Results 51 to 60 of about 13,719 (224)

Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues [PDF]

, 2014
Hapten heterology was introduced into the steps of hybridoma selection for the development of monoclonal antibodies (MAbs) against deoxynivalenol (DON).
Bracke, Marc, De Saeger, Sarah, Deforce, Dieter, Eremin, S, Galvita, Anastasia, Guo, Yirong, Heyerick, Arne, Sanders, Melanie   +7 more
core   +1 more source

Phylogenetic Variation of Tri1 Gene and Development of PCR–RFLP Analysis for the Identification of NX Genotypes in Fusarium graminearum Species Complex

Toxins, 2023
NX toxins have been described as a novel group of type A trichothecenes produced by members of the Fusarium graminearum species complex (FGSC). Differences in structure between NX toxins and the common type B trichothecenes arise from functional ...
Meiling Gao, Mengyuan Zhang, Jiahui Zhang, Xianli Yang, Mohamed F. Abdallah, Jianhua Wang   +5 more
doaj   +1 more source

Examining the transcriptional response in wheat Fhb1 near-isogenic lines to Fusarium graminearum infection and deoxynivalenol treatment [PDF]

, 2016
Citation: Hofstad, A. N., Nussbaumer, T., Akhunov, E., Shin, S., Kugler, K. G., Kistler, H. C., . . . Muehlbauer, G. J. (2016). Examining the transcriptional response in wheat Fhb1 near-isogenic lines to Fusarium graminearum infection and deoxynivalenol ...
Anna N. Hofstad, Desjardins A.E., Eduard Akhunov, Gary J. Muehlbauer, H. Corby Kistler, Karl G. Kugler, Klaus F.X. Mayer, Leonard K.J., R Development Core Team, Sanghyun Shin, The European Commission, Thomas Nussbaumer   +11 more
core   +2 more sources

Pro-Inflammatory Effects of NX-3 Toxin Are Comparable to Deoxynivalenol and not Modulated by the Co-Occurring Pro-Oxidant Aurofusarin

Microorganisms, 2020
The type A trichothecene NX-3, produced by certain Fusarium graminearum strains, is similar to the mycotoxin deoxynivalenol (DON), with the exception that it lacks the carbonyl moiety at the C-8 position.
Lydia Woelflingseder, Nadia Gruber, Gerhard Adam, Doris Marko   +3 more
doaj   +1 more source

Mycotoxins‐contaminated wheat matrices bioconversion by Tenebrio molitor larvae (Coleoptera: Tenebrionidae)

Insect Science, EarlyView.
Larval development time, ADG, survival rate and substrate consumption were not negatively affected by the levels of mycotoxins contamination Larvae excreted most of the ingested DON and its derivatives through exuviae and frass The mycotoxin accumulation rates observed in larvae were always below the current legal limits for livestock feed Abstract ...
Valentina Candian, Valentina Scarpino, Alessandro Bona, Rosemarie Tedeschi, Massimo Blandino   +4 more
wiley   +1 more source

Can Wapiti (Cervus elaphus) Browsing Stimulate the Chemical Defense of Taxus cuspidata—A Case of Northeast China Tiger and Leopard National Park

Integrative Zoology, EarlyView.
We study that browsing by wapiti reduces the growth of saplings, and it develop chemical defenses to prevent themselves browsed again. These results reduce our concern about wapiti browse T. cuspidate saplings, and provide basic data for the study of the interaction between them, and also provide theoretical basis for the population restoration and ...
Jianan Feng, Hairong Du, Xianzhe Wang, Minghai Zhang   +3 more
wiley   +1 more source

Comparative Analysis of Deoxynivalenol Biosynthesis Related Gene Expression among Different Chemotypes of Fusarium graminearum in Spring Wheat [PDF]

, 2016
Fusarium mycotoxins, deoxynivalenol (DON) and nivalenol (NIV) act as virulence factors and are essential for symptom development after initial infection in wheat. To date, 16 genes have been identified in the deoxynivalenol biosynthesis pathway. However,
Chami C. Amarasinghe, W. G. Dilantha Fernando   +1 more
core   +3 more sources

Coniferyl aldehyde from the phenylpropanoid pathway targets pyruvate kinase in Dactylobotrys graminicola to confer sheath rot resistance in hulless barley

Journal of Integrative Plant Biology, EarlyView.
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng, Liyifan Chen, Jianguo Wei, Yuandi Xu, Rangrang Chen, Yu Li, Yan Liu, Jiahui Yan, Lu Hou, Yiliang Chen, Zhensheng Kang, Haifeng Zhang, Qiang Yao   +12 more
wiley   +1 more source

Reduced Toxicity of Trichothecenes, Isotrichodermol, and Deoxynivalenol, by Transgenic Expression of the Tri101 3-O-Acetyltransferase Gene in Cultured Mammalian FM3A Cells

Toxins, 2019
In trichothecene-producing fusaria, isotrichodermol (ITDol) is the first intermediate with a trichothecene skeleton. In the biosynthetic pathway of trichothecene, a 3-O-acetyltransferase, encoded by Tri101, acetylates ITDol to a less-toxic intermediate ...
Nozomu Tanaka, Ryo Takushima, Akira Tanaka, Ayaki Okada, Kosuke Matsui, Kazuyuki Maeda, Shunichi Aikawa, Makoto Kimura, Naoko Takahashi-Ando   +8 more
doaj   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source