Results 151 to 160 of about 42,288 (305)
Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations [PDF]
, 2012 Yuanyuan Cui +5 more
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The Journal of Physiology, EarlyView.Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Transient receptor potential vanilloid-1 (TRPV1) channels act as suppressors of the growth of glioma
Brain Research BulletinThe aim of this study was to investigate the expression and function of the transient receptor potential vanilloid 1 (TRPV1) in glioma. We found that the expression of TRPV1 mRNA and protein were upregulated in glioma compared with normal brain by qPCR ...
Jingjing Cheng +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Using wild‐type and Trpv1−/− rats, we assessed the contribution of TRPV1 channels to the activation of afferent renal nerve activity (ARNA) during renal artery occlusion, graded reductions in renal blood flow and elevated renal pelvic pressure.
Jacob B. Sullivan +2 more
wiley +1 more source
Analysis of the Involvement of NMDA Receptors in Analgesia and Hypothermia Induced by the Activation of TRPV1 Ion Channels [PDF]
, 2023 Ivanova Ea +2 more
openalex +1 more source
Ischemic Neuroprotection by TRPV1 Receptor-Induced Hypothermia [PDF]
, 2012 Mirko Muzzi +7 more
openalex +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Clinical and Experimental GastroenterologyPrashant Singh,1 Gregory S Sayuk,2 David P Rosenbaum,3 Susan Edelstein,3 Kenji Kozuka,3 Lin Chang4 1Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; 2Department of Medicine, Washington University School of Medicine, St Louis ...
Singh P +5 more
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