Results 61 to 70 of about 177 (110)

Acetylcholinesterase Inhibitors and Drugs Acting on Muscarinic Receptors- Potential Crosstalk of Cholinergic Mechanisms During Pharmacological Treatment. [PDF]

Curr Neuropharmacol, 2017
Soukup O, Winder M, Killi UK, Wsol V, Jun D, Kuca K, Tobin G.   +6 more
europepmc   +1 more source

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging. [PDF]

Arch Toxicol
Čadež T, Maček Hrvat N, Šinko G, Kalisiak J, Radić Z, Fokin VV, Sharpless KB, Taylor P, Kovarik Z.   +8 more
europepmc   +1 more source

The present approaches to the development of prophylactic and therapeutic antidotes against nerve agents. [PDF]

Interdiscip Toxicol, 2008
Kassa J, Bajgar J, Kuča K, Musílek K, Karasová J.   +4 more
europepmc   +1 more source

Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. [PDF]

Bioorg Med Chem, 2010
Bharate SB, Guo L, Reeves TE, Cerasoli DM, Thompson CM.   +4 more
europepmc   +1 more source

Antimicrobial, antimalarial, and antileishmanial activities of mono- and bis-quaternary pyridinium compounds. [PDF]

Chem Biol Drug Des, 2010
Bharate SB, Thompson CM.
europepmc   +1 more source

A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication. [PDF]

Toxicol Res (Camb), 2016
Nepovimova E, Korabecny J, Dolezal R, Nguyen TD, Jun D, Soukup O, Pasdiorova M, Jost P, Muckova L, Malinak D, Gorecki L, Musilek K, Kuca K.   +12 more
europepmc   +1 more source

Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) study. [PDF]

Int J Mol Sci, 2013
Sepsova V, Karasova JZ, Korabecny J, Dolezal R, Zemek F, Bennion BJ, Kuca K.   +6 more
europepmc   +1 more source

Tegavivint triggers TECR-dependent nonapoptotic cancer cell death. [PDF]

Nat Chem Biol
Leak L, Wang Z, Joseph AJ, Johnson B, Chan AA, Decosto CM, Magtanong L, Ko PJ, Lee WC, Ritho J, Manukian S, Millner A, Chitkara S, Salinas JJ, Skouta R, Rees MG, Ronan MM, Roth JA, Myers CL, Moffat J, Boone C, Bensinger SJ, Nathanson DA, Atilla-Gokcumen GE, Moding EJ, Dixon SJ.   +25 more
europepmc   +1 more source

Towards Completion of the "Periodic Table" of Di-2-Pyridyl Ketoxime. [PDF]

Molecules
Stamou C, Polyzou CD, Lada ZG, Konidaris KF, Perlepes SP.   +4 more
europepmc   +1 more source

Efficacy of Trimedoxime in Mice Poisoned With Dichlorvos, Heptenophos or Monocrotophos [PDF]

Basic and Clinical Pharmacology and Toxicology, 2005
Abstract: The aim of the study was to examine antidotal potency of trimedoxime in mice poisoned with three direct dimethoxy‐substituted organophosphorus inhibitors. In order to assess the protective efficacy of trimedoxime against dichlorvos, heptenophos or monocrotophos, median effective doses and efficacy half‐times were calculated.
Miloš P Stojiljković, Biljana Antonijević, Dubravko R Bokonjić   +2 more
exaly   +9 more sources