Behavior of tricellulin during destruction and formation of tight junctions under various extracellular calcium conditions [PDF]
, 2012 Tricellulin is an important component of tricellular tight junctions (TJs) and is involved in the formation of tricellular contacts. However, little is known about its regulation during the assembly and disassembly of tricellular TJs.
Akira Takasawa +6 more
core +1 more source
Allergy, Volume 79, Issue 5, Page 1146-1165, May 2024.Abstract Tight junction (TJ) proteins establish a physical barrier between epithelial cells, playing a crucial role in maintaining tissue homeostasis by safeguarding host tissues against pathogens, allergens, antigens, irritants, etc. Recently, an increasing number of studies have demonstrated that abnormal expression of TJs plays an essential role in ...
Zhi‐Qun Huang +6 more
wiley +1 more source
Cytokine tuning of intestinal epithelial function [PDF]
, 2018 The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies.
Andrews, Caroline +2 more
core +4 more sources
BMC Biology, 2018 Background Mammalian small intestinal tight junctions (TJ) link epithelial cells to one another and function as a permselective barrier, strictly modulating the passage of ions and macromolecules through the pore and leak pathways, respectively, thereby ...
Sarah C. Pearce +8 more
doaj +1 more source
Occludin Content Modulates Hydrogen Peroxide–Induced Increase in Renal Epithelial Paracellular Permeability [PDF]
, 2015 The ability of hydrogen peroxide (H2O2) to increase paracellular permeability of renal epithelial cell monolayers was examined and the role of occludin in this regulation was investigated.
Amsler, Kurt +3 more
core +1 more source
Intestinal preservation using a tailored luminal solution and aeration: A small animal study
Intestinal FailureBackground: Oxygenation during organ preservation has been suggested to enhance outcomes after transplantation, however, data is scarce regarding the intestine. We compared static cold storage (SCS) with two alternative approaches: a luminal polyethylene
Jasmine Bagge +5 more
doaj +1 more source
Structural features of tight-junction proteins [PDF]
, 2019 Tight junctions are complex supramolecular entities composed of integral membrane proteins, membrane-associated and soluble cytoplasmic proteins engaging in an intricate and dynamic system of protein-protein interactions.
Heinemann, U., Schuetz, A.
core +1 more source
Tight junctions: a barrier to the initiation and progression of breast cancer? [PDF]
, 2009 Breast cancer is a complex and heterogeneous disease that arises from epithelial cells lining the breast ducts and lobules. Correct adhesion between adjacent epithelial cells is important in determining the normal structure and function of epithelial ...
Brennan, Kieran +3 more
core +4 more sources
A look at tricellulin and its role in tight junction formation and maintenance
European Journal of Cell Biology, 2011 Tight junctions are elaborate networks of transmembrane and cytosolic proteins that regulate epithelial permeability. Tricellulin was the first tight junction protein found at tricellular tight junctions, the specialized structures occurring where three cells meet together. Here, we summarize the current knowledge about tricellulin (marvelD2), a MARVEL
Cibelle, Mariano +3 more
openaire +2 more sources
Tricellulin: The Role of Tricellulin in Epithelial Jamming and Unjamming via Segmentation of Tricellular Junctions (Adv. Sci. 15/2020) [PDF]
Advanced Science, 2020 Sophie Lohmann +7 more
openaire +1 more source