Results 111 to 120 of about 34,874 (291)

Novel transcripts reveal a complex structure of the human TRKA gene and imply the presence of multiple protein isoforms [PDF]

, 2015
Publisher Copyright: © 2015 Luberg et al.Background: Tropomyosin-related kinase A (TRKA) is a nerve growth factor (NGF) receptor that belongs to the tyrosine kinase receptor family.
A Bonacchi, A Eggert, A Gong, A Jerónimo-Santos, A Salehi, A Tacconelli, A Tacconelli, AM Davies, AM Fagan, AR Farina, B Davidson, B Talcott, C Hock, C Lagadec, C Matrone, C Nassenstein, CR Sanna, CY Ni, D Chuderland, D Martin-Zanca, D Puehringer, DO Clary, DR Kaplan, E Díaz-Rodríguez, EJ Huang, Elina Aleksejeva, F Coulier, F Marmigère, FF Hefti, FL Watson, FS Lee, FS Lee, G Blobel, I Bongarzone, J Chen, J Jullien, JR Gomes, K Luberg, Kristi Luberg, L Minichiello, M Ohmichi, M Sepp, M-R Ho, MA Lemmon, MV Chao, ND Freedman, O Gimm, OG Vidaurre, P Dubus, PA Barker, R Rajagopal, R Schneider, R Urfer, Rahel Park, RM Stroud, RR Reinhardt, SD Ginsberg, SD Skaper, SE Calvo, SO Meakin, T Rantamäki, Tõnis Timmusk, V Freund-Michel, V Veeramachaneni, VA Flørenes, X Yao, X-Q Wang, Y Indo, Y Miura, Y Okazaki   +69 more
core   +2 more sources

Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature

Journal of Cutaneous Pathology, Volume 52, Issue 5, Page 367-373, May 2025.
ABSTRACT Spitz lesions display a set of genetic alterations that differ from classical melanocytic lesions: examples include mutations in HRAS and fusions involving ALK, ROS1, MET, MAP3K8, BRAF, and the NTRK genes. We present a Spitz spindle cell/Reed nevus with atypical junctional features and an NTRK2 translocation in a patient of unusual age.
Federico Scarfò, Emanuela Brunetto, Gilda Magliacane, Lorenza Pecciarini, Gerardo Ferrara, Nathalie Rizzo   +5 more
wiley   +1 more source

The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung

Scientific Reports, 2018
The neurotrophic tyrosine kinase receptor TrkA (NTRK1) and its ligand nerve growth factor (NGF) are emerging promoters of tumor progression. In lung cancer, drugs targeting TrkA are in clinical trials, but the clinicopathological significance of TrkA and
Fangfang Gao, Nathan Griffin, Sam Faulkner, C. Rowe, L. Williams, S. Roselli, R. Thorne, Aysha Ferdoushi, P. Jobling, M. Walker, H. Hondermarck   +10 more
semanticscholar   +1 more source

Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cells [PDF]

International Journal of Cancer, 2013
High levels of the NTRK1/TrkA receptor are expressed in low‐stage neuroblastomas, which are characterized by a good patient prognosis and often undergo spontaneous regression. In addition to apoptosis, tumor‐immune responses might contribute to this regression.
Pajtler, Kristian, Rebmann, Vera, Lindemann, Monika, Schulte, Johannes, Schulte, Stefanie, Stauder, Michael, Leuschner, Ivo, Schmid, Kurt Werner, Köhl, Ulrike, Schramm, Alexander, Eggert, Angelika   +10 more
openaire   +4 more sources

Randomized Kaczmarz Algorithm for Massive MIMO Systems with Channel Estimation and Spatial Correlation

, 2019
To exploit the benefits of massive multiple-input multiple-output (M-MIMO) technology in scenarios where base stations (BSs) need to be cheap and equipped with simple hardware, the computational complexity of classical signal processing schemes for ...
Abrao, Taufik, Filho, Jose Carlos Marinello, Rodrigues, Victor Croisfelt   +2 more
core   +1 more source

Mimicking the Dystrophic Cardiac Extracellular Environment through DystroGel

Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.
This research introduces DystroGel, a cutting‐edge biocompatible pathological hydrogel derived from decellularized dystrophic porcine heart tissue, suitable for tissue modeling applications. Rheological and proteomic analyses reveal structural and protein composition modifications, underscoring its unique properties.
Maila Chirivì, Fabio Maiullari, Marika Milan, Maria Grazia Ceraolo, Nicole Fratini, Alessandra Fasciani, Salma Bousselmi, Michael Stirm, Francesca Scalera, Francesca Gervaso, Michela Villa, Raffaello Viganò, Francesca Brambilla, Pierluigi Mauri, Elena De Falco, Dario Di Silvestre, Marco Costantini, Eckhard Wolf, Claudia Bearzi, Roberto Rizzi   +19 more
wiley   +1 more source

Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception

Journal of Neuroscience, 2018
Nerve growth factor (NGF) exerts multiple functions on target neurons throughout development. The recent discovery of a point mutation leading to a change from arginine to tryptophan at residue 100 in the mature NGFβ sequence (NGFR100W) in patients with ...
Kijung Sung, L. Ferrari, Wanlin Yang, ChiHye Chung, Xiaobei Zhao, Yingli Gu, Suzhen Lin, Kai Zhang, B. Cui, Matthew L. Pearn, M. Maloney, W. Mobley, J. Levine, Chengbiao Wu   +13 more
semanticscholar   +1 more source

p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. [PDF]

, 2013
The p75 neurotrophin receptor (p75(NTR)) is a member of the tumor necrosis factor receptor superfamily with a widespread pattern of expression in tissues such as the brain, liver, lung, and muscle.
Akassoglou, Katerina, Baeza-Raja, Bernat, Eckel-Mahan, Kristin, Ptácek, Louis J, Sassone-Corsi, Paolo, Tsigelny, Igor F, Vagena, Eirini, Zhang, Luoying   +7 more
core   +2 more sources

Bioactive Inorganic Materials for Innervated Multi‐Tissue Regeneration

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This review comprehensively summarizes the recent advancements of inorganic biomaterials for innervated multi‐tissue regeneration. It emphasizes the design principles of inorganic‐based material composites and their application in functional regeneration of nerves, bone, muscles, skin, and cavernous tissues.
Hongjian Zhang, Ziyi Zhao, Chengtie Wu
wiley   +1 more source

Expression of β‐NGF and high‐affinity NGF receptor (TrKA) in llama (Lama glama) male reproductive tract and spermatozoa

Molecular Reproduction and Development, 2018
β‐Nerve growth factor (β‐NGF) is a seminal plasma element, responsible for inducing ovulation in camelids. The main organ of β‐NGF production remains nondescript. The aims of this study were to (a) characterize gene expression and protein localization of
L. Sari, R. Zampini, M. Argañaraz, M. Carretero, F. G. Fumuso, D. Barraza, M. Ratto, S. Apichela   +7 more
semanticscholar   +1 more source