Results 21 to 30 of about 18,891 (189)
Microbiome, trimethylamine N-oxide, and cardiometabolic disease [PDF]
Translational Research, 2017 There is increasing appreciation that changes in microbiome composition and function can promote long-term susceptibility for cardiometabolic risk. Gut microbe-derived metabolites that are biologically active, such as trimethylamine N-oxide (TMAO), are now recognized as contributors to atherogenesis.
W.H. Wilson Tang, Stanley L. Hazen
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Influence of Trimethylamine N-Oxide on Platelet Activation
Nutrients, 2022 Microbiome-derived trimethylamine N-oxide (TMAO) has been associated with platelet hyperreactivity and subsequent atherogenesis. Whether physiological TMAO-levels influence platelet-derived lipid mediators remains unknown. Little is known about pre-analytic factors potentially influencing TMAO concentrations. We aimed at developing a quantitative LC-MS/
Emonds, Julian Josef +7 more
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Trimethylamine N-oxide and kidney diseases: what do we know?
Brazilian Journal of Nephrology, 2023 In the human gut, there is a metabolically active microbiome whose metabolic products reach various organs and are used in the physiological activities of the body.
Ozkan Gungor +2 more
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Trimethylamine-N-Oxide and Heart Failure
Journal of the American College of Cardiology, 2015 The new study by Tang et al. [(1)][1] demonstrating an inverse correlation of serum levels of trimethylamine- N -oxide (TMAO) with survival in patients with heart failure (HF) is intriguing and thought provoking. Similar findings have been published recently by Norwegian researchers.
McCarty, Mark F. +1 more
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Intestinal Microbiota Metabolism and Atherosclerosis
Chinese Medical Journal, 2015 Objective: This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target.
Tian-Xing Liu +2 more
doaj +1 more source
TMAO metaorganismal pathway and chronic inflammatory diseases [PDF]
Exploration of MedicineNutrients containing a trimethylamine (TMA) moiety in their structure can be metabolized by the gut microbiota through enzymatic cleavage of the C-N bond, producing TMA.
Zeneng Wang, Shumei Man, Robert Koeth
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Quantification of Trimethylamine-N-Oxide and Trimethylamine in Fish Oils for Human Consumption
MoleculesSupplementing fish oil is one of the strategies to reduce the risk of cardiovascular disease, the leading cause of death around the world. Contradictorily, fish oil may also contain trimethylamine-N-oxide, a recently emerged risk factor for ...
Dominik Dörfel +2 more
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Analysis of metabolomic patterns in thoroughbreds before and after exercise [PDF]
Asian-Australasian Journal of Animal Sciences, 2017 Objective Evaluation of exercise effects in racehorses is important in horseracing industry and animal health care. In this study, we compared metabolic patterns between before and after exercise to screen metabolic biomarkers for exercise effects in ...
Hyun-Jun Jang +8 more
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Transient trimethylaminuria related to menstruation
BMC Medical Genetics, 2007 Background Trimethylaminuria, or fish odor syndrome, includes a transient or mild malodor caused by an excessive amount of malodorous trimethylamine as a result of body secretions.
Yamazaki Hiroshi +2 more
doaj +1 more source
mSystems, 2021 The gut microbiota-dependent metabolite trimethylamine-N-oxide (TMAO) is linked to an increased risk for cardiovascular diseases. Trimethylamine (TMA), which is subsequently oxidized to TMAO in the liver, is formed by intestinal bacteria via distinct ...
Silke Rath +11 more
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