Results 11 to 20 of about 11,599 (170)

Trimethylamine N-Oxide (TMAO) and Trimethylamine (TMA) Determinations of Two Hadal Amphipods

Journal of Marine Science and Engineering, 2022
Hadal trenches are a unique habitat with high hydrostatic pressure, low temperature and scarce food supplies. Amphipods are the dominant scavenging metazoan species in this ecosystem.
Qi Liu, Shouwen Jiang, Wenhao Li, Binbin Pan, Qianghua Xu   +4 more
doaj   +2 more sources

Trimethylamine N-oxide (TMAO) in human health. [PDF]

EXCLI J, 2021
Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and diseases, this topic is very popular and is often taken up by researchers. TMAO is a low molecular weight compound that belongs to the class of amine oxides. It is formed by the process of oxidation of trimethylamine (TMA) by the hepatic flavin monooxygenases (FMO1 ...
Gatarek P, Kaluzna-Czaplinska J.
europepmc   +3 more sources

Contribution of Trimethylamine N-Oxide (TMAO) to Chronic Inflammatory and Degenerative Diseases. [PDF]

Biomedicines, 2023
Trimethylamine N-oxide (TMAO) is a metabolite produced by the gut microbiota and has been mainly associated with an increased incidence of cardiovascular diseases (CVDs) in humans. There are factors that affect one’s TMAO level, such as diet, drugs, age, and hormones, among others.
Constantino-Jonapa LA, Espinoza-Palacios Y, Escalona-Montaño AR, Hernández-Ruiz P, Amezcua-Guerra LM, Amedei A, Aguirre-García MM.   +6 more
europepmc   +4 more sources

Association of the Chronotype Score with Circulating Trimethylamine N-Oxide (TMAO) Concentrations. [PDF]

Nutrients, 2021
Individual differences in the chronotype, an attitude that best expresses the individual circadian preference in behavioral and biological rhythms, have been associated with cardiometabolic risk and gut dysbiosis. Up to now, there are no studies evaluating the association between chronotypes and circulating TMAO concentrations, a predictor of ...
Barrea L, Muscogiuri G, Pugliese G, Graziadio C, Maisto M, Pivari F, Falco A, Tenore GC, Colao A, Savastano S.   +9 more
europepmc   +5 more sources

Trimethylamine N-oxide (TMAO) in patients with subarachnoid hemorrhage: a prospective observational study. [PDF]

Acta Neurochir (Wien), 2023
Abstract Background It is suspected that microbiome-derived trimethylamine N-oxide (TMAO) may enhance platelet responsiveness and accordingly be thrombophilic. The purpose of this prospective observational study is to evaluate TMAO in patients with subarachnoid hemorrhage (SAH) and compare it with a control group.
Emonds JJ, Arlt F, Gaudl A, Reinicke M, Heinemann M, Lindner D, Laudi S, Ceglarek U, Meixensberger J.   +8 more
europepmc   +3 more sources

Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia. [PDF]

Alzheimers Res Ther
AbstractBackgroundThe gut-derived metabolite Trimethylamine N-oxide (TMAO) and its precursors - betaine, carnitine, choline, and deoxycarnitine – have been associated with an increased risk of cardiovascular disease, but their relation to cognition, neuroimaging markers, and dementia remains uncertain.MethodsIn the population-based Rotterdam Study, we ...
Yaqub A, Vojinovic D, Vernooij MW, Slagboom PE, Ghanbari M, Beekman M, van der Grond J, Hankemeier T, van Duijn CM, Ikram MA, Ahmad S.   +10 more
europepmc   +6 more sources

Impact of trimethylamine N-oxide (TMAO) metaorganismal pathway on cardiovascular disease. [PDF]

J Lab Precis Med, 2020
Host-microbes interaction plays a crucial role in cardiovascular disease (CVD) pathogenesis, mechanistically via metaorganismal pathways. The trimethylamine N-oxide (TMAO) metaorganismal pathway is the most deeply investigated one, which comprises trimethylamine precursors, such as choline, trimethylamine lyase, trimethylamine, host liver FMO3, TMAO ...
Zhao Y, Wang Z.
europepmc   +3 more sources

Computational Study of Selected Amine and Lactam N-Oxides Including Comparisons of N-O Bond Dissociation Enthalpies with Those of Pyridine N-Oxides

Molecules, 2020
A computational study of the structures and energetics of amine N-oxides, including pyridine N-oxides, trimethylamine N-oxide, bridgehead bicyclic amine N-oxides, and lactam N-oxides, allowed comparisons with published experimental data.
Arthur Greenberg, Alexa R. Green, Joel F. Liebman   +2 more
doaj   +1 more source

Effects of Urea and Trimethylamine-N-Oxide (TMAO) on the Interactions of Lysozyme in Solution [PDF]

Biophysical Journal, 2005
The effect of two physiological cosolutes (urea and trimethylamine-N-oxide) and of KCl on the intermolecular interactions in concentrated lysozyme solutions were studied by synchrotron radiation small angle x-ray scattering. The evolution of the structure factors as a function of cosolute and/or salt concentration was modeled using pair potentials ...
Niebuhr, Marc, Koch, Michel H.J.
openaire   +2 more sources

No effect of plasma trimethylamine N-Oxide (TMAO) and plasma trimethyllysine (TML) on the association between choline intake and acute myocardial infarction risk in patients with stable angina pectoris

Human Nutrition & Metabolism, 2020
Plasma concentrations of trimethylamine N-oxide (TMAO) have been linked to cardiovascular disease (CVD) risk and mortality. TMAO is formed through the bacterial conversion of trimethylamine which is obtained either directly from food, generated from ...
Anthea Van Parys, Vegard Lysne, Jannike Øyen, Jutta Dierkes, Ottar Nygård   +4 more
doaj   +1 more source