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Nuclear localization of tricellulin promotes the oncogenic property of pancreatic cancer
Nuclear localization of tricellulin promotes the oncogenic property of pancreatic canceropenaire
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cellsopenaire +1 more source
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Claudins and tricellulin in fibrolamellar hepatocellular carcinoma
Virchows Archiv, 2011Fibrolamellar hepatocellular carcinoma is a subtype of hepatocellular carcinoma occurring in non-cirrhotic liver at a younger age. The tumor expresses both hepatocellular and cholangiocellular markers. Previously, our group described overexpression of tight junction protein claudin 4 in cholangiocellular carcinoma in contrast to hepatocellular ...
Patonai, Attila +9 more
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Tricellulin forms homomeric and heteromeric tight junctional complexes
Cellular and Molecular Life Sciences, 2010Sealing of the paracellular cleft by tight junctions is of central importance for epithelia and endothelia to function as efficient barriers between the extracellular space and the inner milieu. Occludin and claudins represent the major tight junction components involved in establishing this barrier function.
Julie K, Westphal +8 more
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Tricellulin expression in normal and neoplastic human pancreas
Histopathology, 2012Korompay A, Borka K, Lotz G, Somorácz Á, Törzsök P, Erdélyi‐Belle B, Kenessey I, Baranyai Z, Zsoldos F, Kupcsulik P, Bodoky G, Schaff Z & Kiss A(2012) Histopathology 60, E76–E86Tricellulin expression in normal and neoplastic human pancreasAims: Tricellulin is a member of the family of tight junction proteins, which are found concentrated mainly at
Korompay, Anna +12 more
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Tricellulin expression in brain endothelial and neural cells
Cell and Tissue Research, 2012Tricellulin is a tight junction (TJ) protein, which is not only concentrated at tricellular contacts but also present at bicellular contacts between epithelial tissues. We scrutinized the brain for tricellulin expression in endothelial and neural cells by using real-time polymerase chain reaction, Western blot and immunohistochemical and ...
Cibelle, Mariano +11 more
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Evidence of tricellulin expression by immune cells, particularly microglia
Biochemical and Biophysical Research Communications, 2011Tight junctions (TJs) are elaborate structures located on the apical region of epithelial cells that limit paracellular permeability. Tricellulin is a recently discovered TJ protein, which is concentrated at the structurally specialized tricellular TJs but also present at bicellular contacts between epithelial cells, namely in the stomach ...
Cibelle, Mariano +5 more
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Trictide, a tricellulin‐derived peptide to overcome cellular barriers
Annals of the New York Academy of Sciences, 2017AbstractThe majority of tight junction (TJ) proteins restrict the paracellular permeation of solutes via their extracellular loops (ECLs). Tricellulin tightens tricellular TJs (tTJs) and regulates bicellular TJ (bTJ) proteins. We demonstrate that the addition of recombinantly produced extracellular loop 2 (ECL2) of tricellulin opens cellular barriers ...
Jimmi, Cording +10 more
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Differential Phosphorylation of Occludin and Tricellulin by CK2 and CK1
Annals of the New York Academy of Sciences, 2009In epithelial and endothelial cell layers tight junctions form selective apicolateral paracellular barriers separating luminal and extracellular spaces from the underlying tissues. Within the tight junctions the tetraspan transmembrane proteins occludin, claudins, and tricellulin form anastomosing strands of protein complexes, which interconnect ...
Max J, Dörfel +2 more
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Tricellulin Modulates Transport of Macromolecules in the Salivary Gland
Journal of Dental Research, 2019Volume and composition of saliva are crucial for oral and systemic health. How substances, particularly macromolecules, are transported across the salivary gland epithelium has not been established in detail. Tricellulin is a component of tricellular tight junctions that form a central tube to serve as an important route for macromolecule transport ...
S.N. Min +6 more
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