Results 21 to 30 of about 21,086 (158)
Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells. [PDF]
PLoS ONE, 2014 The precise regulation of extravillous trophoblast invasion of the uterine wall is a key process in successful pregnancies. Kisspeptin (KP) has been shown to inhibit cancer cell metastasis and placental trophoblast cell migration.
Víctor A Francis +4 more
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RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress
Clinical and Experimental Obstetrics & Gynecology, 2022 Background: Previous studies shown that RNA binding motif proteins (RBM) participate in regulating various physiological processes such as cell autophagy, proliferation, and apoptosis, and are abnormally highly expressed in placental trophoblast cells ...
Xiao Chen +4 more
doaj +1 more source
Regulation of Trophoblast Invasion — A Workshop Report [PDF]
Placenta, 2008 Trophoblast invasion during placental development helps to establish efficient physiological exchange between maternal and fetal circulatory systems. Trophoblast stem cells differentiate into multiple subtypes, including some that are highly invasive.
Knofler M +4 more
openaire +6 more sources
Cellular Physiology and Biochemistry, 2014 Background/Aims: The invasion of trophoblast cells into the maternal uterine decidua is critical for normal placentation, establishment of pregnancy and maintenance of fetal growth in humans.
Rui-Zhe Jia +6 more
doaj +1 more source
Isolation of Primary Mouse Trophoblast Cells and Trophoblast Invasion Assay [PDF]
Journal of Visualized Experiments, 2012 The placenta is responsible for the transport of nutrients, gasses and growth factors to the fetus, as well as the elimination of wastes. Thus, defects in placental development have important consequences for the fetus and mother, and are a major cause of embryonic lethality.
Kathleen A, Pennington +2 more
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CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion
Frontiers in Immunology, 2021 Recurrent spontaneous abortion (RSA) affects 5% of childbearing-age women worldwide. Inadequate trophoblast invasion is one of the main reasons for the development of RSA; however, the underlying molecular mechanisms for RSA have not been fully ...
Sainan Zhang +5 more
doaj +1 more source
Effects of selenium on the survival and invasion of trophoblasts [PDF]
Clinical and Experimental Reproductive Medicine, 2018 Placental oxidative stress is known to be a factor that contributes to pregnancy failure. The aim of this study was to determine whether selenium could induce antioxidant gene expression and regulate invasive activity and mitochondrial activity in trophoblasts, which are a major cell type of the placenta.To understand the effects of selenium on ...
Na, Jee Yoon +4 more
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Epigenetic control of cell invasion – the trophoblast model
Biomolecular Concepts, 2012 Trophoblast implantation and placentation allow the survival of the young embryo and its normal development inside the uterus. In order for these processes to function properly, the trophoblast has to undergo a series of characteristic changes that lead ...
Serman Alan +3 more
doaj +1 more source
Trophoblast Migration with Different Oxygen Levels in a Gel-Patterned Microfluidic System
Micromachines, 2022 In the placenta, substances such as nutrients, oxygen, and by-products are exchanged between the mother and the fetus, and the proper formation of the placenta determines the success of pregnancy, including the growth of the fetus.
Gun Ko, Tae-Joon Jeon, Sun Min Kim
doaj +1 more source
Effects of adiponectin on human trophoblast invasion [PDF]
Journal of Endocrinology, 2010 Adiponectin is an adipokine with insulin-sensitizing, anti-inflammatory, anti-atherogenic, and anti-proliferative effects. The expression of specific adiponectin receptors in the placenta and in the endometrium suggests a role for this cytokine in placental development, but this role has not yet been elucidated. The invasion of trophoblast cells during
Benaitreau, Delphine +7 more
openaire +4 more sources