Results 31 to 40 of about 76,365 (337)

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

open access: yes, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Gene Cloning and Prokaryotic Expression of the Allergen Tropomyosin from Macrobrachium nipponense [PDF]

open access: yesShipin Kexue
To explore substitutes for natural tropomyosin as basic materials for the diagnosis and treatment of shrimp allergy, total RNA was extracted from Macrobrachium nipponense, and the full-length sequence of the tropomyosin gene was cloned by rapid ...
LUO Yeqing, ZHENG Shuangyan, SUN Yaobin, CHEN Jiao, LIU Xin, CHEN Hongbing, XIE Yanhai
doaj   +1 more source

In Silico Prediction of Cross-Reactive Epitopes of Tropomyosin from Shrimp and Other Arthropods Involved in Allergy

open access: yesMolecules, 2022
Tropomyosin in shellfish is considered a major cross-reactive allergen in house dust mites and cockroaches; however, the specific epitopes have not been elucidated. Therefore, this study aimed to identify the consensus antigenic determinant among shrimp,
Jirakrit Saetang   +2 more
doaj   +1 more source

Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus [PDF]

open access: yes, 2011
Caldesmon (CaD) is an important actin modulator that associates with actin filaments to regulate cell morphology and motility. Although extensively studied in cultured cells, there is little functional information regarding the role of CaD in migrating ...
Bronner-Fraser, Marianne   +2 more
core   +2 more sources

Troponin T3 regulates nuclear localization of the calcium channel Cavβ1a subunit in skeletal muscle [PDF]

open access: yes, 2015
The voltage-gated calcium channel (Cav) β1a subunit (Cavβ1a) plays an important role in excitation-contraction coupling (ECC), a process in the myoplasm that leads to muscle-force generation. Recently, we discovered that the Cavβ1a subunit travels to the
Delbono, Osvaldo   +7 more
core   +2 more sources

Phosphoregulation of tropomyosin is crucial for actin cable turnover and division site placement

open access: yesJournal of Cell Biology, 2019
Palani et al. reveal a new mechanism by which the F-actin binding protein tropomyosin is regulated. They find that phosphorylation of tropomyosin reduces its affinity for F-actin, allowing the competing Adf1 to bind and sever actin filaments.
S. Palani   +10 more
semanticscholar   +1 more source

Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics

open access: yesProteomes, 2019
The mass spectrometric analysis of skeletal muscle proteins has used both peptide-centric and protein-focused approaches. The term ‘top-down proteomics’ is often used in relation to studying purified proteoforms and their post-translational ...
Paul Dowling   +3 more
doaj   +1 more source

Effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages containing chitosan, by the ELISA method

open access: yesFood and Agricultural Immunology, 2023
The aim of this study was evaluated the effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages based on chitosan using the ELISA. The analysed protein was the tropomyosin.
L. Havlová   +8 more
doaj   +1 more source

Effect of Heat Processing on IgE Reactivity and Cross‐Reactivity of Tropomyosin and Other Allergens of Asia‐Pacific Mollusc Species: Identification of Novel Sydney Rock Oyster Tropomyosin Sac g 1

open access: yesMolecular Nutrition & Food Research, 2018
Scope Shellfish allergy is an increasing global health priority, frequently affecting adults. Molluscs are an important shellfish group causing food allergy but knowledge of their allergens and cross‐reactivity is limited.
J. Rolland   +8 more
semanticscholar   +1 more source

Allergenicity Reduction of Antarctic Krill (Euphausia superba) Tropomyosin through Glycosylation Modification

open access: yesShipin gongye ke-ji
Antarctic krill (Euphausia superba) was a premium protein resource. However, its strong allergenicity remained a problem that awaited resolution.
Shuqi ZHANG   +4 more
doaj   +1 more source

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