Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg +10 more
wiley +1 more source
Deciphering the multidrug resistance paradigm in <i>Candida auris</i>. [PDF]
Santana DJ +3 more
europepmc +1 more source
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia +12 more
wiley +1 more source
Disseminated Phaeohyphomycosis Due to <i>Alternaria alternata</i> in a Liver Transplant Recipient: Successful Treatment With Isavuconazole, a Case Report and Literature Review. [PDF]
Tapia-Villacis S +3 more
europepmc +1 more source
The key cytochrome P450 gene GmSUR2a enables soybeans to withstand destructive submergence stress. By lowering the level of the plant hormone indole‐3‐acetic acid, this gene improves soybean survival and increases field yield. It offers an important tool for breeding stress‑resilient soybeans, securing food production against extreme weather conditions.
Yangyang Chen +14 more
wiley +1 more source
Retraction Note: New Acetamidine Cu(II) Schiff base complex supported on magnetic nanoparticles pectin for the synthesis of triazoles using click chemistry. [PDF]
Siuki HK, Kargar PG, Bagherzade G.
europepmc +1 more source
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò +23 more
wiley +1 more source
Structure-Property Correlations in Disubstituted 1,2,3-Triazoles: DFT Insights and Photophysical Analysis. [PDF]
Lakhani D +9 more
europepmc +1 more source
Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed +1 more
wiley +1 more source
Novel C3/C28-bis-1,2,4-Triazolyl-sulfanylacetate-betulin Derivatives: Synthesis and Evaluation of Anticancer Potential. [PDF]
Prodea A +9 more
europepmc +1 more source

