Results 131 to 140 of about 130,982 (298)
Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon+25 more
wiley +1 more source
Peripheral CD4+CD25+ regulatory T cells (Treg) block alloreactive host anti-donor T cells in canine mixed hematopoietic chimeras [PDF]
Marina Lesnikova+4 more
openalex +1 more source
Distinct Role of IL-27 in Immature and LPS-Induced Mature Dendritic Cell-Mediated Development of CD4 [PDF]
Interleukin-27 (IL-27) plays an important role in regulation of anti-inflammatory responses and autoimmunity; however, the molecular mechanisms of IL-27 in modulation of immune tolerance and autoimmunity have not been fully elucidated.
Rostami, A. M.+2 more
core +1 more source
Prostate and bladder cancers activate genes and pathways similar to those in the developmental stage by aggregating and analyzing current data. In this process, sex hormones and their receptors maybe a key role in causing and reversing the “cold” and “hot” immune tumor phenotypes, potentially enhancing the immune response.
Dengxiong Li+16 more
wiley +1 more source
Targeting mesothelin (MSLN) improved neoantigen vaccine efficacy in pancreatic cancer by reducing apCAFs, which disrupted the conversion of naive CD4+ T cells into Tregs and enhanced the infiltration of IFN‐γ+CD4+ and GZMK+CD8+ T cells. This combination strengthened neoantigen‐specific T cell response to overcome the immunosuppressive tumor ...
Zhixiong Cai+11 more
wiley +1 more source
Regulatory T cell (Treg) reconstitution following T cell depleted allogeneic stem cell transplantation—kinetics of recovery and relationship with GVHD [PDF]
Katayoun Rezvani+7 more
openalex +1 more source
A supramolecular modulation of tumor microenvironment is proposed to potentiate cancer chemoimmunotherapy. Based on metal coordination, DACHPt is tailor‐encapsulated into SNPs and evokes an antitumor immune response in the case of a potent chemotherapeutical effect.
Dan Wu+7 more
wiley +1 more source
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu+7 more
wiley +1 more source