate diverse environmental signals to modulate their function for optimal suppression. Translational regulation represents a favorable mechanism for Treg cell environmental sensing and adaptation. In this study, we
Yujian H. Yang +9 more
doaj +1 more source
Frontiers in Immunology, 2021 FOXP3+ regulatory T cells (Treg cells) are a specialized population of CD4+ T cells that restrict immune activation and are essential to prevent systemic autoimmunity.
Justin Jacobse +11 more
doaj +1 more source