Results 111 to 120 of about 5,561 (208)

Camphor, Applied Epidermally to the Back, Causes Snout- and Chest-Grooming in Rats: A Response Mediated by Cutaneous TRP Channels

open access: yesPharmaceuticals, 2019
Thermoregulatory grooming, a behavioral defense against heat, is known to be driven by skin-temperature signals. Because at least some thermal cutaneous signals that drive heat defenses are likely to be generated by transient receptor potential (TRP ...
Débora T. Ishikawa   +5 more
doaj   +1 more source

TRPV3 expression and purification for structure determination by Cryo-EM

open access: yes, 2021
The transient receptor potential vanilloid-superfamily member 3 (TRPV3) channel is implicated in a variety of physiological processes, including temperature sensing, nociception and itch, maintenance of the skin barrier, wound healing, hair growth, and embryonic development.
Arthur, Neuberger   +2 more
openaire   +3 more sources

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects [PDF]

open access: yes, 2015
Funded by: •GW Pharmaceuticals Acknowledgements: The authors wish to thank Mrs Lesley Stevenson for technical support and Dr John Raymond, Dr Keith Parker and Dr Ethan Russo for providing human 5-HT1A CHO cells.
Cascio, Maria Grazia   +4 more
core   +1 more source

Transient Receptor Potential Cation Channel Subfamily Vanilloid 4 and 3 in the Inner Ear Protect Hearing in Mice

open access: yesFrontiers in Molecular Neuroscience, 2019
The transient receptor potential cation channel, vanilloid type (TRPV) 3, is a member of the TRPV subfamily that is expressed predominantly in the skin, hair follicles, and gastrointestinal tract. It is also distributed in the organ of Corti of the inner
Shengnan Wang   +33 more
doaj   +1 more source

Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain

open access: yesBMC Women's Health, 2005
Background Breast pain and tenderness affects 70% of women at some time. These symptoms have been attributed to stretching of the nerves with increase in breast size, but tissue mechanisms are poorly understood.
Facer Paul   +7 more
doaj   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Voltage-gated ion channels [PDF]

open access: yes, 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,   +11 more
core   +5 more sources

Ocular transient receptor potential channel function in health and disease [PDF]

open access: yes, 2015
Transient receptor potential (TRP) channels sense and transduce environmental stimuli into Ca2+ transients that in turn induce responses essential for cell function and adaptation.
Mergler, Stefan   +3 more
core   +1 more source

Ca2+ dynamics in oocytes from naturally-aged mice [PDF]

open access: yes, 2016
The ability of human metaphase-II arrested eggs to activate following fertilisation declines with advancing maternal age. Egg activation is triggered by repetitive increases in intracellular Ca2+ concentration ([Ca2+]i) in the ooplasm as a result of ...
FitzHarris, Greg   +7 more
core   +3 more sources

Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic

open access: yesCell Reports, 2015
Woolly mammoths and living elephants are characterized by major phenotypic differences that have allowed them to live in very different environments. To identify the genetic changes that underlie the suite of woolly mammoth adaptations to extreme cold ...
Vincent J. Lynch   +7 more
doaj   +1 more source

Az endocannabinoid rendszer szerepe és szabályozása a humán faggyúmirigyben = Role and regulation of the endocannabinoid system in the human sebaceous gland [PDF]

open access: yes, 2011
Nagymértékben fókuszált, alapkutatási projektünkben – melyet egy szakértő, multidiszciplináris kutatói team nemzetközi kollaboráció keretében valósított meg – szisztematikusan és mechanisztikusan térképeztük fel az endokannabinoid rendszer (ECS) szerepét
Borbíró, István   +7 more
core  

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