Tricellulin Is Expressed in Autotypic Tight Junctions of Peripheral Myelinating Schwann Cells [PDF]
Autotypic tight junctions are formed by tight junction-like structures in three regions of myelinating Schwann cells, the paranodal loops, Schmidt–Lanterman incisures, and outer/inner mesaxons, and various tight junction molecules, including claudin-19 and junctional adhesion molecule (JAM)-C.
Shin, Kikuchi +4 more
openaire +2 more sources
Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni [PDF]
Campylobacter jejuni (C. jejuni) is the most common cause of foodborne gastroenteritis worldwide. The bacteria induce diarrhea and inflammation by invading the intestinal epithelium. Curcumin is a natural polyphenol from turmeric rhizome of Curcuma longa,
Bereswill, Stefan +14 more
core +1 more source
Claudins in lung diseases [PDF]
Tight junctions are the most apically localized part of the epithelial junctional complex. They regulate the permeability and polarity of cell layers and create compartments in cell membranes. Claudins are structural molecules of tight junctions.
Ylermi Soini
core +2 more sources
Role of tight junctions in signal transduction: an update [PDF]
Tight junctions (TJs), which are the most apically located of the intercellular junctional complexes, have a barrier function and a fence function. Recent studies show that they also participate in signal transduction mechanisms.
Himi, Tetsuo +3 more
core
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. [PDF]
International audienceABSTRACT: The Blood--brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and ...
Artus, Cédric +4 more
core +4 more sources
Cytokine tuning of intestinal epithelial function [PDF]
The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies.
Andrews, Caroline +2 more
core +4 more sources
Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease [PDF]
Genes that showed greater than four-fold upregulation in IBD.
Alfa Hc Bai +10 more
core +6 more sources
A look at tricellulin and its role in tight junction formation and maintenance
Tight junctions are elaborate networks of transmembrane and cytosolic proteins that regulate epithelial permeability. Tricellulin was the first tight junction protein found at tricellular tight junctions, the specialized structures occurring where three cells meet together. Here, we summarize the current knowledge about tricellulin (marvelD2), a MARVEL
Cibelle, Mariano +3 more
openaire +2 more sources
Impaired growth, immunity, and intestinal barrier in mammals, poultry, and carp have been attributed to the mycotoxin deoxynivalenol (DON). The increased use of plant ingredients in aquaculture feed implies a risk for contamination with mycotoxins.
Torfinn Moldal +4 more
doaj +1 more source
Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer [PDF]
The epithelial-to-mesenchymal transition (EMT) transcriptional program is characterized by repression of E-cadherin (CDH1) and induction of N-cadherin (CDH2), and mesenchymal genes like vimentin (VIM).
Alina Starchenko +32 more
core +2 more sources

