Results 31 to 40 of about 5,720 (153)
TRP Channels in Angiogenesis and Other Endothelial Functions
Frontiers in Physiology, 2018 Angiogenesis is the growth of blood vessels mediated by proliferation, migration, and spatial organization of endothelial cells. This mechanism is regulated by a balance between stimulatory and inhibitory factors.
Tarik Smani +7 more
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The Perilous PPI: Proton Pump Inhibitor as a Cause of Clinically Significant Hypomagnesaemia
Journal of the ASEAN Federation of Endocrine Societies, 2020 Proton pump inhibitors (PPIs) are the mainstay of therapy for all gastric acid related diseases and are commonly used in current clinical practice. Although widely regarded as safe, PPIs have been associated with a variety of adverse effects, including ...
Yong Ting Tai, Chin Voon Tong
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Contribution of calcium-conducting channels to the transport of zinc ions. [PDF]
, 2013 International audienceZinc (Zn) is a vital nutrient participating in a myriad of biological processes. The mechanisms controlling its transport through the plasma membrane are far from being completely understood.
Bouron, Alexandre, Oberwinkler, Johannes
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MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter. [PDF]
, 2018 Sodium (Na+) is a ubiquitous and important inorganic salt mediating many critical biological processes such as neuronal excitation, signaling, and facilitation of various transporters.
Gonen, Tamir, Liu, Shian
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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Voltage-gated ion channels [PDF]
, 2017 The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
, +11 more
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Structure of the full-length TRPV2 channel by cryo-EM. [PDF]
, 2016 Transient receptor potential (TRP) proteins form a superfamily Ca(2+)-permeable cation channels regulated by a range of chemical and physical stimuli. Structural analysis of a 'minimal' TRP vanilloid subtype 1 (TRPV1) elucidated a mechanism of channel ...
Cohen, Matthew R +6 more
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TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling [PDF]
, 2019 Calcium is an important second messenger required not only for the excitation-contraction coupling of the heart but also critical for the activation of cell signaling pathways involved in the adverse cardiac remodeling and consequently for the heart ...
Calderón Sánchez, Eva María +7 more
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Redox regulation of calcium ion channels: Chemical and physiological aspects [PDF]
, 2011 Reactive oxygen species (ROS) are increasingly recognized as second messengers in many cellular processes. While high concentrations of oxidants damage proteins, lipids and DNA, ultimately resulting in cell death, selective and reversible oxidation of ...
Bogeski, Ivan +5 more
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BMC Genomics, 2006 Background The purpose of this work was to study the gene expression of transient receptor potential (TRP) channels in the mouse. The application of a standardized and quantitative technique, TaqMan RT-PCR, should give information about the pattern and ...
Krüger Jana +3 more
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Association of hypermagnesemia and blood pressure in the critically ill [PDF]
, 2017 BACKGROUND: Although magnesium is important in the biology of blood pressure regulation, little clinical data exist on the association of hypermagnesemia and blood pressure.
Alper, Seth L. +7 more
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