Results 41 to 50 of about 25,827 (208)

TRPV1 in experimental autoimmune prostatitis [PDF]

The Prostate, 2019
AbstractBackgroundChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a disorder that is characterized by persistent pelvic pain in men of any age. Although several studies suggest that the transient receptor potential vanilloid 1 (TRPV1) channel is involved in various pathways of chronic pain, the TRPV1 channel has not been implicated in ...
Kenny Roman, Christel Hall, Anthony J. Schaeffer, Praveen Thumbikat   +3 more
openaire   +2 more sources

Central Sensitization-Related Changes in Brain Function Activity in a Rat Endometriosis-Associated Pain Model [Corrigendum]

Journal of Pain Research, 2020
Zheng P, Jia S, Guo D, et al. J Pain Res. 2020;13:95–107.During the final editing stages of manuscript preparation, the authors mistakenly repeated the Pain Cg1 and Tha images used in Figure 6 on page 103.
Zheng P, Jia S, Guo D, Chen S, Zhang W, Cheng A, Xie W, Sun G, Leng J, Lang J   +9 more
doaj  

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Anandamide and vanilloid TRPV1 receptors [PDF]

British Journal of Pharmacology, 2003
A large body of evidence now exists to substantiate that the endocannabinoid, anandamide, activates TRPV1 receptors. It is a low intrinsic efficacy TRPV1 agonist that behaves as a partial agonist in tissues with a low receptor reserve, while in tissues with high receptor reserve and in circumstances associated with certain disease states, it behaves as
openaire   +2 more sources

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Cannabidiol as a Novel Therapeutic for Immune Modulation

ImmunoTargets and Therapy, 2020
Nadia Peyravian,1,2 Sapna Deo,1,2 Sylvia Daunert,1– 3 Joaquin J Jimenez1,2,4 1Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA; 2Dr.
Peyravian N, Deo S, Daunert S, Jimenez JJ   +3 more
doaj  

Gastric hemorrhage due to high pungency food?

JPGN Reports, EarlyView.
Abstract We present a case of a 9‐year‐old patient who presented with hematemesis after consuming crisps with a high pungency (the so‐called ghost peppers). Blood loss resulted in a significant decrease in hemoglobin and for this reason a gastroduodenoscopy was performed.
Rachel J. van der Pol, Anemone van den Berg, Wendy L. van der Woerd   +2 more
wiley   +1 more source

Phosphoinositide regulation of TRPV1 revisited [PDF]

Pflügers Archiv - European Journal of Physiology, 2015
The heat- and capsaicin-sensitive transient receptor potential vanilloid 1 ion channel (TRPV1) is regulated by plasma membrane phosphoinositides. The effects of these lipids on this channel have been controversial. Recent articles re-ignited the debate and also offered resolution to place some of the data in a coherent picture.
openaire   +2 more sources

Multimodal Enhancement of Colonic Motility by Acupuncture at ST36 is Mediated by TRPV1+ Cutaneous Sensory Fibers

Frontiers in Bioscience-Landmark
Background: Acupuncture has been shown to promote gastrointestinal motility. This study explores whether cutaneous transient receptor potential vanilloid 1 (TRPV1)+ fibers at Zusanli (ST36) acupoint can mediate the multimodal effects ...
Nan Zhang, Huilin Chen, Xinyan Gao, Sha Li, Xia Li, Wang Li, Kun Liu, Shuya Wang, Bing Zhu   +8 more
doaj   +1 more source

Can trigeminal sensations impact saltiness perception? A mini‐review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan, Nicoletta Faraone, Matthew B McSweeney   +2 more
wiley   +1 more source