Results 51 to 60 of about 4,775 (199)

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Biophysical Characterization of TRPV2 Ion Channel [PDF]

Biophysical Journal, 2012
TRPV2 is a member of the superfamily of the Transient Receptor Potential (TRP) ion channels. These channels are assembled into homotetramers and allow cations across the membrane in response to physico-chemical stimuli such as heat, pressure, osmotic changes, etc. TRPV2 is an orphan receptor, since no specific endogenous ligand has been identified yet.
Perálvarez-Marín, Alex, Doñate-Macián, Pablo, Inada, Hitoshi, Mingarro, Ismael, Gaudet, Rachelle   +4 more
openaire   +1 more source

Immunostaining with TRPV2 antibodies.

, 2013
A, HeLa cells transiently expressing TRPV2-1D4 immunolabeled with indicated TRPV2 antibodies (green) and 1D4 antibody (red). Scale bar represents 10 µm.
Daniel Cawley (503968), Matthew R. Cohen (503966), Kevin W. Huynh (503967), Vera Y. Moiseenkova-Bell (503969)   +3 more
core   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

Charakterisierung und Funktion von TRPV2 Ionenkanälen in kortikalen Mikrogliazellen der Maus [PDF]

, 2021
Transkriptomanalysen unter Verwendung FACS-sortierter kortikaler Mikrogliazellen der Maus haben ergeben, dass Transkripte des Ionenkanals Trpv2 im Vergleich zu anderen Ionenkanälen der TRP-Familie stark exprimiert werden. In meiner Masterarbeit hatte ich
Malihpour, Mahsa
core   +1 more source

TRPM4 and TRPV2 are two novel prognostic biomarkers and promising targeted therapy in UVM

Frontiers in Molecular Biosciences, 2022
Uveal melanoma (UVM) is the most common primary intraocular malignancy tumor in adults. Almost 50% of UVM patients develop metastatic disease, and is usually fatal within 1 year. However, the mechanism of etiology remains unclear. The lack of prognostic,
Jiong Wang, Sen Qiao, Shenzhi Liang, Cheng Qian, Yi Dong, Minghang Pei, Hongmei Wang, Guangming Wan   +7 more
doaj   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

The Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

TRPV2 protein expression analysis.

, 2015
(A) Western blot and (B) IHC staining in WT and TRPV2-KO mouse hearts.
Sheryl E. Koch (793860), Min Jiang (56794), Tatiana Radzyukevich (793857), Ryan Apel (793858), Nathan Robbins (491110), Xu Gao (51798), Jack Rubinstein (491112), Mindi Naticchioni (793853), Rajiv Karani (793854), Logan Fulford (634792), Margaret A. Smith (793855), Evan Onusko (793856), Judith Heiny (793859)   +12 more
core   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

TRPV2: A Key Player in Myelination Disorders of the Central Nervous System [PDF]

, 2022
Transient potential receptor vanilloid 2 (TRPV2) is widely expressed through the nervous system and specifically found in neuronal subpopulations and some glial cells.
Enrich Bengoa, Jennifer, Solà i Subirana, Carme, Paula Sanchez-Molina, Solà, Carme, Sanchez-Molina, Paula, Saura Martí, Josep, Castellano, Bernardo, Alex Perálvarez-Marín, Perálvarez-Marín, Alex, Almolda Ardid, Beatriz, Tony Valente, Gemma Manich, Berta González, Manich Raventós, Gemma, Almolda, Beatriz, Universitat Autònoma de Barcelona. Institut de Neurociències, Sanchez Molina, Paula, Manich, Gemma, Enrich-Bengoa, Jennifer, Beatriz Almolda, González, Berta, Jennifer Enrich-Bengoa, Carme Solà, Josep Saura, Castellano López, Bernardo, Perálvarez Marín, Alex, Valente, Tony, Bernardo Castellano, Saura, Josep   +28 more
core   +1 more source