Results 111 to 120 of about 36,447 (274)
Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging
Pharmaceuticals, 2019 The tropomyosin receptor kinases family (TrkA, TrkB, and TrkC) supports neuronal growth, survival, and differentiation during development, adult life, and aging.
Ralf Schirrmacher +17 more
doaj +1 more source
Communications Biology, 2020 Using genetic code expansion, Zhao, Shi et al. generate light-sensitive tyrosine analogues to obtain insights into the activation of the NGF receptor, TrkA.
Shu Zhao +10 more
doaj +1 more source
an immunohistochemical study [PDF]
, 2016 Background The roles of the neurotrophins NGF (Neurotrophic growth factor) and BDNF (brain-derived neurotrophic factor) in neuronal growth and development are already known. Meanwhile, the neurotrophin receptors TrkA (tropomyosin related kinase A), TrkB,
Dewanto, Agung +6 more
core +1 more source
Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis [PDF]
, 2014 In normal ovarian function a controlled angiogenesis is essential. Several growth factors are involved in this process, such as the vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). The angiogenesis process in the normal ovary is a
Carmen Romero +3 more
core +1 more source
Biology Open, 2013 Summary PC12-27, a PC12 clone characterized by high levels of the transcription repressor REST and by very low mTORC2 activity, had been shown to be unresponsive to NGF, possibly because of its lack of the specific TrkA receptor.
Sara Negrini +2 more
doaj +1 more source
Runx1 promotes neuronal differentiation in dorsal root ganglion [PDF]
, 2012 Transcription factor Runx1 controls the cell type specification of peptidergic and nonpeptidergic nociceptive dorsal root ganglion (DRG) neurons by repressing TrkA and calcitonin gene-related peptide (CGRP) expression and activating Ret expression during
Kobayashi Azusa +8 more
core +1 more source
High Resolution Mapping of the Binding Site of TrkA for Nerve Growth Factor and TrkC for Neurotrophin-3 on the Second Immunoglobulin-like Domain of the Trk Receptors [PDF]
, 1998 Roman Urfer +5 more
openalex +1 more source
Shugan Jiangni Hewei Granule regulates synaptic plasticity in central sensitization via NGF/TrkA Signaling Pathways in psychological stress rats with nonerosive reflux disease [PDF]
, 2022 Guang Bai +4 more
openalex +1 more source
NGF - the TrkA to successful pain treatment.
Journal of pain research, 2012 Chronic pain arising from various pathological conditions such as osteoarthritis, low back or spinal injuries, cancer, and urological chronic pelvic pain syndromes presents significant challenges in diagnosis and treatment. Specifically, since the underlying cause of these pain syndromes is unknown or heterogeneous, physicians diagnose and treat ...
Kumar, Vinayak, Mahal, Brandon
openaire +3 more sources
PLoS ONE, 2019 The human hair follicle is a neuroendocrine mini-organ that can be used to study aging processes in vitro. Neurotrophins maintain homeostasis in hair biology via the Trk-family of receptors. TrkA, the high affinity receptor for nerve growth factor (NGF),
Remo Campiche +3 more
doaj +1 more source