Results 211 to 220 of about 103,024 (350)

Synthesis of 1-Fluoroalkyl-5-Substituted-1,2,3-Triazoles from Carbonyl-Stabilized Phosphonium Ylides. [PDF]

open access: yesJ Org Chem
Tichý D   +5 more
europepmc   +1 more source

Flow Chemistry Meets Green Solvents: Telescoped Synthesis of Triazolyl Phosphoramidates and Phosphinamides in γ‐Valerolactone

open access: yesChemSusChem, Volume 19, Issue 9, 14 May 2026.
A telescoped three‐step continuous flow process enables the synthesis of organophosphorus 1,2,3‐triazoles in the biomass‐derived solvent γ‐valerolactone (GVL). The sequence integrates N‐phosphorylation, azidation, and Cu(I)‐catalyzed azide–alkyne cycloaddition (CuAAC), followed by in‐line copper removal, giving diverse triazoles in good to high overall
Viktória Gerő   +3 more
wiley   +1 more source

Synthesis and Pharmacological Evaluation of Novel 1,5-Disubstituted-3-amino-1,2,4-triazoles Designed as Multitarget Directed Ligands for Alzheimer's Disease Targets. [PDF]

open access: yesACS Omega
Franco DP   +10 more
europepmc   +1 more source

Desymmetrization of Pseudo‐para Diformyl[2.2]Paracyclophane via Brønsted Acid‐Catalyzed Reductive Amination

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
A highly stereoselective desymmetrization of pseudo‐para diformyl[2.2]paracyclophanes is developed via chiral Brønsted acid‐catalyzed reductive amination. This protocol provides efficient access to enantiopure planar chiral paracyclophanes with broad substrate scope, excellent enantioselectivity, and versatile postsynthetic functionalization. Access to
Sandip Baban Shinde   +4 more
wiley   +1 more source

Evolution of cross-resistance to medical triazoles in Aspergillus fumigatus through selection pressure of environmental fungicides

open access: yesProceedings of the Royal Society B: Biological Sciences, 2017
Jianhua Zhang   +6 more
semanticscholar   +1 more source

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo   +8 more
wiley   +1 more source

Switchable pathways of multicomponent heterocyclizations of 5-amino-1,2,4-triazoles with salicylaldehydes and pyruvic acid. [PDF]

open access: yesBeilstein J Org Chem
Sakhno YI   +5 more
europepmc   +1 more source

Acute Eruption in a Child With Acute Lymphoblastic Leukemia

open access: yes
Pediatric Dermatology, EarlyView.
L. Parra‐Navarro   +2 more
wiley   +1 more source

Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park   +7 more
wiley   +1 more source

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