Results 21 to 30 of about 3,271 (166)
MicroRNA-369 attenuates hypoxia-induced cardiomyocyte apoptosis and inflammation via targeting TRPV3 [PDF]
Brazilian Journal of Medical and Biological Research, 2021 Hypoxia-induced apoptosis and inflammation play an important role in cardiovascular diseases including myocardial infarction (MI). miR-369 has been suggested to be a key regulator of cardiac fibrosis.
Jinghao Wang, Xu Chen, Wei Huang
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International Journal of Molecular Sciences, 2022 Itching is a sensory phenomenon characterized by an unpleasant sensation that makes you want to scratch the skin, and chronic itching diminishes the quality of life. In recent studies, multiple transient receptor potential (TRP) channels present in keratinocytes or nerve endings have been shown to engage in the propagation of itch signals in chronic ...
Ji Young Um +7 more
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Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin. [PDF]
J PhysiolAbstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Alemayhu AM, Paulsen CE.
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TRPV3 as a Therapeutic Target for Itch [PDF]
Journal of Investigative Dermatology, 2012 Abbreviations: AD, atopic dermatitis; AEW, acetone ether water; PGP9.5, protein gene product 9.5; TRPV3, transient receptor potential vanilloid subfamily ...
Yamamoto-Kasai, Erika +7 more
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Preventing a Perm with TRPV3 [PDF]
Cell, 2010 Epidermal growth factor receptor (EGFR) signaling is instrumental for terminal differentiation of keratinocytes, hair morphogenesis, and maintenance of the skin barrier. Cheng et al. (2010) now demonstrate that the calcium-permeable channel TRPV3 is required for these EGFR-dependent functions.
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Journal of Pharmacy & Pharmaceutical Sciences, 2009 Transient receptor potential vanilloid-3 (TRPV3) is a thermo-sensitive ion channel expressed in skin keratinocytes and in a variety of neural cells. It is activated by warmth as well as monoterpenoids including camphor, menthol, dihydrocarveol and 1,8 ...
Muhammad Azhar Sherkheli +6 more
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Supercooling Agent Icilin Blocks a Warmth-Sensing Ion Channel TRPV3
The Scientific World Journal, 2012 Transient receptor potential vanilloid subtype 3 (TRPV3) is a thermosensitive ion channel expressed in a variety of neural cells and in keratinocytes. It is activated by warmth (33–39°C), and its responsiveness is dramatically increased at nociceptive ...
Muhammad Azhar Sherkheli +2 more
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Localization of TRPV3/4 and PIEZO1/2 sensory receptors in murine and human larynges
Laryngoscope Investigative Otolaryngology, 2022 Objective The primary aim of this study was to identify expression of TRPV3 and TRPV4 chemoreceptors across perinatal and adult stages using a murine model with direct comparisons to human laryngeal mucosa.
Alexander G. Foote +3 more
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Frontiers in Immunology, 2022 BackgroundThe transient receptor potential vanilloid (TRPV) channels family, TRPV1-6, has been identified to profoundly affect a wide spectrum of pathological processes in various cancers. However, the biological function and prognostic value of TRPVs in
Yuxiong Jiang +8 more
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TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation
Molecular Pain, 2011 Background The discovery of heat-sensitive Transient Receptor Potential Vanilloid (TRPV) ion channels provided a potential molecular explanation for the perception of innocuous and noxious heat stimuli.
Wang Juan +4 more
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