Relationship between red meat metabolite trimethylamine N-oxide and cardiovascular disease
Heart and Mind, 2022 Many cardiovascular diseases (CVD) are caused by the interplay of lifestyle and genetic factors. Studies have suggested an association between red meat consumption and increased CVD risk. There is evidence indicating that trimethylamine N-oxide (TMAO), a
Angatu Yousuf, David G McVey, Shu Ye
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Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
Cellular Physiology and Biochemistry, 2017 Background/Aim: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial metabolism of dietary phosphatidylcholine has been recently associated with atherosclerosis and increased risk of cardiovascular diseases (CVD) in rodents and humans.
Krishna M. Boini +3 more
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Trimethylamine N-Oxide Promotes Cell Proliferation and Angiogenesis in Colorectal Cancer
Journal of Immunology Research, 2022 Background. Of all intestinal microbiome-derived metabolites, trimethylamine N-oxide (TMAO) has received increasing attention because of its potent role in colorectal cancer development.
Shuyan Yang +5 more
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Electronic fluctuation in physiological solutions: Trimethylamine N-oxide and tert-butyl alcohol [PDF]
, 2022 Nahoko Kuroki +3 more
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Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension
Redox Biology, 2021 Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the pathogenesis of chronic kidney disease (CKD), diabetes, obesity and atherosclerosis.
Shan Jiang +19 more
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Gut Microbial Signatures of Distinct Trimethylamine N-Oxide Response to Raspberry Consumption [PDF]
, 2022 Maximilien Franck +9 more
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Association between plasma trimethylamine N-oxide level and atrial fibrillation [PDF]
Jichu yixue yu linchuangObjective To explore the relationship between plasma trimethylamine N-oxide(TMAO) level and atrial fibrillation(AF) by a clinical trial. Methods Totally 257 patients with AF were enrolled including 114 patients with paroxysmal AF and 143 with ...
YANG Wentao, ZHAO Qing, LI Xiangdong, WANG Yutang, LIU Wei
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Targeting Trimethylamine N-Oxide: A New Therapeutic Strategy for Alleviating Atherosclerosis
Frontiers in Cardiovascular Medicine, 2022 Atherosclerosis (AS) is one of the most common cardiovascular diseases (CVDs), and there is currently no effective drug to reverse its pathogenesis. Trimethylamine N-oxide (TMAO) is a metabolite of the gut flora with the potential to act as a new risk ...
Lele Jing +6 more
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Clinical Interventions in Aging, 2021 Rui Huang,1,* Li Yan,2,* Yuhua Lei1 1Cardiovascular Disease Center, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, Enshi Prefecture, 445000, Hubei Province, People’s Republic of China ...
Huang R, Yan L, Lei Y
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Trimethylamine N-Oxide: The Good, the Bad and the Unknown
Toxins, 2016 Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein ...
Manuel T. Velasquez +3 more
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