Results 81 to 90 of about 499 (147)

Reactivation of organophosphate-inhibited serum butyrylcholinesterase by novel substituted phenoxyalkyl pyridinium oximes and traditional oximes. [PDF]

Toxicology, 2021
Nichols RH, Chambers JE.
europepmc   +1 more source

A-series agent A-234: initial in vitro and in vivo characterization. [PDF]

Arch Toxicol
Hrabinova M, Pejchal J, Hepnarova V, Muckova L, Junova L, Opravil J, Zdarova Karasova J, Rozsypal T, Dlabkova A, Rehulkova H, Kucera T, Vecera Z, Caisberger F, Schmidt M, Soukup O, Jun D.   +15 more
europepmc   +1 more source

Structure-activity studies of bispyridinium antinicotinics to select candidates to treat soman intoxication as part of a combined therapy. [PDF]

PLoS One
Turner SR, Timperley CM, Bird M, Green AC, Price ME, Rice H, Chad JE, Tattersall JEH.   +7 more
europepmc   +1 more source

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase. [PDF]

BMC Pharmacol Toxicol, 2018
Kuca K, Musilek K, Jun D, Zdarova-Karasova J, Nepovimova E, Soukup O, Hrabinova M, Mikler J, Franca TCC, Da Cunha EFF, De Castro AA, Valis M, Ramalho TC.   +12 more
europepmc   +1 more source

Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates. [PDF]

Ann N Y Acad Sci, 2020
Chambers JE, Meek EC.
europepmc   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators. [PDF]

J Enzyme Inhib Med Chem, 2021
Kitagawa DAS, Rodrigues RB, Silva TN, Dos Santos WV, da Rocha VCV, de Almeida JSFD, Bernardo LB, Carvalho-Silva T, Ferreira CN, da Silva AAT, Simas ABC, Nepovimova E, Kuča K, França TCC, Cavalcante SFA.   +14 more
europepmc   +1 more source

Dose-Dependent Tissue Distribution of K117, a Bis-pyridinium Aldoxime, in Rats [PDF]

, 2019
Barbara Malawska, Chen Z., Ernest A. Adeghate, Gellért Karvaly, Horn G., Huba Kalász, Judit Szepesy, Juhn S.K., Jun D., Jung Young-Sik, Kalász H., Kalász H., Kamil Kuca, Kamil Musilek, Karasova J.Z., Kornélia Tekes, Kovarik Z., Kuca K., Lockridge O., Lorke D.E., Masson P., Nachon F., Okuno S., Sakurada K., Strelitz J., Sun W., Syed M. Nurulain, Tibor Zelles, Tran Ba Huy P.   +28 more
core   +1 more source

Antidotes in Clinical Toxicology-Critical Review. [PDF]

Toxics, 2023
Kobylarz D, Noga M, Frydrych A, Milan J, Morawiec A, Glaca A, Kucab E, Jastrzębska J, Jabłońska K, Łuc K, Zdeb G, Pasierb J, Toporowska-Kaźmierak J, Półchłopek S, Słoma P, Adamik M, Banasik M, Bartoszek M, Adamczyk A, Rędziniak P, Frączkiewicz P, Orczyk M, Orzechowska M, Tajchman P, Dziuba K, Pelczar R, Zima S, Nyankovska Y, Sowińska M, Pempuś W, Kubacka M, Popielska J, Brzezicki P, Jurowski K.   +33 more
europepmc   +1 more source

Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice. [PDF]

Molecules, 2022
Wei Z, Zhang X, Nie H, Yao L, Liu Y, Zheng Z, Ouyang Q.   +6 more
europepmc   +1 more source

Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes. [PDF]

Environ Toxicol Pharmacol, 2019
Bharate SB, Chao CK, Thompson CM.
europepmc   +1 more source