Results 11 to 20 of about 21,086 (158)

EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression

Cell Communication and Signaling, 2021
Background During pregnancy, trophoblast cell invasion needs to be finely controlled. Aberrant trophoblast cell invasion is associated with placental diseases.
Lanlan Fang, Yibo Gao, Zhen Wang, Yuxi Li, Yang Yan, Ze Wu, Jung-Chien Cheng, Ying-Pu Sun   +7 more
doaj   +1 more source

Oxygen as modulator of trophoblast invasion [PDF]

Journal of Anatomy, 2009
AbstractAt the time of blastocyst implantation the uterine spiral arteries have already undergone morphological changes in the absence of any extravillous trophoblast invasion. Only 2 weeks after implantation, extravillous trophoblast cells develop and come into first contact with decidual tissues.
Berthold, Huppertz, Martin, Gauster, Kristina, Orendi, Julia, König, Gerit, Moser   +4 more
openaire   +2 more sources

Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice. [PDF]

PLoS ONE, 2015
The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Trophoblast cell proliferation, migration and invasion into the endometrium are fundamental events in the initiation
Amy Winship, Jeanne Correia, Jian-Guo Zhang, Nicos A Nicola, Evdokia Dimitriadis   +4 more
doaj   +1 more source

Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells

Brazilian Journal of Medical and Biological Research, 2023
Inadequate invasion and excessive apoptosis of trophoblast cells are associated with the development of preeclampsia. Vitamin D deficiency in pregnant women may lead to an increased risk of preeclampsia.
Xiaoyu Tian, Lili Zheng, Jing Ma, Ying Xu, Yulin Zhang, Yalei Pi   +5 more
doaj   +1 more source

KRT18 regulates trophoblast cell migration and invasion which are essential for embryo implantation

Reproductive Biology and Endocrinology, 2023
Female infertility is a worldwide concern that impacts the quality of life and well-being of affected couples. Failure of embryo implantation is a major cause of early pregnancy loss and is precisely regulated by a programmed molecular mechanism.
Xiaoling Liang, Xiaoxiao Qiu, Yana Ma, Wenzhi Xu, Sijia Chen, Peipei Zhang, Mengying Liu, Xiaona Lin   +7 more
doaj   +1 more source

Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage

Frontiers in Immunology, 2021
An appropriate development of the placenta consisting of trophoblast cell migration, invasion, proliferation, and apoptosis, is essential to establishing and maintaining a successful pregnancy.
Jiayu Wang, Jinli Ding, Sainan Zhang, Xin Chen, Sisi Yan, Yan Zhang, Tailang Yin   +6 more
doaj   +1 more source

Does malaria affect placental development? Evidence from in vitro models. [PDF]

PLoS ONE, 2013
BACKGROUND:Malaria in early pregnancy is difficult to study but has recently been associated with fetal growth restriction (FGR). The pathogenic mechanisms underlying malarial FGR are poorly characterized, but may include impaired placental development ...
Alexandra J Umbers, Danielle I Stanisic, Maria Ome, Regina Wangnapi, Sarah Hanieh, Holger W Unger, Leanne J Robinson, Elvin Lufele, Francesca Baiwog, Peter M Siba, Christopher L King, James G Beeson, Ivo Mueller, John D Aplin, Jocelyn D Glazier, Stephen J Rogerson   +15 more
doaj   +1 more source

Glycodelin-A as a modulator of trophoblast invasion [PDF]

Human Reproduction, 2009
Trophoblast invasion is crucial to placentation. The relationship between decidual glycodelin-A and trophoblast invasion is not known.Invasiveness of First trimester extravillous cytotrophoblast-1 (TEV-1) cell line, TEV-1, cells was determined by trans-well invasion assay.
Seppala, M, Ho, PC, Yeung, WSB, Koistinen, H, Koistinen, R, Lee, KF, Lee, CL, Chung, MK, Chiu, PCN, Lam, KKW   +9 more
openaire   +4 more sources

Serum amyloid A in the placenta and its role in trophoblast invasion. [PDF]

PLoS ONE, 2014
The serum amyloid A (SAA) protein is known to function in the acute phase response and immunoregulation. Recently, SAA has been shown to be involved in cell proliferation, differentiation and migratory behavior in different cell types. Here, we evaluated
Silvana Sandri, Alexandre Urban Borbely, Isabella Fernandes, Edson Mendes de Oliveira, Franciele Hinterholz Knebel, Rodrigo Ruano, Marcelo Zugaib, Fabiola Filippin-Monteiro, Estela Bevilacqua, Ana Campa   +9 more
doaj   +1 more source

A Proteomics-Based Identification of the Biological Networks Mediating the Impact of Epigallocatechin-3-Gallate on Trophoblast Cell Migration and Invasion, with Potential Implications for Maternal and Fetal Health

Proteomes, 2023
Trophoblast migration and invasion play crucial roles in placental development. However, the effects of (-)-epigallocatechin-3-gallate (EGCG) on trophoblast cell functions remain largely unexplored.
Yueh-Chung Chen, Chen-Chung Liao, Hao-Ai Shui, Pei-Hsuan Huang, Li-Jane Shih   +4 more
doaj   +1 more source