Results 31 to 40 of about 36,700 (241)

Multisyringe Flow Injection Analysis of Tropomyosin Allergens in Shellfish Samples

Molecules, 2021
This paper presents the development and the application of a multisyringe flow injection analysis system for the fluorimetric determination of the major heat-stable known allergen in shrimp, rPen a 1 (tropomyosin).
Bruno Coulomb, Fabien Robert-Peillard, Najib Ben Ali Gam, Salwa Sadok, Jean-Luc Boudenne   +4 more
doaj   +1 more source

A Proteomic Study of Atherosclerotic Plaques in Men with Coronary Atherosclerosis

Diagnostics, 2019
Background: To study the changes in protein composition of atherosclerotic plaques at different stages of their development in coronary atherosclerosis using proteomics.
Ekaterina M. Stakhneva, Irina A. Meshcheryakova, Evgeny A. Demidov, Konstantin V. Starostin, Evgeny V. Sadovski, Sergey E. Peltek, Michael I. Voevoda, Alexander M. Chernyavskii, Alexander M. Volkov, Yuliya I. Ragino   +9 more
doaj   +1 more source

Identification of the pan-allergen tropomyosin from the common bed bug (Cimex lectularius)

Scientific Reports
Tropomyosin is a muscle contraction protein documented across all animal life. Despite its ubiquity, its unique structure in invertebrates leads to allergic responses in humans that vertebrate tropomyosin does not.
Johnalyn M. Gordon, Zachary C. DeVries
doaj   +1 more source

Development of a sandwich ELISA and immunochromatographic strip for the detection of shrimp tropomyosin

Food and Agricultural Immunology, 2019
Shrimp tropomyosin is one of the most important causes of shellfish allergy. The objective of this study was to develop a highly sensitive and specific immunoassay for the detection of shrimp tropomyosin in food.
Lu Zeng, Shanshan Song, Qiankun Zheng, Pengjie Luo, Xiaoling Wu, Hua Kuang   +5 more
doaj   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Transglutaminase-catalysed cross-linking eliminates Penaeus chinensis tropomyosin allergenicity by altering protein structure

Food and Agricultural Immunology, 2019
Transglutaminase (TG) is a major food processing enzyme that induces protein cross-linking. Tropomyosin (TM) is a major shellfish allergen that is responsible for at least 80% of the shrimp allergic incidents.
Linglin Fu, Saiqiao Ni, Chong Wang, Yanbo Wang   +3 more
doaj   +1 more source

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

Cytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker, Karen Baker, Marina Ezcurra, Philippe P. Laissue, Lin Wang, Michael A. Geeves, Jennifer M. Tullet, Daniel P. Mulvihill   +7 more
wiley   +1 more source

Tropomyosin allergen from freshwater and marine water crabs: Identification, structural-physicochemical, rheological and allergenic characterization

Applied Food Research
The aim of the present investigation was to purify and characterize highly allergenic tropomyosin from economically important crab species of freshwater and marine sources.
Omgy Neha, Anandan Rangasamy, Sankar T․V․, Vijay Kumar Reddy Surasani, Lalitha Gnanasekaran, Saranya Vinayagam, Thanigaivel Sundaram, Ranjana Devi Mutum, Turki Kh. Faraj, Abdulwahed Fahad Alrefaei, Pavan Kumar Dara, Maximilian Lackner   +11 more
doaj   +1 more source

Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins

Frontiers in Immunology, 2018
BackgroundIt has been shown earlier that there is a rise in the levels of autoantibodies and T cell response to cytoskeletal proteins in leprosy. Our group recently demonstrated a rise in both T and B cell responses to keratin and myelin basic protein in
Itu Singh, Asha Ram Yadav, Keshar Kunja Mohanty, Kiran Katoch, Prashant Sharma, Vinay Kumar Pathak, Deepa Bisht, Umesh D. Gupta, Utpal Sengupta   +8 more
doaj   +1 more source

The Conformational Stabilities of Tropomyosins [PDF]

Australian Journal of Biological Sciences, 1976
The stability to denaturation by heat and guanidine hydrochloride of seven vertebrate (including skeletal, cardiac and smooth muscle) tropomyosins and three invertebrate tropomyosins was examined. The transition profiles were discontinuous and in many cases distinct plateaux were observed which indicated the presence of unique partially unfolded states
openaire   +3 more sources