Results 221 to 230 of about 157,767 (395)

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman, Pablo Duarte, Esteban Dauden, Antonio Cuadrado, María Isabel Rodríguez‐Franco, Manuela G. López, Rafael León   +6 more
wiley   +1 more source

Combating oxi-inflamm-aging: Passerini adducts tethered with 1,2,3-triazoles for enhanced antioxidant defense and 5-LOX inhibition. [PDF]

RSC Med Chem
Ayoup MS, Rashwan MM, Soliman SM, Ghareeb DA, Ashraf S, Ismail MMF, Tageldin GN, Sonousi A, Awad LF.   +8 more
europepmc   +1 more source

Spectrophotometric determination of iron with 3-(2-hydroxypheny1)-1H-1, 2, 4-triazole

, 1963
Atsushi Sugii, Hideo SUMIE
openalex   +2 more sources

Complexing Behaviour of 2H-1,2,4-Triazole-3-thiol Complexes of Co(II), Ni(II), Cu(II), Ru(II), Rh(III), Pd(II), Pt(II), and Au(I) [PDF]

, 1978
B. K. Sen Gupta, D. S. Gupta, U. G. Agarwala   +2 more
openalex   +1 more source

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions

Chemistry – A European Journal, EarlyView.
Highly water‐soluble Npy‐sulfenate functions as an efficient oxidizing agent for the formation of disulfide bonds in thiol‐containing peptides. The Npy‐sulfenate can be used to form a disulfide bond with a thiol‐containing peptide produced by thiol‐additive‐free NCL, thereby facilitating the one‐pot synthesis of adrenomedullin.
Akihiro Taguchi, Megumi Sakata, Ryusei Yamamoto, Hayate Shida, Saeka Kuraishi, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi   +8 more
wiley   +1 more source

Structural and Mechanistic Insights into Atypical Bacterial Topoisomerase Inhibitors. [PDF]

ACS Med Chem Lett
Toth PD, Ratigan SC, Powell JW, Cassel SR, Yalowich JC, McElroy CA, Lindert S, Bell CE, Mitton-Fry MJ.   +8 more
europepmc   +1 more source

Mass spectra of 1,2,4-triazoles: A novel skeletal rearrangement [PDF]

, 1975
R. Krishna Mohan Rao Kallury, T. G. SURENDRA NATH, VR Srinivasan   +2 more
openalex   +1 more source

A Copper(I) Catenane Decorated Metal‐Organic Layer as a Heterogenous Catalyst for Dehydrogenative Cross‐Coupling

Chemistry – A European Journal, EarlyView.
Reported in this work is a metal‐organic layer decorated with a 2D array of catalytically active Cu(I) catenanes for dehydrogenative C─O coupling. Kinetic stabilization effects from the interlocked ligands not only preserve the structural integrity of the molecular Cu(I) catalyst for a straightforward attachment onto the solid support, but also ...
Yi‐Xiang Shi, Lihui Zhu, Hoai Son Doan, Yulin Deng, Xiaoyong Mo, Yufeng Wang, Edmund C. M. Tse, Ho Yu Au‐Yeung   +7 more
wiley   +1 more source

Design and synthesis of new 1,2,3-triazole-methoxyphenyl-1,3,4-oxadiazole derivatives: selective butyrylcholinesterase inhibitors against Alzheimer's disease. [PDF]

BMC Chem
Iraji A, Hariri R, Hashempur MH, Ghasemi M, Pourtaher H, Saeedi M, Akbarzadeh T.   +6 more
europepmc   +1 more source

1, 2, 4-Triazoles. III. The Tautomerism of 3-Phenyl-1, 2, 4-triazolin-5-one, 3-Phenyl-1, 2, 4-triazoline-5-thione and Their N-Methyl Derivatives

, 1973
Seiju Kubota, Masayuki Uda
openalex   +2 more sources