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Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

open access: yesTricellulin constitutes a novel barrier at tricellular contacts of epithelial cells
openaire   +1 more source

Tricellulin Effect on Paracellular Water Transport [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
In epithelia, large amounts of water pass by transcellular and paracellular pathways, driven by the osmotic gradient built up by the movement of solutes.
Jörg-Dieter Schülzke   +2 more
exaly   +4 more sources

Apoptotic Fragmentation of Tricellulin [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Apoptotic extrusion of cells from epithelial cell layers is of central importance for epithelial homeostasis. As a prerequisite cell–cell contacts between apoptotic cells and their neighbors have to be dissociated. Tricellular tight junctions (tTJs)
Otmar Huber
exaly   +5 more sources

Tricellulin is a target of the ubiquitin ligase Itch

open access: yesAnnals of the New York Academy of Sciences, 2017
Tricellulin, a member of the tight junction-associated MAGUK protein family, preferentially localizes to tricellular junctions in confluent polarized epithelial cell layers and is downregulated during the epithelial-mesenchymal transition ...
Udo Heinemann   +2 more
exaly   +4 more sources

Tricellulin Is a Tight-Junction Protein Necessary for Hearing [PDF]

open access: yesAmerican Journal of Human Genetics, 2006
The inner ear has fluid-filled compartments of different ionic compositions, including the endolymphatic and perilymphatic spaces of the organ of Corti; the separation from one another by epithelial barriers is required for normal hearing.
Shin-Ichiro Kitajiri   +2 more
exaly   +5 more sources

Tricellulin Expression and its Prognostic Significance in Primary Liver Carcinomas

open access: yesPathology and Oncology Research, 2014
Numerous data suggest that altered expression of tight junction proteins such as occludin and claudins plays important role in carcinogenesis. However, little is known about tricellulin, a transmembrane tight junction protein concentrated where three ...
Zsuzsa Schaff   +2 more
exaly   +5 more sources

High tricellulin expression is associated with better survival in human hepatoblastoma

open access: yesHistopathology, 2014
AIMS The more differentiated fetal component of hepatoblastoma (HB) is characterized by increased expression of tight junction (TJ) proteins claudin-1 and -2 when compared with embryonal component.
Kornélia Baghy   +2 more
exaly   +5 more sources
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Tricellulin forms homomeric and heteromeric tight junctional complexes

Cellular and Molecular Life Sciences, 2010
Sealing of the paracellular cleft by tight junctions is of central importance for epithelia and endothelia to function as efficient barriers between the extracellular space and the inner milieu. Occludin and claudins represent the major tight junction components involved in establishing this barrier function.
Joerg Piontek   +2 more
exaly   +3 more sources

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