Results 21 to 30 of about 6,764,388 (368)
The effect of proteolytic enzymes on the troponin complex [PDF]
FEBS Letters, 1971 W. Drabikowski +4 more
openalex +4 more sources
Expression and Purification of mutant troponin complex
Seibutsu Butsuri, 2000 Keiji Murakami +4 more
openalex +3 more sources
Dynamics of a Troponin Chimera Reproduce the Effects of Calcium on the Troponin Complex [PDF]
Biophysical Journal, 2012 In striated muscle, contraction is regulated in a Ca2+-dependent manner by the three subunits of the troponin complex. Troponin I (TnI) inhibits actomyosin ATPase in the absence of calcium; Ca2+ binding to troponin C (TnC) causes conformational changes that alter the interaction between TnI and TnC, removing the inhibition. These conformational changes
Olivier Julien +5 more
openalex +2 more sources
Production, crystallization, and preliminary X‐ray analysis of rabbit skeletal muscle troponin complex consisting of troponin C and fragment (1‐47) of troponin I [PDF]
Protein Science, 1997 Yumiko Saijo +7 more
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Troponin Variants as Markers of Skeletal Muscle Health and Diseases
Frontiers in Physiology, 2021 Ca2+-regulated contractility is a key determinant of the quality of muscles. The sarcomeric myofilament proteins are essential players in the contraction of striated muscles.
Monica Rasmussen +2 more
doaj +1 more source
An in silico analysis of troponin I mutations in hypertrophic cardiomyopathy of Indian origin. [PDF]
PLoS ONE, 2013 Hypertrophic Cardiomyopathy (HCM) is an autosomal dominant disorder of the myocardium which is hypertrophied resulting in arrhythmias and heart failure leading to sudden cardiac death (SCD).
Gayatri Ramachandran +6 more
doaj +1 more source
Clinical Chemistry, 2022 Patient 1 was a 28-year-old Caucasian woman who presented with a 4-day history of chest pain to the same day emergency care unit at the Western General Hospital, Edinburgh, Scotland.
A. Bularga +7 more
semanticscholar +1 more source
Interaction of bepridil with the cardiac troponin C/troponin I complex [PDF]
FEBS Letters, 2001 We have investigated the binding of bepridil to calcium‐saturated cardiac troponin C in a cardiac troponin C/troponin I complex. Nuclear magnetic resonance spectroscopy and [15N,2H]cardiac troponin C permitted the mapping of bepridil‐induced amide proton chemical shifts. A single bepridil‐binding site in the regulatory domain was found with an affinity
Abusamhadneh, Ekram +5 more
openaire +2 more sources
Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. [PDF]
PLoS ONE, 2012 The contractile response of the heart can be altered by disease-related protein modifications to numerous contractile proteins. By utilizing an IAANS labeled fluorescent troponin C, [Formula: see text], we examined the effects of ten disease-related ...
Bin Liu +4 more
doaj +1 more source