Results 171 to 180 of about 7,904 (196)

Mechanism of Inhibition of TRPC Cation Channels by 2-Aminoethoxydiphenylborane

Molecular Pharmacology, 2005
We investigated the actions of the organoborane, 2-aminoethoxydiphenylborane (2APB), on Ca2+ signaling in wild-type human embryonic kidney (HEK) 293 cells and in HEK293 cells stably expressing canonical transient receptor potential (TRPC) channels. Previous reports have suggested that 2APB inhibits agonist activation of TRPC channels because of its ...
Jean-Philippe, Lievremont, Gary S, Bird, James W, Putney   +2 more
openaire   +2 more sources

The enigmatic TRPCs: multifunctional cation channels

Trends in Cell Biology, 2004
Abstract Canonical transient receptor potential (TRPC) channels are vertebrate homologs of the Drosophila photoreceptor channel. Considerable research has been carried out on the seven members of this family, particularly regarding their possible role in Ca 2+ entry.
openaire   +2 more sources

TRPC and SOC Cationic Channels in Vascular Smooth Muscle

Neurophysiology, 2003
D. J. Beech, S. Z. Xu, R. Flemming, D. McHugh, F. Zeng   +4 more
openaire   +1 more source

CX3CR1 positive myeloid cells differentially regulate atherosclerotic vascular smooth muscle contraction by plc dependent activation of transient receptor potential cation (TRPC) channels

Atherosclerosis, 2020
A. Kumar, R. Mcgeogh, H. Cassidy, H.A. Ebhardt, V. Sharma   +4 more
openaire   +1 more source

Cation Channels of the TRPC family Contribute to the Development of Retinopathy in the STZ Model

Canadian Journal of Diabetes, 2017
Robin Sachdeva, Dagmar Schumacher, Christin Matka, Ilka Mathar, Sarah Homberg, Ulrich Kriebspaula Stettner, Peter Nawroth, Hermann-Josef Gröne, Hans-Peter Hammes, Thomas Fleming, Marc Freichel   +10 more
openaire   +1 more source

Cation channels of the TRPC family contribute to development of nephropathy and retinopathy in the STZ model

Diabetologie und Stoffwechsel, 2015
M Freichel, D Schumacher, C Matka, I Mathar, U Kriebs, R Sachdeva, P Stettner, HP Hammes, HJ Gröne, P Nawroth, T Fleming   +10 more
openaire   +1 more source

Cation channels of the TRPC family contribute to development of nephropathy and retinopathy in the STZ model

Diabetologie und Stoffwechsel, 2016
D Schumacher, C Matka, R Sachdeva, N Dietrich, A Schlotterer, I Mathar, S Homberg, U Kriebs, P Stettner, PP Nawroth, HJ Gröne, HP Hammes, T Fleming, M Freichel   +13 more
openaire   +1 more source

W1354 Evidence for Functional TRPC Channels Underlying Non Selective Cation Currents in Mouse Nodose Ganglion Neurons

Gastroenterology, 2008
Sung Jin Park, Michael Beyak
openaire   +1 more source

Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine

Annual Review of Pharmacology and Toxicology, 2022
David J Wright, David J Beech, Piruthivi Sukumar   +2 more
exaly  

Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes

Neuron, 2022
Alexander Haupt, Dieter Bruns, Veit Flockerzi   +2 more
exaly