Results 51 to 60 of about 2,596 (169)

Tight junction physiology of pleural mesothelium [PDF]

, 2014
Pleura consists of visceral and parietal cell layers, producing a fluid, which is necessary for lubrication of the pleural space. Function of both mesothelial cell layers is necessary for the regulation of a constant pleural fluid volume and ...
Amasheh, Salah, Markov, Alexander G.
core   +2 more sources

Establishment of a novel probe-based RT-qPCR approach for detection and quantification of tight junctions reveals age-related changes in the gut barriers of broiler chickens.

PLoS ONE, 2021
Tight junctions (TJs) play a dominant role in gut barrier formation, therefore, resolving the structures of TJs in any animal species is crucial but of major importance in fast growing broilers. They are regulated in molecular composition, ultrastructure
J Sophia von Buchholz, Ivana Bilic, Jörg R Aschenbach, Michael Hess, Taniya Mitra, Wageha A Awad   +5 more
doaj   +1 more source

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption [PDF]

, 2020
The epithelial sodium channel (ENaC) can increase the colonic absorptive capacity for salt and water. Campylobacter concisus is a common pathogenic epsilonproteobacterium, causing enteritis and diarrhea. It can induce barrier dysfunction in the intestine,
Bereswill, Stefan, Butkevych, Eduard, Bücker, Roland, Fromm, Anja, Genger, Claudia, Heimesaat, Markus M., Kløve, Sigri, Lee, In-Fah Maria, Lobo de Sá, Fábia Daniela, Mousavi, Soraya, Nagel, Oliver, Nattramilarasu, Praveen Kumar, Nielsen, Hans Linde, Schulzke, Jörg-Dieter, Schweiger, Michal R., Troeger, Hanno   +15 more
core   +2 more sources

Comparison of the performance of raw and Lactobacillus paracasei fermented soybean meal in diets for turbot (Scophthalmus maximus L.): Growth, intestinal morphology, apoptosis, tight junction, and microbiota

Aquaculture Reports, 2022
Fermentation is a promising method to improve the utilization of soybean meal (SM) by fish, and strain is the core of fermentation process. In this study, the effects of Lactobacillus paracasei fermentation on the SM quality were investigated. Also, an 8-
Beili Zhang, Yan Zhang, Meichen Cui, Mengyu Zhang, Jianing Xu, Zhi Zhang, Zhongmin Sui, Lei Wang, Chunyang Zhang, Chaoqun Li, Qinyuan Ma   +10 more
doaj   +1 more source

Protein Kinase C Activation Has Distinct Effects on the Localization, Phosphorylation and Detergent Solubility of the Claudin Protein Family in Tight and Leaky Epithelial Cells [PDF]

, 2010
We have previously shown that protein kinase C (PKC) activation has distinct effects on the structure and barrier properties of cultured epithelial cells (HT29 and MDCK I). Since the claudin family of tight junction (TJ)-associated proteins is considered
Anita Sjö, Karl-Eric Magnusson, Kajsa Holmgren Peterson   +2 more
core   +1 more source

Mechanistic study on Tricellulin regulation of colorectal cancer cell invasion, metastasis and epithelial-mesenchymal transition

结直肠肛门外科
[Objectives] To investigate the related molecular mechanisms by which Tricellulin regulates the invasion, migration and metastasis and epithelial-mesenchymal transition (EMT) progression in colorectal cancer. [Methods] Tissue specimens from 40 colorectal
Yang Wenfang, Liao Cun, Zhang Jinxiu, Cheng Ruoxi, Pan Xiaoping, Chen Qiuling, Tan Yanlin, Feng Kaoyan, Qin Mengbin, Huang Jie’an   +9 more
doaj   +1 more source

Intestinal Barrier Function in Gluten-Related Disorders [PDF]

, 2019
Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite having in common the contact of the gastrointestinal mucosa with components of wheat and other ...
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Schumann, Michael, Withoff, Sebo   +6 more
core   +2 more sources

Tricellulin Expression and its Deletion Effects in the Endolymphatic Sac

The Journal of International Advanced Otology, 2019
Abstract   OBJECTIVES: Tricellulin is a tight junction (TJ)-forming protein that participates in the sealing function of tricellular TJs. Tricellulin-knockout (Tric−/−) mice show progressive hearing loss with degeneration of hair cells in the cochlea without physiological or physical disorders.
Ai, Matsubara, Takenori, Miyashita, Ryuhei, Inamoto, Hirofumi, Sakaguchi, Toru, Kamitani, Nozomu, Mori, Hiroshi, Hoshikawa   +6 more
openaire   +2 more sources

Tricellulin deficiency affects tight junction architecture and cochlear hair cells [PDF]

Journal of Clinical Investigation, 2013
The two compositionally distinct extracellular cochlear fluids, endolymph and perilymph, are separated by tight junctions that outline the scala media and reticular lamina. Mutations in TRIC (also known as MARVELD2), which encodes a tricellular tight junction protein known as tricellulin, lead to nonsyndromic hearing loss (DFNB49).
Gowri, Nayak, Sue I, Lee, Rizwan, Yousaf, Stephanie E, Edelmann, Claire, Trincot, Christina M, Van Itallie, Ghanshyam P, Sinha, Maria, Rafeeq, Sherri M, Jones, Inna A, Belyantseva, James M, Anderson, Andrew, Forge, Gregory I, Frolenkov, Saima, Riazuddin   +13 more
openaire   +2 more sources

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis. [PDF]

, 2018
Patients afflicted with ulcerative colitis (UC) are at increased risk of colorectal cancer. While its causes are not fully understood, UC is associated with defects in colonic epithelial barriers that sustain inflammation of the colon mucosa caused by ...
Alexander, Walker, Dilbarova, Rima, Gilligan, John, Hoxha, Kevther, Kossenkov, Andrew, Mullin, James M., Prendergast, George C., Thomas, Sunil, Whittaker, Kelly   +8 more
core   +2 more sources