Results 31 to 40 of about 4,775 (199)
BMC Pulmonary Medicine, 2019 Background Defective phagocytosis in alveolar macrophages is associated with chronic obstructive pulmonary disease (COPD). Transient receptor potential cation channel subfamily V member 2 (TRPV2), a type of nonselective cation channel pertinent to ...
Hiroaki Masubuchi +11 more
doaj +1 more source
The TRPV2 cation channels: from urothelial cancer invasiveness to glioblastoma multiforme interactome signature [PDF]
, 2020 Changes in transient receptor potential (TRP) Ca2+ permeable channels are associated with development and progression of different types of cancer. Herein, we report data relative to the expression and function of TRP vanilloid 2 (TRPV2) channels in ...
Santoni, Matteo +6 more
core +2 more sources
Loss of TRPV2 Homeostatic Control of Cell Proliferation Drives Tumor Progression
Cells, 2014 Herein we evaluate the involvement of the TRPV2 channel, belonging to the Transient Receptor Potential Vanilloid channel family (TRPVs), in development and progression of different tumor types.
Sonia Liberati +8 more
doaj +1 more source
Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes
eLife, 2019 The Transient Receptor Potential Vanilloid 2 (TRPV2) channel is a member of the temperature-sensing thermoTRPV family. Recent advances in cryo-electronmicroscopy (cryo-EM) and X-ray crystallography have provided many important insights into the gating ...
Lejla Zubcevic +3 more
doaj +1 more source
Transient Receptor Potential Vanilloid 2 Regulates Myocardial Response to Exercise. [PDF]
PLoS ONE, 2015 The myocardial response to exercise is an adaptive mechanism that permits the heart to maintain cardiac output via improved cardiac function and development of hypertrophy. There are many overlapping mechanisms via which this occurs with calcium handling
Mindi Naticchioni +12 more
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Pharmacological inhibition of TRPV2 attenuates phagocytosis and lipopolysaccharide‐induced migration of primary macrophages [PDF]
, 2023 Background and Purpose: In macrophages, transient receptor potential vanilloid 2 (TRPV2) channel contributes to various cellular processes such as cytokine production, differentiation, phagocytosis and migration.
Raudszus, Rick +9 more
core +1 more source
Detection of endogenous TRPV2.
, 2013 A, Western blot analysis with anti-TRPV2 2D6 of F11 cells treated with control siRNA or TRPV2 siRNA (100 nM, 48 h). Quantification of the band corresponding to the molecular weight of TRPV2 was measured using LiCor Odyssey software.
Daniel Cawley (503968) +3 more
core +1 more source
Detection of recombinant TRPV2 and mapping of the TRPV2 binding region.
, 2013 A, Schematic of the domain arrangement for a TRPV2 monomer with the approximate epitope sites for indicated TRPV2 antibodies. ARD, ankryin repeat domain; TM, transmembrane domain.
Daniel Cawley (503968) +3 more
core +1 more source
TRPV2 and Diabetic Retinopathy:Oral presentation
, 2018 TRPV2 is a stretch-activated transient receptor potential channel present in neurons as well as cells of the vasculature. In the retina, we have reported that TRPV2 contributes to the myogenic constriction of retinal arterial vessels, a mechanism that ...
Esquiva Sobrino, Gema +7 more
core +2 more sources
Frontiers in Immunology, 2013 The Transient Receptor Potential Vanilloid type-2 (TRPV2), belonging to the TRP channel family, is a specialized ion channel expressed in human and other mammalian immune cells.
Giorgio eSantoni +7 more
doaj +1 more source