Results 251 to 260 of about 52,437 (280)
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Synthesis of Triazole Nucleoside Derivatives
Nucleosides, Nucleotides & Nucleic Acids, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Zicheng Li +3 more
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Voriconazole: A New Triazole Antifungal
The Annals of Pharmacotherapy, 2000OBJECTIVE: To review the currently available information on the pharmacology, pharmacokinetics, efficacy, adverse effects, drug interactions, and dosage guidelines of voriconazole. Comparative data for voriconazole and other azole antifungal agents are described where available.
Janelle Sabo, Susan M. Abdel-Rahman
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Pest Management Science, 2012
AbstractAzole resistance is an emerging problem in the opportunistic mould Aspergillus fumigatus. The triazoles are the most important agents for the management of Aspergillus diseases in humans. Selection for acquired resistance may occur in the hospital setting through exposure to high doses of azoles during azole therapy, but evidence is ...
Verweij, P.E. +3 more
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AbstractAzole resistance is an emerging problem in the opportunistic mould Aspergillus fumigatus. The triazoles are the most important agents for the management of Aspergillus diseases in humans. Selection for acquired resistance may occur in the hospital setting through exposure to high doses of azoles during azole therapy, but evidence is ...
Verweij, P.E. +3 more
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Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes
2014Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua +2 more
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2008
Poly(1,2,4-triazole)s (PT)s are heterocyclic polymers, which were first synthesized by the reaction of bistetrazoles and a bisimidoyl chloride. Monomers containing the triazole unit are summarized. Poly(1,2,4-triazole)s can be obtained by the reaction of dinitriles with dihydrazides or by heating cyanocarboxylic acids.
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Poly(1,2,4-triazole)s (PT)s are heterocyclic polymers, which were first synthesized by the reaction of bistetrazoles and a bisimidoyl chloride. Monomers containing the triazole unit are summarized. Poly(1,2,4-triazole)s can be obtained by the reaction of dinitriles with dihydrazides or by heating cyanocarboxylic acids.
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Investigation on inhibition behavior of S-triazole–triazole derivatives in acidic solution
Corrosion Science, 2008Four main methods, such as weight loss test, EIS, adsorption isotherm and quantum chemical calculation were employed to study the inhibition efficiency and mechanism of three derivatives on mild steel in acid solution, whose inhibition efficiency were proved to follow the order of DMTT > NMTT > PMTT, The adsorption model of DMTT was established at ...
Weihua Li +3 more
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1983
Abstract The effects of CGA-64250, a triazole inhibitor of fungal growth, on the lipid composition of Taphrina deformans (D1) were examined using Chromatographic and, in some cases, mass spectrometric techniques. Beginning 8–10 h after inoculation, the total lipid content of cells treated with 0.073 μg/ml averaged 30% more than controls.
John D. Weete +2 more
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Abstract The effects of CGA-64250, a triazole inhibitor of fungal growth, on the lipid composition of Taphrina deformans (D1) were examined using Chromatographic and, in some cases, mass spectrometric techniques. Beginning 8–10 h after inoculation, the total lipid content of cells treated with 0.073 μg/ml averaged 30% more than controls.
John D. Weete +2 more
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Therapeutic drug monitoring for triazoles
Current Opinion in Infectious Diseases, 2008Invasive fungal infections are a leading cause of morbidity and mortality in immunocompromised patients, and mechanisms to optimize therapeutic outcomes are urgently required. Therapeutic drug monitoring represents an important component for the routine use of the triazoles.Triazoles have revolutionized the prevention and treatment of invasive fungal ...
Hope, William W. +3 more
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Synthesis and Characterization of Azido-Functionalized 1,2,3-Triazole and Fused 1,2,3-Triazole
The Journal of Organic Chemistry, 2023Here, we report the nitration of NH on the 1,2,3-triazole ring and the synthesis of several nitrogen-rich energetic compounds based on key intermediate 4-azido-5-(chlorodinitromethyl)-2-nitro-2H-1,2,3-triazole (5). Starting from 4-amino-1H-1,2,3-triazole-5-carbonitrile (1), we successfully constructed compound 5 through four steps.
Yupeng Cao +4 more
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1,2,3‐Triazole and Its Derivatives. Development of Methods for the Formation of the Triazole Ring [PDF]
ChemInform, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Victor P. Krivopalov, Oleg P. Shkurko
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