Results 81 to 90 of about 2,596 (169)

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42

Biology Open, 2015
Immunoglobulin-like domain containing receptor 1 (ILDR1) is a poorly characterized gene that was first identified in lymphoma cells. Mutations in ILDR1 are responsible for DFNB42, but the pathogenesis of hearing loss caused by ILDR1 mutations remains to ...
Qing Sang, Wen Li, Yao Xu, Ronggui Qu, Zhigang Xu, Ruizhi Feng, Li Jin, Lin He, Huawei Li, Lei Wang   +9 more
doaj   +1 more source

Tetraspanin CD9 limits mucosal healing in experimental colitis [PDF]

, 2017
Tetraspanins are a family of proteins with four transmembrane domains that associate between themselves and cluster with other partner proteins, conforming a distinct class of membrane domains, the tetraspanin-enriched microdomains (TEMs).
Arduise, Barreiro, Barreiro, Berditchevski, Boucheix, Cario, Castro-Sanchez, Chami, Charrin, Cooper, Froslie, Fukata, Fukata, Gutiérrez-López, Hemler, Iizuka, Inui, Khor, Kiesler, Kovalenko, Kovalenko, Le Naour, Leung, Mombaerts, Murayama, Natsui, Neurath, Okayasu, Ovalle, Perse, Pineton de Chambrun, Playford, Podolsky, Powner, Rakoff-Nahoum, Rocha-Perugini, Rutgeerts, Shah, Shi, Sinha, Smith, Tai, Tai, Takeda, Tang, Toyo-oka, Williams, Yáñez-Mó   +47 more
core   +4 more sources

Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures.

PLoS ONE, 2019
Ischemic stroke has been shown to induce breakdown of the blood-brain barrier, although these changes are not fully characterized. Oxygen-glucose deprivation (OGD) has been used to investigate the effects of ischemia in cultured brain capillary ...
Erica Tornabene, Hans Christian Cederberg Helms, Stine Falsig Pedersen, Birger Brodin   +3 more
doaj   +1 more source

Effect of cAMP derivates on assembly and maintenance of tight junctions in human umbilical vein endothelial cells

BMC Cell Biology, 2010
Background Endothelial tight and adherens junctions control a variety of physiological processes like adhesion, paracellular transport of solutes or trafficking of activated leukocytes. Formation and maintenance of endothelial junctions largely depend on
Beese Michaela, Wyss Kristin, Haubitz Marion, Kirsch Torsten   +3 more
doaj   +1 more source

Role of the Blood-Brain Barrier in the Formation of Brain Metastases [PDF]

, 2013
The majority of brain metastases originate from lung cancer, breast cancer and malignant melanoma. In order to reach the brain, parenchyma metastatic cells have to transmigrate through the endothelial cell layer of brain capillaries, which forms the ...
Abbott, Ahn, Anfuso, Armulik, Aucoin, Aurrand-Lions, Balda, Barnhill, Bauer, Bos, Brayton, Brightman, Cangara, Carman, Chen, Cohen, Colone, Coussens, Cruz-Munoz, Csilla Fazakas, Cuevas, Daneman, Davies, Dejana, Deli, Denes, Douglas, Duenisch, Fabian, Fan, Farkas, Fidler, Fidler, Furuse, Furuse, Gay, Grinberg-Rashi, Gumbiner, Haskins, Hellstrom, Heon, Hicks, Holland, Hu, Hynes, Ilan, Imola Wilhelm, Inoko, István Krizbai, Izraely, Judit Molnár, János Haskó, Kacem, Khuon, Kienast, Kikuchi, Kim, Kim, Klein, Klein, Konstantopoulos, Krizbai, Krizbai, Krizbai, Krizbai, Krizbai, Lacaz-Vieira, Langer, Langley, Lecht, Lee, Lee, Lee, Li, Lin, Linger, Lockman, Longo, Lorger, Lorger, Lu, Maraveyas, Marchetti, Marchetti, Martin-Padura, Mendes, Mendes, Menter, Mierke, Neuwelt, Nguyen, Nicolson, Nishioku, Nitta, Ohtsuki, Oldendorf, Onodera, Ouban, Paku, Palmieri, Palmieri, Pardridge, Paspalas, Peng, Pestalozzi, Piontek, Platta, Qi, Qi, Reijerkerk, Ridgway, Rolland, Roy, Sahai, Sanz-Moreno, Savettieri, Seike, Shabani, Shimizu, Shintani, Sierra, Sims, Sipos, Stark, Stevenson, Stolp, Takeda, Takenaga, Tester, Tilling, Traweger, Wen, Wilhelm, Wilhelm, Wolburg, Wolf, Wong, Wu, Xie, Yoo, Yoshimasu, Zeljko, Zhang, Zhang, Zohrabian   +144 more
core   +2 more sources

Marked differences in tight junction composition and macromolecular permeability among different intestinal cell types

BMC Biology, 2018
Background Mammalian small intestinal tight junctions (TJ) link epithelial cells to one another and function as a permselective barrier, strictly modulating the passage of ions and macromolecules through the pore and leak pathways, respectively, thereby ...
Sarah C. Pearce, Arwa Al-Jawadi, Kunihiro Kishida, Shiyan Yu, Madeleine Hu, Luke F. Fritzky, Karen L. Edelblum, Nan Gao, Ronaldo P. Ferraris   +8 more
doaj   +1 more source

Tricellulin: The Role of Tricellulin in Epithelial Jamming and Unjamming via Segmentation of Tricellular Junctions (Adv. Sci. 15/2020) [PDF]

Advanced Science, 2020
Sophie Lohmann, Costanza Giampietro, Francesca M. Pramotton, Dunja Al‐Nuaimi, Alessandro Poli, Paolo Maiuri, Dimos Poulikakos, Aldo Ferrari   +7 more
openaire   +1 more source

Occludin Content Modulates Hydrogen Peroxide–Induced Increase in Renal Epithelial Paracellular Permeability [PDF]

, 2015
The ability of hydrogen peroxide (H2O2) to increase paracellular permeability of renal epithelial cell monolayers was examined and the role of occludin in this regulation was investigated.
Amsler, Kurt, Axis, Josephine, Bacallao, Robert L., Janosevic, Danielle   +3 more
core   +1 more source

Intestinal preservation using a tailored luminal solution and aeration: A small animal study

Intestinal Failure
Background: Oxygenation during organ preservation has been suggested to enhance outcomes after transplantation, however, data is scarce regarding the intestine. We compared static cold storage (SCS) with two alternative approaches: a luminal polyethylene
Jasmine Bagge, Arvind Manikantan Padma, Anna Casselbrant, Edina Sehic, Mats Hellström, Mihai Oltean   +5 more
doaj   +1 more source

Studies of the Tumor-Vasculature Interface : Role of TGF-beta 1-induced Epithelial to Mesenchymal Transition [PDF]

, 2013
Tumor metastasis is a complex multistep process. Among key steps that occur during metastatic spread are acquisition of tumor cell motility, intravasation of tumor cells into blood or lymphatic vessels and extravasation of tumor cells at distal sites ...
Pang, Mei-Fong
core   +1 more source