Results 21 to 30 of about 126,240 (387)
Molecules, 2021 Cu-catalyzed 1,3-dipolar cycloaddition of methyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Suzuki-Miyaura cross-coupling were used to synthesize new triazoles derivatives: 5-aryl-4-arylethynyl-1H-1,2,3-triazoles. Investigation of their optical
Mariia M. Efremova +4 more
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Recent Progress in Catalytic Synthesis of 1,2,3-Triazoles
Catalysts, 2021 1,2,3-triazoles represent a functional heterocyclic core that has been at the center of modern organic chemistry since the beginning of click chemistry. Being a versatile framework, such an aromatic ring can be observed in uncountable molecules useful in
A. De Nino +6 more
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The Overview on the Pharmacokinetic and Pharmacodynamic Interactions of Triazoles
Pharmaceutics, 2021 Second generation triazoles are widely used as first-line drugs for the treatment of invasive fungal infections, including aspergillosis and candidiasis. This class, along with itraconazole, voriconazole, posaconazole, and isavuconazole, is characterized
A. Czyrski +4 more
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5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles
Frontiers in Chemistry, 2020 Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans +3 more
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Synthesis of β-triazolylenones via metal-free desulfonylative alkylation of N-tosyl-1,2,3-triazoles
Beilstein Journal of Organic Chemistry, 2021 Desulfonylative alkylation of N-tosyl-1,2,3-triazoles under metal-free conditions leading to β-triazolylenones is reported here. The present study encompasses the synthesis of triazoles with a new substitution pattern in a single step from cyclic 1,3 ...
Soumyaranjan Pati +3 more
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Application of triazoles in the structural modification of natural products
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Nature products have been extensively used in the discovery and development of new drugs, as the most important source of drugs. The triazole ring is one of main pharmacophore of the nitrogen-containing heterocycles.
Hong-Yan Guo +3 more
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Журнал Белорусского государственного университета: Химия, 2020 The target for antibacterial action of 1,4-di- and 1,4,5-trisubstituted 1H-1,2,3-triazoles against E. coli ATCC 25922 and S. aureus ATCC 6538 was proposed.
Cyril M. Verbilo +4 more
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4,5-Bis(arylethynyl)-1,2,3-triazoles—A New Class of Fluorescent Labels: Synthesis and Applications
Molecules, 2022 Cu-catalyzed 1,3-dipolar cycloaddition of ethyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Sonogashira cross-coupling were used to synthesize a large series of new triazole-based push–pull chromophores: 4,5-bis(arylethynyl)-1H-1,2,3-triazoles ...
Anastasia I. Govdi +7 more
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Molecules, 2021 Green Chemistry has become in the last two decades an increasing part of research interest. Nonconventional «green» sources for chemical reactions include micro-wave, mechanical mixing, visible light and ultrasound.
Lori Gonnet, M. Baron, M. Baltas
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Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents
Molecules, 2023 Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Yaqi Zhao +3 more
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