Results 251 to 260 of about 49,489 (310)

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

A Terpyridine Based 1,2,3‐Triazol‐1,4‐diyl‐Fluoroionophore‐A Fluorometric Study Towards 3d Metal Ions in Acetonitrile

ChemistryOpen, EarlyView.
We synthesized the 1,2,3‐triazol‐1,4‐diyl‐fluoroionophore 1 in a donor(D)‐acceptor(A) arrangement with a 1,2,3‐triazol unit as a π‐linker between a terpyridine (A) ionophore and a diethylaminocoumarin (D) fluorophore to study the fluorescence behavior of 1 towards the divalent 3d metal ions Mn2+, Fe2+, Co2+, Ni2+, Cu2+ and Zn2+. Abstract In this paper,
Thomas Schwarze, Holger Müller, Eric Sperlich, Alexandra Kelling, Hans‐Jürgen Holdt   +4 more
wiley   +1 more source

Node Modification of Metal‐Organic Frameworks for Catalytic Applications

ChemistryOpen, EarlyView.
Post‐synthetic modification of metal‐organic framework (MOF) nodes with metal or organic species produces advanced materials that serve as efficient catalysts, promoting more sustainable chemical transformations. Abstract Metal‐organic frameworks (MOFs) have been a breakthrough in different fields of chemistry, not only due to the extensive ...
Mario Martos, Isidro M. Pastor
wiley   +1 more source

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source

Síntesis de 1,2,3-Triazoles Catalizada por un Complejo Bistriazolli de Cobre (I) [PDF]

, 2013
Cuevas Yañez, Erick, Segura Arzate, Jesús   +1 more
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Development of an Integrated Computational Pipeline for PARP‐1 Inhibitor Screening Using Hybrid Virtual Screening and Molecular Dynamics Simulations

ChemistryOpen, EarlyView.
Poly(ADP‐ribose) polymerase 1 (PARP‐1) is vital for DNA repair. A computational workflow integrating AI‐driven virtual screening (TransFoxMol, KarmaDock, AutoDock Vina) and molecular dynamics identified novel PARP‐1 inhibitors with promising efficacy and minimized side effects.
Guan Wang, Jingjing Guo, Feng Xu, Mingjuan Ji   +3 more
wiley   +1 more source

Estudio de la Síntesis de 1,2,3-Triazoles a partir de la Cicloadición entre Alquinos y Azidas catalizadas por Sales y Complejos de Ag (I) [PDF]

, 2013
Cuevas Yáñez, Erick, Ortega Arizmendi, Aldo Iván   +1 more
core  

Synthesis of Thieno[2,3‐c]pyridine Derivatives by 1,2,3‐Triazole‐Mediated Metal‐Free Denitrogenative Transformation Reaction

ChemistryOpen, EarlyView.
Thieno[2,3‐c]pyridine derivatives are remarkable skeletons in pharmaceutical and material science studies in modern organic chemistry. This article reports the synthesis of 7‐(substituted methyl)thieno[2,3‐c]pyridine, thieno[2,3‐c]pyridine‐7‐ylmethyl ester, and imidazo[1,5‐ɑ]thieno[2,3‐c]pyridine derivatives through denitrogenative transformation via ...
Kumsal Eroğlu, Ömer Tahir Günkara, Wim Dehaen   +2 more
wiley   +1 more source

Penta‐ and Hexacoordinated Copper(II) Complexes with Azido and 4‐amino‐3,5‐di‐2‐pyridyl‐4H‐1,2,4‐triazole Ligands with Field‐Induced Slow Magnetic Relaxation

ChemistryOpen, EarlyView.
A field‐induced slow magnetic relaxation was observed in an ionic pentacoordinated Cu(II) complex with 4‐amino‐3,5‐di‐2‐pyridyl‐4H‐1,2,4‐triazole and azido ligands. The analysis of the relaxation behaviour supports the origin of the slow magnetic relaxation in intramolecular low‐energy vibration modes participating in the one‐phonon direct and two ...
Svitlana Vitushkina, Ivan Potočňák, Oleksandr Bukrynov, Lucia Váhovská, Mariia Holub, Erik Čižmár   +5 more
wiley   +1 more source

Evaluación de la actividad antimicrobiana de triazoles obtenidos por síntesis [PDF]

, 2015
Bethancourt Aguilar, Sergio
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