Quantification of Trimethylamine-N-Oxide and Trimethylamine in Fish Oils for Human Consumption
Supplementing fish oil is one of the strategies to reduce the risk of cardiovascular disease, the leading cause of death around the world. Contradictorily, fish oil may also contain trimethylamine-N-oxide, a recently emerged risk factor for ...
Sascha Rohn +2 more
core +2 more sources
Loop Diuretics Inhibit Renal Excretion of Trimethylamine N-Oxide. [PDF]
This study demonstrates, for the first time, that renal tubular excretion of trimethylamine N-oxide (TMAO) is inhibited by concomitant loop diuretic administration.
Wang, Zeneng +7 more
core +1 more source
Recent Advance for PVDF Based Flexible Piezoelectric Sensors
This review focus on the structural regulation of PVDF via boundary confinement, blending regulation, electric‐field‐assisted orientation, and chemical modification for flexible piezoelectric sensors. ABSTRACT The rapid advancement of flexible electronics, wearable devices, and biomedical engineering has spurred increasing demand for sensor materials ...
Chaoran Tan +4 more
wiley +1 more source
Pressing the trimethylamine N-oxide narrative
We read with interest the correspondence titled “Gut Microbe-Generated Trimethylamine N-Oxide from Dietary Choline is Prothrombotic in Subjects”, published by Zhu et al . in the journal Circulation (1). This work builds on an emerging body of evidence which has suggested a role for the gut-derived metabolite, trimethylamine N -oxide (TMAO), in the ...
Kevin C. Klatt, Marie A. Caudill
openaire +1 more source
Controlling the kinetics of interaction between microtubules and kinesins over a wide temperature range using the deep-sea osmolyte trimethylamine N-oxide [PDF]
Trimethylamine N-oxide is found to be effective in regulating the interaction between microtubules and kinesins over a wide temperature range. The lifetime of the motility of microtubules on kinesins at high temperatures is prolonged using trimethylamine
Kabir, Arif Md Rashedul +4 more
core +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Gut Microbial Signatures of Distinct Trimethylamine N-Oxide Response to Raspberry Consumption [PDF]
Maximilien Franck +9 more
openalex +1 more source
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
From Phosphinimines to Four‐Membered SiCPN Cations: Insights Into N–Si Bonding and Ring Strain
Sterically tuned N‐silyl phosphinimines enable four‐membered SiCPN cations. Hydride abstraction yields cyclic cations for Me and iPr substituents at silicon, while tBu gives a protonated intermediate. Multinuclear NMR spectroscopy, X‐ray crystallography, thermochemical density functional theory investigations, and natural bond orbital analyses reveal ...
Alexander Falk, Jonathan O. Bauer
wiley +1 more source
Tracking the Reaction of Organoazides with Linear Chromium Silylamides
The multifaceted outcome of the interaction of linear chromium silylamides with organoazides is presented. It leads to terminal and bridging imido complexes, as well as azide adducts. With acylazide, a terminal chromium oxide is obtained. The reaction of organoazides with a linear chromium(I) silylamide leads to the observation of rare monomeric and ...
Andres Gonzalez +5 more
wiley +1 more source

