Results 111 to 120 of about 35,994 (298)
The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII
Journal of Experimental & Clinical Cancer Research, 2018 Oncogenes derived from the neurotrophin receptor tropomyosin-related kinase TrkA act as drivers in sub-populations of a wide-range of human cancers. This, combined with a recent report that both adult and childhood cancers driven by novel oncogenic TrkA ...
Antonietta Rosella Farina +6 more
doaj +1 more source
p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. [PDF]
, 2013 The p75 neurotrophin receptor (p75(NTR)) is a member of the tumor necrosis factor receptor superfamily with a widespread pattern of expression in tissues such as the brain, liver, lung, and muscle.
Akassoglou, Katerina +7 more
core +2 more sources
Elp1 function in placode‐derived neurons is critical for proper trigeminal ganglion development
Developmental Dynamics, Volume 254, Issue 6, Page 494-512, June 2025.Abstract Background The trigeminal nerve is the largest cranial nerve and functions in somatosensation. Cell bodies of this nerve are positioned in the trigeminal ganglion, which arises from the coalescence of neural crest and placode cells. While this dual cellular origin has been known for decades, the molecular mechanisms controlling trigeminal ...
Margaret A. Hines, Lisa A. Taneyhill
wiley +1 more source
International Journal of Molecular Sciences, 2017 Nerve growth factor (NGF) promotes the survival and differentiation of neurons. NGF is initially synthesized as a precursor, proNGF, which is the predominant form in the central nervous system.
Maria S. Ioannou, M. Fahnestock
semanticscholar +1 more source
Low Density Limit of BCS Theory and Bose-Einstein Condensation of Fermion Pairs [PDF]
, 2011 We consider the low density limit of a Fermi gas in the BCS approximation. We show that if the interaction potential allows for a two-particle bound state, the system at zero temperature is well approximated by the Gross-Pitaevskii functional, describing
A.J. Leggett +21 more
core +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.Ferroptosis, a controlled cell death, is driven by iron and characterized by reactive oxygen species and lipid peroxidation. The impact of lipid peroxides, GSH/GPX4, and iron metabolism–targeting small molecule inhibitors is discussed. Nucleic acids, proteins, and phytochemicals are implicated as inhibitors of ferroptosis.
Anwar Ali +10 more
wiley +1 more source
Functional expression of TrkA receptors in hippocampal neurons
Journal of Neuroscience Research, 1998 Nerve growth factor (NGF) initiates its biological effects by promoting the dimerization and activation of the tyrosine kinase receptor TrkA. The requirements for NGF signaling through the TrkA receptor have been defined extensively from studies in immortalized cells, involving transfection of NIH 3T3, COS, and PC12 cells.
Aibel, Lani +3 more
openaire +4 more sources
, 2019 To exploit the benefits of massive multiple-input multiple-output (M-MIMO) technology in scenarios where base stations (BSs) need to be cheap and equipped with simple hardware, the computational complexity of classical signal processing schemes for ...
Abrao, Taufik +2 more
core +1 more source
Bex3 dimerization regulates NGF-dependent neuronal survival and differentiation by enhancing trkA gene transcription [PDF]
, 2017 The development of the nervous system is a temporally and spatially coordinated process that relies on the proper regulation of the genes involved. Neurotrophins and their receptors are directly responsible for the survival and differentiation of sensory
Anta, Begoña +6 more
core +1 more source
Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cells [PDF]
International Journal of Cancer, 2013 High levels of the NTRK1/TrkA receptor are expressed in low‐stage neuroblastomas, which are characterized by a good patient prognosis and often undergo spontaneous regression. In addition to apoptosis, tumor‐immune responses might contribute to this regression.
Pajtler, Kristian +10 more
openaire +4 more sources