Results 1 to 10 of about 36,700 (241)

Tropomyosin-based cross-reactivity and asymptomatic shellfish sensitization in patients with perennial allergy [PDF]

Frontiers in Allergy
BackgroundMite, cockroach, and shellfish (crab, clam, and shrimp) proteins share allergenic epitopes. The determination of specific IgE (sIgE) against cockroach (Blattella germanica, relevant in asthma) and shellfish allergens (relevant in food allergy ...
Moritz Maximilian Hollstein, Marie Charlotte Schuppe, Katharina Klara Hahn, Prasad Dasari, Susann Forkel, Caroline Beutner, Timo Buhl, Timo Buhl   +7 more
doaj   +2 more sources

Respiratory symptoms, sensitisation and occupational exposure in the shrimp processing industry [PDF]

Frontiers in Allergy
IntroductionShellfish processing workers are highly susceptible to respiratory illnesses such as allergies and asthma. This study examined respiratory symptoms and biomarkers of allergy and asthma in Norwegian shrimp processing plant workers and ...
Fikirte Debebe Zegeye, Fikirte Debebe Zegeye, Pål Graff, Miriam Grgic, Steen Mollerup, Anani Komlavi Afanou, Berit Elisabeth Bang, Berit Elisabeth Bang, Karl-Christian Nordby, Anne Straumfors, Johanna Samulin Erdem   +10 more
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RNA-seq analysis of shrimp tropomyosin-induced allergic reactions through PI3K/Akt pathway [PDF]

Frontiers in Nutrition
IntroductionTropomyosin (TM) is the primary allergen in Litopenaeus vannamei, which usually causes allergic reactions that may be health or even life-threatening for consumers. Therefore, exploring the sensitization mechanism is of great significance for
Yanchu Li, Yanchu Li, Yuying Yang, Junyao Li, Rui Guo, Zhiqiang Niu, Weicheng Hu, Shucheng Liu, Shucheng Liu, Shuai Wei, Shuai Wei   +10 more
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Tropomyosin Isoforms Segregate into Distinct Clusters on Single Actin Filaments [PDF]

Biomolecules
Tropomyosins (Tpms) are rod-shaped proteins that interact head-to-tail to form a continuous polymer along both sides of most cellular actin filaments. Head-to-tail interaction between adjacent Tpm molecules and the formation of an overlap complex between
Peyman Obeidy, Thomas Sobey, Philip R. Nicovich, Adelle C. F. Coster, Elvis Pandzic   +4 more
doaj   +2 more sources

Mutual dependence between tropomodulin and tropomyosin in the regulation of sarcomeric actin assembly in Caenorhabditis elegans striated muscle

European Journal of Cell Biology, 2022
Tropomodulin and tropomyosin are important components of sarcomeric thin filaments in striated muscles. Tropomyosin decorates the side of actin filaments and enhances tropomodulin capping at the pointed ends of the filaments.
Shoichiro Ono, Mario Lewis, Kanako Ono
doaj   +1 more source

Alternative splicing of a single exon causes a major impact on the affinity of Caenorhabditis elegans tropomyosin isoforms for actin filaments

Frontiers in Cell and Developmental Biology, 2023
Tropomyosin is generally known as an actin-binding protein that regulates actomyosin interaction and actin filament stability. In metazoans, multiple tropomyosin isoforms are expressed, and some of them are involved in generating subpopulations of actin ...
Shoichiro Ono, Shoichiro Ono, Eichi Watabe, Keita Morisaki, Kanako Ono, Kanako Ono, Hidehito Kuroyanagi, Hidehito Kuroyanagi   +7 more
doaj   +1 more source

Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

iScience, 2022
Summary: The effects of N-terminal acetylation of the high molecular weight tropomyosin isoforms Tpm1.6 and Tpm2.1 and the low molecular weight isoforms Tpm1.12, Tpm3.1, and Tpm4.2 on the actin affinity and the thermal stability of actin-tropomyosin ...
Theresia Reindl, Sven Giese, Johannes N. Greve, Patrick Y. Reinke, Igor Chizhov, Sharissa L. Latham, Daniel P. Mulvihill, Manuel H. Taft, Dietmar J. Manstein   +8 more
doaj   +1 more source

Editorial: Physiology of human myopathies [PDF]

Frontiers in Physiology
Aldrin V. Gomes, Jose R. Pinto, Danuta Szczesna-Cordary   +2 more
doaj   +2 more sources

Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension [PDF]

PeerJ, 2013
Assembly of the actin cytoskeleton is an important part of formation of neurites in developing neurons. Tropomodulin, a tropomyosin-dependent capping protein for the pointed end of the actin filament, is one of the key players in this process ...
Natalia Moroz, Laurent Guillaud, Brinda Desai, Alla S. Kostyukova   +3 more
doaj   +2 more sources

Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite

Clinical and Molecular Allergy, 2021
Background Mugwort and house dust mite (HDM) are two of the most common inhalant allergens in Asia, however, whether mugwort affects polysensitized HDM+ allergic rhinitis (AR) patients has not been elucidated.
Su Duan, Limin Zhao, Yuling Zhang, Nan Zhang, Ming Zheng, Qiqi Wang, Xu Zhang, Xiangdong Wang, Sun Ying, Claus Bachert, Luo Zhang, Feng Lan   +11 more
doaj   +1 more source