Results 111 to 120 of about 18,800 (265)

Effect of metabolic syndrome and aging on Ca2+ dysfunction in coronary smooth muscle and coronary artery disease severity in Ossabaw miniature swine [PDF]

open access: yes, 2018
BACKGROUND: Metabolic syndrome (MetS) and aging are prevalent risk factors for coronary artery disease (CAD) and contribute to the etiology of CAD, including dysregulation of Ca2+ handling mechanisms in coronary smooth muscle (CSM).
Badin, Jill K.   +2 more
core   +1 more source

Erratum: Yao et al., “Involvement of TRPC Channels in CCL2-Mediated Neuroprotection against Tat Toxicity” [PDF]

open access: bronze, 2020
Honghong Yao   +8 more
openalex   +1 more source

Function and Regulation of Endothelin Type A Receptor–Operated Transient Receptor Potential Canonical Channels

open access: yesJournal of Pharmacological Sciences, 2011
.: The purpose of this study is to identify transient receptor potential canonical (TRPC) channels responsible for receptor-operated Ca2+ entry (ROCE) triggered by activation of endothelin type A receptor (ETAR) and to clarify the importance of ...
Takahiro Horinouchi   +6 more
doaj   +1 more source

TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses.

open access: yesPLoS Biology, 2019
Transient receptor potential (TRP) proteins form Ca2+-permeable, nonselective cation channels, but their role in neuronal Ca2+ homeostasis is elusive. In the present paper, we show that TRPC channels potently regulate synaptic plasticity by changing the ...
Yvonne Schwarz   +8 more
doaj   +1 more source

Activation of TRPC Cationic Channels by Mercurial Compounds Confers the Cytotoxicity of Mercury Exposure [PDF]

open access: bronze, 2011
Shang‐Zhong Xu   +5 more
openalex   +1 more source

TRPC3 and TRPC6 as molecular mediators of resistant hypertension and cardiac fibrosis: a new therapeutic frontier

open access: yesArterial Hypertension
Resistant hypertension remains a significant global health concern and is a major contributor to cardiovascular complications such as vascular dysfunction and cardiac fibrosis. Emerging evidence suggests that transient receptor potential canonical (TRPC)
Shobana Kumar   +5 more
doaj   +1 more source

Differential expression and hypoxic regulation of adenosine receptors and TRPC channels in the developing heart. [PDF]

open access: yes, 2012
Objectives: To characterize the modifications of gene expression of adenosine receptors (AR), TRPC channels, HIF-1α and iNOS during the early cardiogenesis in response to chronic hypoxia exposure. Methods: 4-day-old chick embryos were subjected in ovo to
Carrupt, M.
core  

Contribution of Zinc-Dependent Delayed Calcium Influx via TRPC5 in Oxidative Neuronal Death and its Prevention by Novel TRPC Antagonist [PDF]

open access: hybrid, 2018
Sang Eun Park   +18 more
openalex   +1 more source

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