Results 61 to 70 of about 18,891 (189)

Fasting and postprandial trimethylamine N ‐oxide in sedentary and endurance‐trained males following a short‐term high‐fat diet [PDF]

, 2021
Cortney Steele, Mary Elizabeth Baugh, Laura E. Griffin, Andrew P. Neilson, Brenda M. Davy, Matthew W. Hulver, Kevin P. Davy   +6 more
openalex   +1 more source

Water-mediated interactions between trimethylamine-N-oxide and urea

Physical Chemistry Chemical Physics, 2015
The osmoprotectant trimethylamine-N-oxide (TMAO) interacts with the protein denaturant ureaviathe hydrogen-bonded water network.
Hunger, J., Ottosson, N., Mazur, K., Bonn, M., Bakker, H.   +4 more
openaire   +4 more sources

Trimethylamine N-oxide impairs β-cell function and glucose tolerance

Nature Communications
β-Cell dysfunction and β-cell loss are hallmarks of type 2 diabetes (T2D). Here, we found that trimethylamine N-oxide (TMAO) at a similar concentration to that found in diabetes could directly decrease glucose-stimulated insulin secretion (GSIS) in MIN6 ...
Lijuan Kong, Qijin Zhao, Xiaojing Jiang, Jinping Hu, Qian Jiang, Li Sheng, Xiaohong Peng, Shusen Wang, Yibing Chen, Yanjun Wan, Shaocong Hou, Xingfeng Liu, Chunxiao Ma, Yan Li, Li Quan, Liangyi Chen, Bing Cui, Pingping Li   +17 more
doaj   +1 more source

Monooxygenase-dehydrogenase cascade for sustained enzymatic remediation of TMA in salmon protein hydrolysates

Applied and Environmental Microbiology
Fish protein hydrolysates hold great promise as nutraceuticals, yet their application as food ingredients or nutraceuticals is currently limited by their fish-like odor. This odor is mainly due to the presence of trimethylamine (TMA), a volatile biogenic
Rasmus Ree, Øivind Larsen, Sushil Gaykawad, Sreerekha S. Ramanand, Antonio García-Moyano, Irina Elena Chiriac, Pål Puntervoll, Gro Elin Kjæreng Bjerga   +7 more
doaj   +1 more source

Association between risk of preeclampsia and maternal plasma trimethylamine-N-oxide in second trimester and at the time of delivery [PDF]

, 2020
Xin Huang, Zuodong Li, Zhou Gao, Dapeng Wang, Xiaohui Li, Ying Li, Chunmei Mi, Jun Lei   +7 more
openalex   +1 more source

Phenotypic high-throughput screening identifies modulators of gut microbial choline metabolism

mBio
Anaerobic metabolism of dietary choline to trimethylamine (TMA) by the human gut microbiome is a disease-associated pathway. The host’s impaired ability to oxidize TMA to trimethylamine-N-oxide (TMAO) results in trimethylaminuria (TMAU), while elevated ...
Amelia Y. M. Woo, Walter J. Sandoval-Espinola, Maud Bollenbach, Alison Wong, Mariko Sakanaka-Yokoyama, Qijun Zhang, Vincent Nieto, Federico E. Rey, Emily P. Balskus   +8 more
doaj   +1 more source

The Association between Trimethylamine N-Oxide and Its Predecessors Choline, L-Carnitine, and Betaine with Coronary Artery Disease and Artery Stenosis [PDF]

, 2020
Fei Guo, Jun Zhou, Zhenyu Li, Zaixin Yu, Dongsheng Ouyang   +4 more
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Effect of urea and tmao on lipid bilayers

European Pharmaceutical Journal, 2017
We study the effect of the osmolytes, Urea and trimethylamine-N-oxide (TMAO) on POPE (1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine) lipid membranes using SAXS/WAXS and DSC.
Valerio J., Bernstorff S., Funari S.S.
doaj   +1 more source

Trimethylamine N -Oxide

Recent evidence, including massive gene-expression analysis and a wide-variety of other multi-omics approaches, demonstrates an interplay between gut microbiota and the regulation of plasma lipids. Gut microbial metabolism of choline and -carnitine results in the formation of trimethylamine (TMA) and concomitant conversion into trimethylamine- N -oxide
Canyelles, Marina||, Tondo, Mireia||, Cedó, Lídia||, Farràs Mañé, Marta||, Escolà-Gil, Joan Carles||, Blanco Vaca, Francisco||   +5 more
openaire   +1 more source

Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide Contributes to Cardiac Dysfunction in Western Diet-Induced Obese Mice [PDF]

, 2017
Kui Chen, Xiaoqian Zheng, Mingchen Feng, Dongliang Li, Hongqi Zhang   +4 more
openalex   +1 more source