Results 31 to 40 of about 59,695 (281)

The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy [PDF]

, 2008
Background: Hypertrophic (HCM) and dilated (DCM) cardiomyopathies results from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2).
Ahmad, F, Banerjee, SK, Conner, DA, Huang, XN, Janczewski, AM, Keller, BB, Lage, ML, Mathier, MA, Moskowitz, IP, Perez-Atayde, AR, Rager, J, Saba, S, Seidman, CE, Seidman, JG, Shroff, SG, Smith, SH, Tinney, JP, Tobita, K   +17 more
core   +9 more sources

Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

iScience, 2022
Summary: The effects of N-terminal acetylation of the high molecular weight tropomyosin isoforms Tpm1.6 and Tpm2.1 and the low molecular weight isoforms Tpm1.12, Tpm3.1, and Tpm4.2 on the actin affinity and the thermal stability of actin-tropomyosin ...
Theresia Reindl, Sven Giese, Johannes N. Greve, Patrick Y. Reinke, Igor Chizhov, Sharissa L. Latham, Daniel P. Mulvihill, Manuel H. Taft, Dietmar J. Manstein   +8 more
doaj  

Distortion of the Actin A-Triad Results in Contractile Disinhibition and Cardiomyopathy

Cell Reports, 2017
Striated muscle contraction is regulated by the movement of tropomyosin over the thin filament surface, which blocks or exposes myosin binding sites on actin.
Meera C. Viswanathan, William Schmidt, Michael J. Rynkiewicz, Karuna Agarwal, Jian Gao, Joseph Katz, William Lehman, Anthony Cammarato   +7 more
doaj   +1 more source

Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]

, 2014
The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Balasubramanian, Breitsprecher, Bryce, Bugyi, Chang, Coulton, Creed, Daniel A. East, Daniel P. Mulvihill, East, Feierbach, Galkin, Grallert, Gunning, Huang, Karagiannis, Martin, Martin, Mata, Matthew Johnson, Mulvihill, Papp, Scott, Skau, Skoumpla, Stark, Tojkander, Ujfalusi, Ujfalusi, Wawro   +29 more
core   +1 more source

Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies [PDF]

, 2014
Mutations affecting skeletal muscle isoforms of the tropomyosin genes may cause nemaline myopathy, cap myopathy, core-rod myopathy, congenital fiber-type disproportion, distal arthrogryposes, and Escobar syndrome.
Barnerias, Christine, Beggs, Alan H., Bertini, Enrico, Ceyhan-Birsoy, Özge, Cintas, Pascal, Clarke, Nigel F., de Visser, Marianne, Eymard, Bruno, Frydman, Moshe, Gerard, Marion, Gilbert-Dussardier, Brigitte, Grönholm, Mikaela, Hogue, Jacob S., Kang, Peter B., Klinge, Lars, Kolski, Hanna, Laing, Nigel G., Lehtokari, Vilma-Lotta, Lochmüller, Hans, Longman, Cheryl, Magy, Laurent, Manel, Véronique, Marston, Steven, Marttila, Minttu, Mayer, Michèle, Mercuri, Eugenio, Monnier, Nicole, North, Kathryn N., Nowak, Kristen, Nyman, Tuula A., Pelin, Katarina, Peudenier-Robert, Sylviane, Pihko, Helena, Probst, Frank J., Reisin, Ricardo, Stewart, Willie, Taratuto, Ana Lia, Wallgren-Pettersson, Carina, Wilichowski, Ekkehard, Winder, Tom L., Winer, John   +40 more
core   +1 more source

Gene Cloning and Prokaryotic Expression of the Allergen Tropomyosin from Macrobrachium nipponense [PDF]

Shipin Kexue
To explore substitutes for natural tropomyosin as basic materials for the diagnosis and treatment of shrimp allergy, total RNA was extracted from Macrobrachium nipponense, and the full-length sequence of the tropomyosin gene was cloned by rapid ...
LUO Yeqing, ZHENG Shuangyan, SUN Yaobin, CHEN Jiao, LIU Xin, CHEN Hongbing, XIE Yanhai
doaj   +1 more source

Dynamics of tropomyosin in muscle fibers as monitored by saturation transfer EPR of bi-functional probe. [PDF]

PLoS ONE, 2011
The dynamics of four regions of tropomyosin was assessed using saturation transfer electron paramagnetic resonance in the muscle fiber. In order to fully immobilize the spin probe on the surface of tropomyosin, a bi-functional spin label was attached to ...
Roni F Rayes, Tamás Kálai, Kálmán Hideg, Michael A Geeves, Piotr G Fajer   +4 more
doaj   +1 more source

Changing the IgE Binding Capacity of Tropomyosin in Shrimp through Structural Modification Induced by Cold Plasma and Glycation Treatment

Foods, 2023
Tropomyosin (TM) is the major allergen of shrimp (Penaeus chinensis). Previous studies showed that separate cold plasma or glycation have their drawback in reducing allergenicity of TM, including effectiveness and reliability. In the current study, a new
Feng-Qi Wang, Jun-Hu Cheng, Kevin M. Keener   +2 more
doaj   +1 more source

Co-Immunization Efficacy of Recombinant Antigens against Rhipicephalus microplus and Hyalomma anatolicumTick Infestations

Pathogens, 2023
The immunoprophylactic management of ticks is the most effective option to control tick infestations and counter spread the acaricide resistance problem worldwide.
Balasamudram Chandrasekhar Parthasarathi, Binod Kumar, S. K. Bhure, Anil Kumar Sharma, Manisha, Gaurav Nagar, Sachin Kumar, Abhijit Nandi, Haranahally Vasanthachar Manjunathachar, Gajanan M. Chigure, Mukesh Shakya, Muthu Sankar, José de la Fuente, Srikant Ghosh   +13 more
doaj   +1 more source

Allergenicity Reduction of Antarctic Krill (Euphausia superba) Tropomyosin through Glycosylation Modification

Shipin gongye ke-ji
Antarctic krill (Euphausia superba) was a premium protein resource. However, its strong allergenicity remained a problem that awaited resolution.
Shuqi ZHANG, Shuya WANG, Shuqi JIA, Kexin LIU, Na SUN   +4 more
doaj   +1 more source