Results 111 to 120 of about 22,737 (222)
Allergen Protease Act d 1 Induces TLR4‐Dependent Inflammation via Ectodomain Cleavage
Allergy, EarlyView.
Milena Zlatanova +2 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
ON A GENERALIZED TRIF'S MAPPING IN BANACH MODULES OVER A C*-ALGEBRA
Journal of the Korean Mathematical Society, 2006 The authors deal with the functional equation \[ \begin{multlined} mn X_{mn-2}C_{k-2} f\left(\frac{x_1+\cdots+x_{mn}}{mn}\right) +mX_{mn-2}C_{k-1}\sum_{i=1}^{n} f\left(\frac{x_{mi-m+1}+\cdots+x_{mi}}{m}\right)\\ =k\sum_{1\leq ...
Park, Chun-Gil, Rassias, Themistocles M.
openaire +3 more sources
Effects of TLR3 and TRIF siRNA on chemokine mRNA expression.
, 2015 BEAS-2B cells were transfected with three siRNAs targeting TLR3 (#1–#3). After 72 h, qRT-PCR (A) and Western blot (B) were used to evaluate the knockdown efficacy of each siRNA. All siRNAs for TLR3 abolished TLR3 mRNA expression and protein production in
Masafumi Horie (379262) +11 more
core +1 more source
Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1956-1971, October 2026.ABSTRACT Aims Purpose: Dictionary matching is a standard tool in quantitative MRI (qMRI), but typically lacks uncertainty quantification (UQ). This is critical when advanced reconstructions (e.g., compressed sensing, deep learning) introduce complex‐valued, spatially varying, and temporally correlated noise that violates standard assumptions of ...
Brian Toner +7 more
wiley +1 more source
Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility.
PLoS Pathogens, 2012 Rotavirus is a major cause of diarrhea worldwide and exhibits a pronounced small intestinal epithelial cell (IEC) tropism. Both human infants and neonatal mice are highly susceptible, whereas adult individuals remain asymptomatic and shed only low ...
Johanna Pott +10 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways.
PLoS ONE, 2018 Toll-like receptors (TLRs) recognize the conserved molecular patterns in microorganisms and trigger myeloid differentiation primary response 88 (MyD88) and/or TIR-domain-containing adapter-inducing interferon-β (TRIF) pathways that are critical for host ...
Zheng Pang +6 more
doaj +1 more source
Advanced Science, Volume 13, Issue 50, 7 September 2026.This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu +6 more
wiley +1 more source
RING/B-box of TRIM38 is critical for TRIF degradation.
, 2012 (A) TRIM38 catalyzes K48-linked ubiquitination of TRIF. 293T cells were transfected with plasmids expressing Myc-tagged full-length or RING/B-box domain deleted (ΔRING/B-box) TRIM38, Flag-TRIF, and HA-ubiquitin plasmids.
Xinlei Liu (128686) +6 more
core +1 more source