Results 21 to 30 of about 1,001,638 (111)

The Perilous PPI: Proton Pump Inhibitor as a Cause of Clinically Significant Hypomagnesaemia

Journal of the ASEAN Federation of Endocrine Societies, 2020
Proton pump inhibitors (PPIs) are the mainstay of therapy for all gastric acid related diseases and are commonly used in current clinical practice. Although widely regarded as safe, PPIs have been associated with a variety of adverse effects, including ...
Yong Ting Tai, Chin Voon Tong
doaj   +1 more source

TRPM Channels Modulate Epileptic-like Convulsions via Systemic Ion Homeostasis [PDF]

, 2011
SummaryNeuronal networks operate over a wide range of activity levels, with both neuronal and nonneuronal cells contributing to the balance of excitation and inhibition.
Yishi Jin, Stawicki, Tamara M., Zhou, Keming, Jin, Yishi, Tamara M. Stawicki, Keming Zhou, Yochem, John, John Yochem, Chen, Lihsia, Lihsia Chen   +9 more
core   +1 more source

Lamellar ionenes with highly dissociative, anionic channels provide low barriers for cation transport [PDF]

, 2023
Solid polymer electrolytes have the potential to enable safer and more energy dense batteries; however, a deeper understanding of their ion conduction mechanisms, and how they can be optimized by rational molecular design, is needed to realize this goal.
Alberto, Concellón, Rafael, Gómez-Bombarelli, Christopher, Brown, Michael, Stolberg, Benjamin, Paren, Yang, Shao-Horn, Pablo, Leon, Gavin, Winter, Kiarash, Gordiz, Jeremiah, Johnson   +9 more
core   +2 more sources

TRPM channels are required for rhythmicity in the ultradian defecation rhythm of C. elegans. [PDF]

, 2008
BACKGROUND: Ultradian rhythms, rhythms with a period of less than 24 hours, are a widespread and fundamental aspect of life. The mechanisms underlying the control of such rhythms remain only partially understood. Defecation in C.
Kshamata Goyal, Rafael P Vázquez-Manrique, Howard A Baylis, Claire SM Kwan, Sung Ly   +4 more
core   +4 more sources

Vanilloid transient receptor potential cation channels: An overview [PDF]

, 2008
The mammalian branch of the Transient Receptor Potential ( TRP) superfamily of cation channels consists of 28 members. They can be subdivided in six main subfamilies: the TRPC ('Canonical'), TRPV ('Vanilloid'), TRPM ('Melastatin'), TRPP ('Polycystin ...
Vennekens, Rudi, Owsianik, Grzegorz, Nilius, Bernd   +2 more
core   +1 more source

Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes [PDF]

, 2009
We investigate activation mechanisms of native TRPC1/C5/C6 channels (termed TRPC1 channels) by stimulation of endothelin-1 (ET-1) receptor subtypes in freshly dispersed rabbit coronary artery myocytes using single channel recording and ...
Anthony P. Albert, Saleh, Sohag N., Albert, Anthony P., Sohag N. Saleh, William A. Large, Large, William A., Large, WA, Saleh, SN, Albert, AP   +8 more
core   +1 more source

Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains

BMC Genomics, 2006
Background The purpose of this work was to study the gene expression of transient receptor potential (TRP) channels in the mouse. The application of a standardized and quantitative technique, TaqMan RT-PCR, should give information about the pattern and ...
Krüger Jana, Bisping Frederike, Kunert-Keil Christiane, Brinkmeier Heinrich   +3 more
doaj   +1 more source

Estimating the sensitivity of mechanosensitive ion channels to membrane strain and tension [PDF]

, 2004
Bone adapts to its environment by a process in which osteoblasts and osteocytes sense applied mechanical strain. One possible pathway for the detection of strain involves mechanosensitive channels and we sought to determine their sensitivity to membrane ...
Charras, G.T., Sims, S.M., Sims, Stephen M., Charras, Guillaume T., Williams, B.A., Williams, Beatrice A., Horton, M.A., Horton, Mike A.   +7 more
core   +1 more source

Considerations about Study on Mechanisms of Thermal Efficacies of Moxibustion from Activities of Transient Receptor Potential Family

针刺研究, 2012
Of the mammalian transient receptor potential(TRP) superfamily members,transient receptor potential vanilloid 1(TRPV 1),TRPV 2,TRPV 3,TRPV 4,melastatin transient receptor potential(TRPM) 4,TRPM 5,and TRP ankyrin 1(TRPA 1),are mostly permeable to both ...
LU Sheng-feng1, 2, YIN Hai-yan2, TANG Yong2, ZHANG Cheng-shun2, YU Mei-ling3, LUO Ling2   +6 more
doaj   +2 more sources

TRPM channels come into focus

, 2018
The structures of TRPM channels help to explain how they can sense intracellular ...
Chanhyung Bae, Kenton J. Swartz, Andres Jara-Oseguera   +2 more
core   +1 more source