Results 1 to 10 of about 951 (106)
cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction [PDF]
Respiratory Research, 2018 Background The nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) signaling pathway, plays a critical role in the pathogenesis of pulmonary arterial hypertension (PAH); however, its exact molecular mechanism remains ...
Lihui Zou +7 more
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The binding dynamics of tropomyosin on actin [PDF]
Biophys. J. 81, 3146-3155 (2001), 2001 We discuss a theoretical model for the cooperative binding dynamics of tropomyosin to actin filaments. Tropomyosin binds to actin by occupying seven consecutive monomers. The model includes a strong attraction between attached tropomyosin molecules. We start with an empty lattice and show that the binding goes through several stages.
arxiv +7 more sources
Frontiers in Cell and Developmental Biology, 2023 Tropomyosin is generally known as an actin-binding protein that regulates actomyosin interaction and actin filament stability. In metazoans, multiple tropomyosin isoforms are expressed, and some of them are involved in generating subpopulations of actin ...
Shoichiro Ono +7 more
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Current Biology, 2017 The actin cytoskeleton provides not only the underpinning for cell architecture but also mechanical force and the ability to drive movement of cells and their organelles. It is tempting to think of it simply as a set of stable structural elements, but nothing could be further from the truth.
Peter W, Gunning, Edna C, Hardeman
openaire +2 more sources
Micro-mechanical response and power-law exponents from the longitudinal fluctuations of F-actin solutions [PDF]
Soft Matter, 2023,19, 3652-3660, 2022 We investigate the local fluctuations of filamentous actin (F-actin), with focus on the skeletal thin filament, using single-particle optical trapping interferometry. This experimental technique allows us to detect the Brownian motion of a tracer bead immersed in a complex fluid with nanometric resolution at the microsecond time-scale.
arxiv +1 more source
Clinical and Molecular Allergy, 2021 Background Mugwort and house dust mite (HDM) are two of the most common inhalant allergens in Asia, however, whether mugwort affects polysensitized HDM+ allergic rhinitis (AR) patients has not been elucidated.
Su Duan +11 more
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Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension [PDF]
PeerJ, 2013 Assembly of the actin cytoskeleton is an important part of formation of neurites in developing neurons. Tropomodulin, a tropomyosin-dependent capping protein for the pointed end of the actin filament, is one of the key players in this process ...
Natalia Moroz +3 more
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Digestion of tropomyosin with trypsin [PDF]
FEBS Letters, 1977 Tropomyosin is a rod-like a-helical protein composed of two similar subunits in a coiled-coil configuration. It is situated in the grooves of the F-actin strands and with troponin constitutes the regulatory-complex of vertebrate striated muscle. The sequence of the tropomyosin subunit has been determined by Stone, et al. [ 11.
Witold Drabikowski, A. Gorecka
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Food and Agricultural Immunology, 2023 The aim of this study was evaluated the effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages based on chitosan using the ELISA. The analysed protein was the tropomyosin.
L. Havlová +8 more
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Multisyringe Flow Injection Analysis of Tropomyosin Allergens in Shellfish Samples
Molecules, 2021 This paper presents the development and the application of a multisyringe flow injection analysis system for the fluorimetric determination of the major heat-stable known allergen in shrimp, rPen a 1 (tropomyosin).
Bruno Coulomb +4 more
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