Results 131 to 140 of about 93,800 (248)

BCG enriches Treg cells [PDF]

Nature Reviews Urology, 2018
openaire   +2 more sources

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

The double-edged sword of regulatory T cells in MASLD: from inflammation control to fibrosis promotion. [PDF]

Anim Cells Syst (Seoul)
Lee SE, Jo MG, Park SW, Kim HJ, Yun SP, Kim JW.   +5 more
europepmc   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

Regulatory T cells in hypoxic environments. [PDF]

Front Immunol
González-Rivera L, Luna-Gutiérrez R, Cárdenas S, Merino-González C, Handy A, Pepper I, López MN.   +6 more
europepmc   +1 more source

Immunomodulatory Fibrous Scaffold with Dual Enzyme‐Mimic Activities Prevents Postsurgical Tumor Recurrence

Advanced Science, EarlyView.
A MnOx nanozyme‐functionalized electrospun fibrous scaffold is developed for postoperative therapy by leveraging its intrinsic physicochemical and immunomodulatory properties. Integrating POD‐ and CAT‐like activities, the scaffold induces immunogenic cell death, alleviates hypoxia, and reverses immunosuppression, while simultaneously recruiting and ...
Xiaoyi Zhao, Zhuolong Jiao, Yue Wang, Huimeng Gu, Longfei Li, Jian Song, Chen Xu, Jiajia Xue, Fu‐Jian Xu, Nana Zhao   +9 more
wiley   +1 more source

Specific depletion of TIGIT^high CD226^- clonally expanded intratumoral Tregs defines safe and effective TIGIT targeting. [PDF]

J Immunother Cancer
Zhou H, Li J, Mei S, Zhang M, Zhao H, Yan K, Cheng Y, Zhou Q, Zheng P, Liu Y, Zhang P, Li H, Lu W, Zhang Y.   +13 more
europepmc   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Editorial: The Spectrum of Treg Subsets in Transplantation: Immune Regulation and Tolerance Induction

Frontiers in Immunology, 2022
Mousa Mohammadnia-Afrouzi, Mousa Mohammadnia-Afrouzi, Mohammad Mirzakhani, Mohammad Mirzakhani, Mehdi Shahbazi, Mehdi Shahbazi, Iuliia Kotko, Hans-Dieter Volk   +7 more
doaj   +1 more source

The role of miRNAs in the development of Super-Tregs as a potential therapy for neurodegenerative diseases. [PDF]

Front Immunol
Mukherjee K, Bhattacharyya SN.
europepmc   +1 more source