Results 31 to 40 of about 12,132,339 (300)
Turning the Tide Against Regulatory T Cells
Frontiers in Oncology, 2019 Regulatory T (Treg) cells play crucial roles in health and disease through their immunosuppressive properties against various immune cells. In this review we will focus on the inhibitory role of Treg cells in anti-tumor immunity.
SeongJun Han +7 more
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Treg cells to the rescue [PDF]
Arthritis & Rheumatism, 2012 In this issue of Arthritis & Rheumatism, Kong and colleagues report that collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA), can be effectively treated by systemic injection of Treg cells (1). These results raise several questions: Are there defects in Treg cell numbers or function in RA?
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The Balance of Th17 versus Treg Cells in Autoimmunity
International Journal of Molecular Sciences, 2018 T helper type 17 (Th17) cells and pTreg cells, which share a common precursor cell (the naïve CD4 T cell), require a common tumor growth factor (TGF)-β signal for initial differentiation.
G. Lee
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Nanotechnology as a New Therapeutic Approach to Prevent the HIV-Infection of Treg Cells. [PDF]
PLoS ONE, 2016 BACKGROUND:HIV-1 has proved to infect regulatory T cells (Treg) modifying their phenotype and impairing their suppressive capacity. As Treg cells are a crucial component in the preservation of the immune homeostasis, we researched that the antiviral ...
Didiana Jaramillo-Ruiz +4 more
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Journal of Immunology Research, 2014 Regulatory T (Treg) cells are potent suppressors that maintain immune homeostasis. Accumulation of Treg can inhibit effective immune responses in cancer patients, leading to tumor development and progression.
Jie-Yao Li +12 more
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Expression of IL-37 Induces a Regulatory T-Cell-like Phenotype and Function in Jurkat Cells
Cells, 2022 The anti-inflammatory cytokine interleukin-37 (IL-37) plays a key role in inhibiting innate and adaptive immunity. Past results have shown that IL-37 is elevated in human Treg cells compared to other T cell subsets and contributes to enhancing the Treg ...
Douglas Grant Osborne +2 more
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iScience, 2022 Summary: Overwhelming evidence indicates that infiltration of tumors by Treg cells with elevated levels of FOXP3 suppresses the host antitumor immune response. However, the molecular mechanisms that maintain high expression of FOXP3 in tumor-infiltrating
Junqing An +7 more
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The Imbalance of FOXP3/GATA3 in Regulatory T Cells from the Peripheral Blood of Asthmatic Patients
Journal of Immunology Research, 2018 Background. Treg cells play an important role in the pathogenic progress of asthma. Objective. To address the alterations of Treg cells in asthma. Methods.
Tiantian Chen +6 more
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The role of thymus- and extrathymus-derived regulatory T cells in maternal-fetal tolerance
Frontiers in Immunology, 2023 Regulatory T (Treg) cells could be divided into thymus-derived Treg (tTreg) cells and peripherally derived Treg (pTreg) cells, and in vitro induced Treg (iTreg) cells.
Zhengjuan Li +7 more
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Treg Cells, Life History, and Diversity [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 Regulatory T cells expressing the FoxP3 transcription factor have a profound and nonredundant role in several aspects of immunological tolerance. We will review here the specification of this lineage, its population dynamics, and the diversity of subphenotypes that correlate with their diverse roles in controlling inflammation in a variety of settings.
Christophe, Benoist, Diane, Mathis
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